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Drug Metabolism Reviews Volume 3, 1975 - Issue 1
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Research Article

Metabolism of Brain Acetylcholine and Its Modification by Drugs

Pavel D. Hrdina Department of Pharmacology Faculty of Medicine, University of Ottawa Ottawa, Ontario, Canada, KIN 6N5
Pages 89-129 | Published online: 22 Sep 2008

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David H. Chatfield. (1976) Disposition and Metabolism of Some Nitrofurylthiazoles Possessing Antiparasitic Activity. Xenobiotica 6:8, pages 509-520.
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Mostofa Jamal, Kiyoshi Ameno, Weihuan Wang, Mitsuru Kumihashi, Setsuko Ameno, Uekita Ikuo, Azuma Shinji & Iwao Ijiri. (2005) Inhibition of acetaldehyde metabolism decreases acetylcholine release in medial frontal cortex of freely moving rats. Brain Research 1039:1-2, pages 90-96.
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Tsung-Ming Shih, David E. Lenz & Donald M. Maxwell. (1990) Effects of repeated injection of sublethal doses of soman on behavior and on brain acetylcholine and choline concentrations in the rat. Psychopharmacology 101:4, pages 489-496.
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David M. Warburton. 1989. Progress in Drug Research. Progress in Drug Research 9 41 .
Haruo Kobayashi, Akira Yuyama & Ken-Ichi Chiba. (1986) Cholinergic system of brain tissue in rats poisoned with the organophosphate, 0,0-dimethyl 0-(2,2-dichlorovinyl) phosphate. Toxicology and Applied Pharmacology 82:1, pages 32-39.
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Stanislav Tuček. (1984) Problems in the organization and control of acetylcholine synthesis in brain neurons. Progress in Biophysics and Molecular Biology 44:1, pages 1-46.
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Guy Sanfaçon & Gaston Labrecque. (1982) Ketamine is the anesthetic of choice in studies on neocortical acetylcholine release. European Journal of Pharmacology 85:3-4, pages 347-350.
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Tsung-Ming Shih. (1982) Time course effects of soman on acetylcholine and choline levels in six discrete areas of the rat brain. Psychopharmacology 78:2, pages 170-175.
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John A. Edwards & David M. Warburton. (1982) Smoking, nicotine and electrocortical activity. Pharmacology & Therapeutics 19:2, pages 147-164.
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H. Kilbinger & R. Kruel. (1981) Choline inhibits acetylcholine release via presynaptic muscarine receptors. Naunyn-Schmiedeberg's Archives of Pharmacology 316:2, pages 131-134.
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Lynn Wecker & Wolf‐D. Dettbarn. (2006) RELATIONSHIP BETWEEN CHOLINE AVAILABILITY AND ACETYLCHOLINE SYNTHESIS IN DISCRETE REGIONS OF RAT BRAIN. Journal of Neurochemistry 32:3, pages 961-967.
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H.-D. Adolphs, J. Thiele & W. VahlensieckH.-D. Adolphs, J. Thiele & W. Vahlensieck. 1979. Harnblasentumoren. Harnblasentumoren 171 202 .
Cameron B. Gundersen & Bruce D. Howard. (1978) THE EFFECTS OF BOTULINUM TOXIN ON ACETYLCHOLINE METABOLISM IN MOUSE BRAIN SLICES AND SYNAPTOSOMES. Journal of Neurochemistry 31:4, pages 1005-1013.
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Giorgio Bignami & Hanna Michałek. 1978. Psychopharmacology of Aversively Motivated Behavior. Psychopharmacology of Aversively Motivated Behavior 173 255 .
John W. Haycock & John A. Meligeni. (1977) Neurotransmitter accumulation and calcium-dependent release from different regions of rat brain. Life Sciences 21:12, pages 1837-1843.
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J. Bajgar, J. Herink & V. Hrdina. (1977) Changes of acetylcholinesterase activity in the brain following septal lesions in the rat. Neuroscience 2:4, pages 635-639.
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Dean R. Haubrich & Thomas J. Chippendale. (1977) Regulation of acetylcholine synthesis in nervous tissue. Life Sciences 20:9, pages 1465-1478.
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R.B. Rastogi, P.D. Hrdina, T. Dubas & R.L. Singhal. (1977) Alterations of brain acetylcholine metabolism during neonatal hyperthyroidism. Brain Research 123:1, pages 188-192.
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W. B. Stavinoha, A. T. Modak & S. T. Weintraub. (2006) RATE OF ACCUMULATION OF ACETYLCHOLINE IN DISCRETE REGIONS OF THE RAT BRAIN AFTER DICHLORVOS TREATMENT. Journal of Neurochemistry 27:6, pages 1375-1378.
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Frank Welsch. (1976) Uptake of acetylcholine by human placenta fragments and slices from guinea pig and rat placenta. Biochemical Pharmacology 25:1, pages 81-89.
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R.B. Rastogi, R.L. Singhal & P.D. Hrdina. (1975) Influence of desmethylimipramine on some neurochemical alterations during experimental hypothyroidism. Neuropharmacology 14:10, pages 747-753.
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A. Nistri, Angiola M. De Bellis & Emanuela Cammelli. (1975) Drug-induced changes in behaviour and ganglionic acetylcholine concentration of the leech. Neuropharmacology 14:8, pages 565-569.
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