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Timo Leppänen, Mikko Särkkä, Antti Kulkas, Anu Muraja-Murro, Salla Kupari, Meri Anttonen, Pekka Tiihonen, Esa Mervaala & Juha Töyräs. (2016) RemLogic plug-in enables clinical application of apnea-hypopnea index adjusted for severity of individual obstruction events. Journal of Medical Engineering & Technology 40:3, pages 119-126.
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Kareem Abu, Massoud L. Khraiche & Jason Amatoury. (2024) Obstructive sleep apnea diagnosis and beyond using portable monitors. Sleep Medicine 113, pages 260-274.
Crossref
Crossref
Akshayraj Langaliya, Mohammad Khursheed Alam, Usha Hegde, Mangesh Shenoy Panakaje, Gabriele Cervino & Giuseppe Minervini. (2023)
Occurrence of Temporomandibular Disorders among patients undergoing treatment for Obstructive Sleep Apnoea Syndrome (OSAS) using Mandibular Advancement Device (MAD): A Systematic Review conducted according to
PRISMA
guidelines and the Cochrane handbook for systematic reviews of interventions
. Journal of Oral Rehabilitation 50:12, pages 1554-1563.
Crossref
Crossref
Henri Korkalainen, Samu Kainulainen, Anna Sigridur Islind, María Óskarsdóttir, Christian Strassberger, Sami Nikkonen, Juha Töyräs, Antti Kulkas, Ludger Grote, Jan Hedner, Reijo Sund, Harald Hrubos-Strom, Jose M. Saavedra, Kristín Anna Ólafsdóttir, Jón S. Ágústsson, Philip I. Terrill, Walter T. McNicholas, Erna Sif Arnardóttir & Timo Leppänen. (2023) Review and perspective on sleep-disordered breathing research and translation to clinics. Sleep Medicine Reviews, pages 101874.
Crossref
Crossref
Siying He, Peter A. Cistulli & Philip de Chazal. (2023) A Review of Novel Oximetry Parameters for the Prediction of Cardiovascular Disease in Obstructive Sleep Apnoea. Diagnostics 13:21, pages 3323.
Crossref
Crossref
Susan Redline, Ali Azarbarzin & Yüksel Peker. (2023) Obstructive sleep apnoea heterogeneity and cardiovascular disease. Nature Reviews Cardiology 20:8, pages 560-573.
Crossref
Crossref
Purbanka Pahari, Henri Korkalainen, Tuomas Karhu, Erna Sif Arnardottir, Juha Töyräs, Timo Leppänen & Sami Nikkonen. (2023) Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea. Journal of Sleep Research.
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Crossref
András Bikov, Stefan Frent, Oana Deleanu, Martina Meszaros, Mariela Romina Birza, Alina Mirela Popa, Andrei Raul Manzur, Loredana Gligor & Stefan Mihaicuta. (2023) Time Spent with Saturation below 80% versus 90% in Patients with Obstructive Sleep Apnoea. Journal of Clinical Medicine 12:13, pages 4205.
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Purbanka Pahari, Henri Korkalainen, Tuomas Karhu, Marika Rissanen, Erna Sif Arnardottir, Harald Hrubos‐Strøm, Brett Duce, Juha Töyräs, Timo Leppänen & Sami Nikkonen. (2022) Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance. Journal of Sleep Research 32:3.
Crossref
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Mikke Varis, Tuomas Karhu, Timo Leppänen & Sami Nikkonen. (2023) Utilizing Envelope Analysis of a Nasal Pressure Signal for Sleep Apnea Severity Estimation. Diagnostics 13:10, pages 1776.
Crossref
Crossref
Arie Oksenberg & Timo Leppänen. (2023) Duration of respiratory events in obstructive sleep apnea: In search of paradoxical results. Sleep Medicine Reviews 68, pages 101728.
Crossref
Crossref
Hans Christian Hoel, Knut Kvinnesland & Sören Berg. (2023) Outcome of nasal measurements in patients with OSA – Mounting evidence of a nasal endotype. Sleep Medicine 103, pages 131-137.
Crossref
Crossref
Miguel A. Martinez-Garcia, Manuel Sánchez-de-la-Torre, David P. White & Ali Azarbarzin. (2023) Hypoxic Burden in Obstructive Sleep Apnea: Present and Future. Archivos de Bronconeumología 59:1, pages 36-43.
Crossref
Crossref
Daniel Álvarez, Andrea Crespo, Leila Kheirandish-Gozal, David Gozal & Félix del Campo. 2023. Sleep Medicine. Sleep Medicine
69
95
.
Jonathan C. Jun. (2022) Dying with OSA, or from It: A Cautionary Note about Novel Hypoxia Metrics. American Journal of Respiratory and Critical Care Medicine 206:12, pages 1563-1564.
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Crossref
Ki-Hwan Ji. (2022) Phenotypic Approach to Obstructive Sleep Apnea. Journal of Sleep Medicine 19:3, pages 97-106.
Crossref
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Tuomas Karhu, Timo Leppänen, Henri Korkalainen, Sami Myllymaa, Brett Duce, Juha Töyräs & Sami Nikkonen. (2022) Desaturation event scoring criteria affect the perceived severity of nocturnal hypoxic load. Sleep Medicine 100, pages 479-486.
Crossref
Crossref
Tuomas Karhu, Timo Leppänen, Juha Töyräs, Arie Oksenberg, Sami Myllymaa & Sami Nikkonen. (2022) ABOSA – Freely available automatic blood oxygen saturation signal analysis software: Structure and validation. Computer Methods and Programs in Biomedicine 226, pages 107120.
Crossref
Crossref
Fjola D. Sigurdardottir, Caroline Tonje Øverby, Sami Nikkonen, Tuomas Karhu, Toril Dammen, Inger Hilde Nordhus, Thea Thorshov, Gunnar Einvik, Samu Kainulainen, Timo Leppänen, Erna Sif Arnardottir, Juha Töyräs, Torbjørn Omland & Harald Hrubos‐Strøm. (2022) Novel oxygen desaturation parameters are associated with cardiac troponin I: Data from the Akershus Sleep Apnea Project. Journal of Sleep Research 31:5.
Crossref
Crossref
Miguel A. Martinez-Garcia, Manuel Sánchez-de-la-Torre, David P. White & Ali Azarbarzin. (2022) Hypoxic Burden in Obstructive Sleep Apnea: Present and Future. Archivos de Bronconeumología.
Crossref
Crossref
Erna S. Arnardottir, Anna Sigridur Islind, María Óskarsdóttir, Kristín A. Ólafsdóttir, Elias August, Lára Jónasdóttir, Harald Hrubos‐Strøm, Jose M. Saavedra, Ludger Grote, Jan Hedner, Sveinbjörn Höskuldsson, Jón Skírnir Ágústsson, Kamilla Rún Jóhannsdóttir, Walter T. McNicholas, Dirk Pevernagie, Reijo Sund, Juha Töyräs & Timo Leppänen. (2022) The Sleep Revolution project: the concept and objectives. Journal of Sleep Research 31:4.
Crossref
Crossref
Tuomas Karhu, Sami Myllymaa, Sami Nikkonen, Diego R. Mazzotti, Antti Kulkas, Juha Töyräs & Timo Leppänen. (2021) Diabetes and cardiovascular diseases are associated with the worsening of intermittent hypoxaemia. Journal of Sleep Research 31:1.
Crossref
Crossref
Daniel Álvarez, Gonzalo C. Gutiérrez-Tobal, Fernando Vaquerizo-Villar, Fernando Moreno, Félix del Campo & Roberto Hornero. 2022. Advances in the Diagnosis and Treatment of Sleep Apnea. Advances in the Diagnosis and Treatment of Sleep Apnea
219
239
.
Gonzalo C. Gutiérrez-Tobal, Javier Gomez-Pilar, Leila Kheirandish-Gozal, Adrián Martín-Montero, Jesús Poza, Daniel Álvarez, Félix del Campo, David Gozal & Roberto Hornero. (2021) Pediatric Sleep Apnea: The Overnight Electroencephalogram as a Phenotypic Biomarker. Frontiers in Neuroscience 15.
Crossref
Crossref
Philip de Chazal, Nadi Sadr, Hasthi Dissanayake, Kristina Cook, Kate Sutherland, Yu Sun Bin & Peter A. Cistulli. (2021) Predicting Cardiovascular Outcomes Using the Respiratory Event Desaturation Transient Area Derived from Overnight Sleep Studies. Predicting Cardiovascular Outcomes Using the Respiratory Event Desaturation Transient Area Derived from Overnight Sleep Studies.
Timo Leppänen, Sami Myllymaa, Antti Kulkas & Juha Töyräs. (2021) Beyond the apnea–hypopnea index: alternative diagnostic parameters and machine learning solutions for estimation of sleep apnea severity. SLEEP 44:9.
Crossref
Crossref
Tuomas Karhu, Sami Myllymaa, Sami Nikkonen, Diego R. Mazzotti, Juha Töyräs & Timo Leppänen. (2021) Longer and Deeper Desaturations Are Associated With the Worsening of Mild Sleep Apnea: The Sleep Heart Health Study. Frontiers in Neuroscience 15.
Crossref
Crossref
T. Leppänen, A. Kulkas, J. Töyräs, S. Myllymaa, N. Gadoth & A. Oksenberg. (2020) Polysomnographic characteristics of severe obstructive sleep apnea vary significantly between hypertensive and normotensive patients of both genders. Sleep and Breathing 25:1, pages 105-116.
Crossref
Crossref
Akseli Leino, Susanna Westeren-Punnonen, Juha Töyräs, Sami Myllymaa, Timo Leppänen, Salla Ylä-Herttuala, Anu Muraja-Murro, Anne-Mari Kantanen, Jaana Autere, Pekka Jäkälä, Esa Mervaala & Katja Myllymaa. (2020) Acute stroke and TIA patients have specific polygraphic features of obstructive sleep apnea. Sleep and Breathing 24:4, pages 1495-1505.
Crossref
Crossref
Philip I. Terrill. (2020) A review of approaches for analysing obstructive sleep apnoea‐related patterns in pulse oximetry data. Respirology 25:5, pages 475-485.
Crossref
Crossref
Samu Kainulainen, Brett Duce, Henri Korkalainen, Arie Oksenberg, Akseli Leino, Erna S. Arnardottir, Antti Kulkas, Sami Myllymaa, Juha Töyräs & Timo Leppänen. (2020) Severe desaturations increase psychomotor vigilance task-based median reaction time and number of lapses in obstructive sleep apnoea patients. European Respiratory Journal 55:4, pages 1901849.
Crossref
Crossref
Daniel Álvarez, Ana Cerezo-Hernández, Andrea Crespo, Gonzalo C. Gutiérrez-Tobal, Fernando Vaquerizo-Villar, Verónica Barroso-García, Fernando Moreno, C. Ainhoa Arroyo, Tomás Ruiz, Roberto Hornero & Félix del Campo. (2020) A machine learning-based test for adult sleep apnoea screening at home using oximetry and airflow. Scientific Reports 10:1.
Crossref
Crossref
Sami Nikkonen, Juha Töyräs, Esa Mervaala, Sami Myllymaa, Philip Terrill & Timo Leppänen. (2019) Intra-night variation in apnea-hypopnea index affects diagnostics and prognostics of obstructive sleep apnea. Sleep and Breathing 24:1, pages 379-386.
Crossref
Crossref
Henri Korkalainen, Juha Töyräs, Sami Nikkonen & Timo Leppänen. (2019) Mortality‐risk‐based apnea–hypopnea index thresholds for diagnostics of obstructive sleep apnea. Journal of Sleep Research 28:6.
Crossref
Crossref
Anna Alessandri-Bonetti, Francesco Bortolotti, Isabel Moreno-Hay, Ambra Michelotti, Massimo Cordaro, Giulio Alessandri-Bonetti & Jeffrey P. Okeson. (2019) Effects of mandibular advancement device for obstructive sleep apnea on temporomandibular disorders: A systematic review and meta-analysis. Sleep Medicine Reviews 48, pages 101211.
Crossref
Crossref
Ali Azarbarzin, Scott A Sands, David P White, Susan Redline & Andrew Wellman. (2019) The hypoxic burden: a novel sleep apnoea severity metric and a predictor of cardiovascular mortality—Reply to ‘The hypoxic burden: also known as the desaturation severity parameter’. European Heart Journal 40:35, pages 2994-2995.
Crossref
Crossref
Timo Leppänen, Antti Kulkas & Juha Töyräs. (2019) The hypoxic burden: also known as the desaturation severity parameter. European Heart Journal 40:35, pages 2991-2993.
Crossref
Crossref
Antti Kulkas, Timo Leppänen, Sami Nikkonen, Arie Oksenberg, Brett Duce, Esa Mervaala & Juha Töyräs. (2018) Required CPAP usage time to normalize AHI in obstructive sleep apnea patients: a simulation study. Physiological Measurement 39:11, pages 115009.
Crossref
Crossref
Marcello Bosi, Andrea De Vito, Bhik Kotecha, Luca Viglietta, Alberto Braghiroli, Joerg Steier, Martino Pengo, Giovanni Sorrenti, Riccardo Gobbi, Claudio Vicini & Venerino Poletti. (2018) Phenotyping the pathophysiology of obstructive sleep apnea using polygraphy/polysomnography: a review of the literature. Sleep and Breathing 22:3, pages 579-592.
Crossref
Crossref
Olli-Pekka Ryynänen, Timo LeppänenPekka KekolahtiEsa MervaalaJuha Töyräs. (2018) Bayesian Network Model to Evaluate the Effectiveness of Continuous Positive Airway Pressure Treatment of Sleep Apnea. Healthcare Informatics Research 24:4, pages 346.
Crossref
Crossref
Timo Leppänen, Juha Töyräs, Esa Mervaala, Thomas Penzel & Antti Kulkas. (2017) Severity of individual obstruction events increases with age in patients with obstructive sleep apnea. Sleep Medicine.
Crossref
Crossref
Timo Leppänen, Antti Kulkas, Brett Duce, Esa Mervaala & Juha Töyräs. (2016) Severity of individual obstruction events is gender dependent in sleep apnea. Sleep and Breathing 21:2, pages 397-404.
Crossref
Crossref
Hao Wu, Xiaojun Zhan, Mengneng Zhao & Yongxiang Wei. (2016) Mean apnea–hypopnea duration (but not apnea–hypopnea index) is associated with worse hypertension in patients with obstructive sleep apnea. Medicine 95:48, pages e5493.
Crossref
Crossref
Timo Leppänen, Juha Töyräs, Anu Muraja-Murro, Salla Kupari, Pekka Tiihonen, Esa Mervaala & Antti Kulkas. (2016) Length of Individual Apnea Events Is Increased by Supine Position and Modulated by Severity of Obstructive Sleep Apnea. Sleep Disorders 2016, pages 1-13.
Crossref
Crossref
A. Kulkas, T. Leppänen, J. Sahlman, P. Tiihonen, E. Mervaala, J. Kokkarinen, J. Randell, J. Seppä, J. Töyräs & H. Tuomilehto. (2015) Amount of weight loss or gain influences the severity of respiratory events in sleep apnea. Medical & Biological Engineering & Computing 53:10, pages 975-988.
Crossref
Crossref
Antti Kulkas, Anu Muraja-Murro, Pekka Tiihonen, Esa Mervaala & Juha Töyräs. (2014) Morbidity and mortality risk ratios are elevated in severe supine dominant OSA: a long-term follow-up study. Sleep and Breathing 19:2, pages 653-660.
Crossref
Crossref
A Kulkas, T Leppänen, J Sahlman, P Tiihonen, E Mervaala, J Kokkarinen, J Randell, J Seppä, J Töyräs & H Tuomilehto. (2014) Weight loss alters severity of individual nocturnal respiratory events depending on sleeping position. Physiological Measurement 35:10, pages 2037-2052.
Crossref
Crossref
A. Muraja-Murro, A. Kulkas, M. Hiltunen, S. Kupari, T. Hukkanen, P. Tiihonen, E. Mervaala & J. Töyräs. (2014) Adjustment of apnea-hypopnea index with severity of obstruction events enhances detection of sleep apnea patients with the highest risk of severe health consequences. Sleep and Breathing 18:3, pages 641-647.
Crossref
Crossref
Anu Muraja-Murro, Antti Kulkas, Mikko Hiltunen, Salla Kupari, Taina Hukkanen, Pekka Tiihonen, Esa Mervaala & Juha Töyräs. (2013) The severity of individual obstruction events is related to increased mortality rate in severe obstructive sleep apnea. Journal of Sleep Research 22:6, pages 663-669.
Crossref
Crossref
A Kulkas, T Leppänen, J Sahlman, P Tiihonen, E Mervaala, J Kokkarinen, J Randell, J Seppä, H Tuomilehto & J Töyräs. (2013) Novel parameters reflect changes in morphology of respiratory events during weight loss. Physiological Measurement 34:9, pages 1013-1026.
Crossref
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