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Review Article

Types of stereoselectivity in drug metabolism: a heuristic approach

Pages 239-251 | Received 13 Sep 2014, Accepted 03 Nov 2014, Published online: 20 Nov 2014

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Jing Gu, Zheng Sui, Chunshu Fang & Qunyou Tan. (2017) Stereochemical considerations in pharmacokinetic processes of representative antineoplastic agents. Drug Metabolism Reviews 49:4, pages 438-450.
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Maria Miguel Coelho, Carla Fernandes, Fernando Remião & Maria Elizabeth Tiritan. (2021) Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods. Molecules 26:11, pages 3113.
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Yun Xie, Leon Yu Zheng Li, Weiyu Hao, Jing Chang, Peng Xu, Baoyuan Guo, Jianzhong Li & Huili Wang. (2019) Comparative toxicokinetics and tissue distribution of prothioconazole and prothioconazole-desthio in Chinese lizards (Eremias argus) and transcriptional responses of metabolic-related genes. Environmental Pollution 247, pages 524-533.
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Xiao-Long Hu, Cui Guo, Ji-Qin Hou, Jia-Hao Feng, Xiao-Qi Zhang, Fei Xiong, Wen-Cai Ye & Hao Wang. (2018) Stereoisomers of Schisandrin B Are Potent ATP Competitive GSK-3β Inhibitors with Neuroprotective Effects against Alzheimer’s Disease: Stereochemistry and Biological Activity. ACS Chemical Neuroscience 10:2, pages 996-1007.
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Vera Yu. Kuksenok, Victoria V. Shtrykova, Victor D. Filimonov, Alexandr G. Druganov, Alexandr A. Bondarev & Ksenia S. Stankevich. (2018) The determination of enantiomer composition of 1-((3-chlorophenyl)-(phenyl)methyl) amine and 1-((3-chlorophenyl)(phenyl)-methyl) urea (Galodif) by NMR spectroscopy, chiral HPLC, and polarimetry. Chirality 30:10, pages 1135-1143.
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Wei Peng & Fei Ding. (2017) Enantioselective recognition of an isomeric ligand by a biomolecule: mechanistic insights into static and dynamic enantiomeric behavior and structural flexibility. Molecular BioSystems 13:11, pages 2226-2234.
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Bernard Testa, Giulio Vistoli & Alessandro Pedretti. (2016) Mechanisms and pharmaceutical consequences of processes of stereoisomerisation ? A didactic excursion. European Journal of Pharmaceutical Sciences 88, pages 101-123.
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Zhuowei Shen, Chuang Lv & Su Zeng. (2016) Significance and challenges of stereoselectivity assessing methods in drug metabolism. Journal of Pharmaceutical Analysis 6:1, pages 1-10.
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