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Research Article

Metabolism of Hydrazine Derivatives of Pharmacologic Interest

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Pages 71-100 | Published online: 22 Sep 2008

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Bernard Testa. (1982) Nonenzymatic Contributions to Xenobiotic Metabolism. Drug Metabolism Reviews 13:1, pages 25-50.
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John A. Timbrell. (1979) The Role of Metabolism in the Hepatotoxicity of Isoniazid and Iproniazid. Drug Metabolism Reviews 10:1, pages 125-147.
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Peter Jenner & Bernard Testa. (1978) Novel Pathways in Drug Metabolism. Xenobiotica 8:1, pages 1-25.
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Z. H. Israili & P. G. Dayton. (1977) Metabolism of Hydralazine. Drug Metabolism Reviews 6:2, pages 283-305.
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Virág Bogdándi, Gábor Lente & István Fábián. (2015) Kinetics of the oxidation of isoniazid with the hypochlorite ion. RSC Advances 5:83, pages 67500-67508.
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Jinheung Kim, Sangmi Lee, Joo Hyeon Nam, Young Jun Cho, Joohoon Kim, Jae Yeol Lee, Ho-Jung Kang, Sehoon Kim, Hoon Tae Kim, Heung Mok Park & Jungahn Kim. (2011) Synthesis of PEO-based block copolymers bearing cyclic hydrazide or carboxylic acid moieties and their applications as stabilizers for Fe3O4 nanoparticles. Macromolecular Research 19:7, pages 716-721.
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Marcia Gamberini & Luciana C.C. Leite. (1997) Proliferation of Mouse Fibroblasts Induced by 1,2-Dimethylhydrazine Auto-Oxidation: Role of Iron and Free Radicals. Biochemical and Biophysical Research Communications 234:1, pages 44-47.
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Douglas C. Goodwin, Steven D. Aust & Thomas A. Grover. (1996) Free Radicals Produced during the Oxidation of Hydrazines by Hypochlorous Acid. Chemical Research in Toxicology 9:8, pages 1333-1339.
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G.V. Rumyantseva, C.H. Kennedy & R.P. Mason. (1991) Trace transition metal-catalyzed reactions in the microsomal metabolism of alkyl hydrazines to carbon-centered free radicals.. Journal of Biological Chemistry 266:32, pages 21422-21427.
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Birandra Kumar Sinha & Ann G. Motten. (1982) Oxidative metabolism of hydralazine. Evidence for nitrogen centered radicals formation. Biochemical and Biophysical Research Communications 105:3, pages 1044-1051.
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M. Ebadi, C.F. Gessert & A. Al-Sayegh. (1982) DRUG-PYRIDOXAL PHOSPHATE INTERACTIONS. Drug Metabolism and Drug Interactions 4:4.
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T. M. Ludden, J. L. McnayJR.JR., A. M. M. Shepherd & M. S. Lin. (2005) Variability of plasma hydralazine concentrations in male hypertensive patients. Arthritis & Rheumatism 24:8, pages 987-992.
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B. Toth. (1980) Actual new cancer-causing hydrazines, hydrazides, and hydrazonesAktuelle neue krebsverursachende Hydrazine, Hydrazide und Hydrazone. Journal of Cancer Research and Clinical Oncology 97:2, pages 97-108.
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J. Kleineke, H. Peters & H.D. So¨ling. (1979) Inhibition of hepatic gluconeogenesis by phenethylhydrazine (phenelzine). Biochemical Pharmacology 28:8, pages 1379-1389.
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S.D. Nelson, J.A. Hinson & J.R. Mitchell. (1976) Application of chemical ionization mass spectrometry and the twin-ion technique to better define a mechanism in acetylhydrazine toxicity. Biochemical and Biophysical Research Communications 69:4, pages 900-907.
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Charles O. Knowles & Shawky A. Aziz. (1974) Toxicity of benzoyl chloride (2,4,6-trichlorophenyl) hydrazone (banamite) and potential metabolites to twospotted spider mites and potency as inhibitor of rat liver monoamine oxidase. Bulletin of Environmental Contamination and Toxicology 12:2, pages 158-160.
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