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Review Article

The modulation of carbonyl reductase 1 by polyphenols

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Pages 520-533 | Received 02 Jul 2015, Accepted 31 Aug 2015, Published online: 29 Sep 2015

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Sophia M. Shi & Li Di. (2017) The role of carbonyl reductase 1 in drug discovery and development. Expert Opinion on Drug Metabolism & Toxicology 13:8, pages 859-870.
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Minako Yokoyama, Toshitsugu Fujita, Yuka Kadonosawa, Yota Tatara, Daisuke Motooka, Masahito Ikawa, Hodaka Fujii & Yoshihito Yokoayama. (2022) Development of transgenic mice overexpressing mouse carbonyl reductase 1. Molecular Biology Reports 50:1, pages 531-540.
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Pio Conti, Alessandro Caraffa, Carla E. Gallenga, Rhiannon Ross, Spyros K. Kritas, Ilyas Frydas, Alì Younes, Paolo Di Emidio, Gianpaolo Ronconi & Franco Pandolfi. (2021) Powerful anti‐inflammatory action of luteolin: Potential increase with IL‐38. BioFactors 47:2, pages 165-169.
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Kui Liu, Miao Luo & Shuang Wei. (2019) The Bioprotective Effects of Polyphenols on Metabolic Syndrome against Oxidative Stress: Evidences and Perspectives. Oxidative Medicine and Cellular Longevity 2019, pages 1-16.
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Michaela Šadibolová, Tomáš Zárybnický, Tomáš Smutný, Petr Pávek, Zdeněk Šubrt, Petra Matoušková, Lenka Skálová & Iva Boušová. (2019) Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver. International Journal of Molecular Sciences 20:18, pages 4562.
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Jan Moritz Seliger, Hans-Jörg Martin, Edmund Maser & Jan Hintzpeter. (2019) Potent inhibition of human carbonyl reductase 1 (CBR1) by the prenylated chalconoid xanthohumol and its related prenylflavonoids isoxanthohumol and 8-prenylnaringenin. Chemico-Biological Interactions 305, pages 156-162.
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Linh Thuy Nguyen, Zuzana Myslivečková, Barbora Szotáková, Alena Špičáková, Kateřina Lněničková, Martin Ambrož, Vladimír Kubíček, Kristýna Krasulová, Pavel Anzenbacher & Lenka Skálová. (2017) The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro. Chemico-Biological Interactions 278, pages 123-128.
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Roberta Moschini, Rossella Rotondo, Giovanni Renzone, Francesco Balestri, Mario Cappiello, Andrea Scaloni, Umberto Mura & Antonella Del-Corso. (2017) Kinetic features of carbonyl reductase 1 acting on glutathionylated aldehydes. Chemico-Biological Interactions 276, pages 127-132.
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Ruth A. Morgan, Katharina R. Beck, Mark Nixon, Natalie Z. M. Homer, Andrew A. Crawford, Diana Melchers, René Houtman, Onno C. Meijer, Andreas Stomby, Anna J. Anderson, Rita Upreti, Roland H. Stimson, Tommy Olsson, Tom Michoel, Ariella Cohain, Arno Ruusalepp, Eric E. Schadt, Johan L. M. Björkegren, Ruth Andrew, Christopher J. Kenyon, Patrick W. F. Hadoke, Alex Odermatt, John A. Keen & Brian R. Walker. (2017) Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity. Scientific Reports 7:1.
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Akira Hara, Satoshi Endo, Toshiyuki Matsunaga, Ossama El-Kabbani, Takeshi Miura, Toru Nishinaka & Tomoyuki Terada. (2017) Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. Biochemical Pharmacology 138, pages 185-192.
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Alena Špičáková, Barbora Szotáková, Diana Dimunová, Zuzana Myslivečková, Vladimír Kubíček, Martin Ambrož, Kateřina Lněničková, Kristýna Krasulová, Pavel Anzenbacher & Lenka Skálová. (2017) Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions. Molecules 22:4, pages 509.
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