Citations (96)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (12)
Christoffel Petrus Stephanus Badenhorst, Elardus Erasmus, Rencia van der Sluis, Carla Nortje & Alberdina Aike van Dijk. (2014) A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids. Drug Metabolism Reviews 46:3, pages 343-361.
Read now
Read now
Bianca Rocca, Alfredo Dragani & Francesca Pagliaccia. (2013) Identifying determinants of variability to tailor aspirin therapy. Expert Review of Cardiovascular Therapy 11:3, pages 365-379.
Read now
Read now
Brian L. Pearlman & Rashi Gambhir. (2009) Salicylate Intoxication: A Clinical Review. Postgraduate Medicine 121:4, pages 162-168.
Read now
Read now
Wei Tang. (2007) Drug metabolite profiling and elucidation of drug-induced hepatotoxicity. Expert Opinion on Drug Metabolism & Toxicology 3:3, pages 407-420.
Read now
Read now
J. I. Macdonald, R. G. Dickinson, R. S. Reid, R. W. Edom, A. R. King & R. K. Verbeeck. (1991) Identification of a hydroxy metabolite of diflunisal in rat and human urine. Xenobiotica 21:11, pages 1521-1533.
Read now
Read now
D. K. Patel, L. J. Notarianni & P. N. Bennett. (1990) Comparative metabolism of high doses of aspirin in man and rat. Xenobiotica 20:8, pages 847-854.
Read now
Read now
TaiC. Kwong. (1987) Analysis of Acetylsalicylic Acid and Its Metabolites by Liquid Chromatography. Journal of Liquid Chromatography 10:2-3, pages 305-321.
Read now
Read now
Tai C. Kwong & Steven J. Soldin. (1987) Salicylate Measurement: Clinical Usefulness and Methodology. CRC Critical Reviews in Clinical Laboratory Sciences 25:2, pages 137-159.
Read now
Read now
A. J. Hutt, J. Caldwell & R. L. Smith. (1986) The metabolism of aspirin in man: a population study. Xenobiotica 16:3, pages 239-249.
Read now
Read now
Ihor Bekersky. (1983) Use of the Isolated Perfused Kidney as a Tool in Drug Disposition Studies. Drug Metabolism Reviews 14:5, pages 931-960.
Read now
Read now
A. J. Hutt, J. Caldwell & R. L. Smith. (1982) The metabolism of [carboxyl-C]aspirin in man. Xenobiotica 12:10, pages 601-610.
Read now
Read now
Melvin E. Andersen & Michael J. McKenna. (1981) Saturable Metabolism and its Relationship to Toxicity. CRC Critical Reviews in Toxicology 9:2, pages 105-150.
Read now
Read now
Articles from other publishers (84)
Chan Suen Wah, Chan Chi Keung, Ng Yau Tak, Lui Chun Tat & Fung Hin Tat. (2022) Prediction rule of supratherapeutic peak serum salicylate level in poisoning patients attending emergency departments. Hong Kong Journal of Emergency Medicine 30:6, pages 358-368.
Crossref
Crossref
Younes Zebbiche, Abderrahmane Kori Yahia, Nour El Yakine Keraghel, Fiala Sarah, Chebli Akli Islam & Achouri Mohammed Yacine. (2023) Validation of a simple spectrophotometric method for the rapid determination of salicylates in plasma. Journal of Pharmacological and Toxicological Methods 124, pages 107475.
Crossref
Crossref
Ellen M.E. Sykes, Dawn White, Sydney McLaughlin & Ayush Kumar. (2023) Salicylic acids and pathogenic bacteria: new perspectives on an old compound. Canadian Journal of Microbiology.
Crossref
Crossref
Rencia van der Sluis & Kathleen M. Knights. 2023. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Shashwati Mathurkar, Preet Singh, Kavitha Kongara & Paul Chambers. (2018) Pharmacokinetics of Salicylic Acid Following Intravenous and Oral Administration of Sodium Salicylate in Sheep. Animals 8:7, pages 122.
Crossref
Crossref
K.M. Knights. 2018. Comprehensive Toxicology. Comprehensive Toxicology
517
540
.
Jian-Ping Li, Jian-Ming Guo, Er-Xin Shang, Zhen-Hua Zhu, Yang Liu, Bu-Chang Zhao, Jing Zhao, Zhi-Shu Tang & Jin-Ao Duan. (2017) Quantitative determination of five metabolites of aspirin by UHPLC–MS/MS coupled with enzymatic reaction and its application to evaluate the effects of aspirin dosage on the metabolic profile. Journal of Pharmaceutical and Biomedical Analysis 138, pages 109-117.
Crossref
Crossref
Nicholas W. Russo, Giovanna Petrucci & Bianca Rocca. (2016) Aspirin, stroke and drug-drug interactions. Vascular Pharmacology 87, pages 14-22.
Crossref
Crossref
Priscilla Aparecida Tártari Pereira, Daniel Bini, Fernanda Bovo, Lucia Helena Faccioli & Marta Chagas Monteiro. (2016) Neutrophils influx and proinflammatory cytokines inhibition by sodium salicylate, unlike aspirin, in Candida albicans-induced peritonitis model. Folia Microbiologica 61:4, pages 337-346.
Crossref
Crossref
Karsten Schrör. 2016. Acetylsalicylic Acid. Acetylsalicylic Acid
51
166
.
Nicholas Bodor & Peter Buchwald. 2012. Retrometabolic Drug Design and Targeting. Retrometabolic Drug Design and Targeting
77
258
.
Alexander V. LyubimovKathleen M. Knights & John O. Miners. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
16
.
Martin J O'Connell & Nigel R Webster. (1990) Hyperoxia and salicylate metabolism in rats. Journal of Pharmacy and Pharmacology 42:3, pages 205-206.
Crossref
Crossref
K.M. Knights & D.A. Vessey. 2010. Comprehensive Toxicology. Comprehensive Toxicology
459
483
.
Karsten Schrör. 2008. Acetylsalicylic Acid. Acetylsalicylic Acid
33
127
.
John O. Miners & Richard O. Day. (2007) Relationships between the adverse effects of drugs and genetic polymorphism in genes encoding drug metabolizing enzymes. British Journal of Clinical Pharmacology 63:3, pages 380-381.
Crossref
Crossref
E. Jähnchen & F.-J. Neumann. 2004. Herzkrankheiten. Herzkrankheiten
897
910
.
B. Schmid, C. Biegert, I. Kötter & L. Heide. 2002. Phytopharmaka VII. Phytopharmaka VII
93
100
.
Jodi L. DeBlassio, Mitchell A. deLong, Uta Glufke, Raviraj Kulathila, Kathleen A. Merkler, John C. Vederas & David J. Merkler. (2000) Amidation of Salicyluric Acid and Gentisuric Acid: A Possible Role for Peptidylglycine α-Amidating Monooxygenase in the Metabolism of Aspirin. Archives of Biochemistry and Biophysics 383:1, pages 46-55.
Crossref
Crossref
Burkhard Hinz, Volker Kraus, Andreas Pahl & Kay Brune. (2000) Salicylate Metabolites Inhibit Cyclooxygenase-2-Dependent Prostaglandin E2 Synthesis in Murine Macrophages. Biochemical and Biophysical Research Communications 274:1, pages 197-202.
Crossref
Crossref
Stefan Heitmeier & Gottfried Blaschke. (1999) Direct assay of nonopioid analgesics and their metabolites in human urine by capillary electrophoresis and capillary electrophoresis?mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 721:1, pages 109-125.
Crossref
Crossref
Helmut Roskamm & H. ReindellCh. Gohlke-Bärwolf, E. Jähnchen & D. Kalusche. 1996. Herzkrankheiten. Herzkrankheiten
1301
1339
.
Donald A. Vessey & Jie Hu. (2006) Isolation from bovine liver mitochondria and characterization of three distinct carboxylic acid:CoA ligases with activity toward xenobiotics. Journal of Biochemical Toxicology 10:6, pages 329-337.
Crossref
Crossref
Shigehiro Ohdo, Nobuya Ogawa & Jian Guo Song. (1995) Chronopharmacological study of acetylsalicylic acid in mice. European Journal of Pharmacology: Environmental Toxicology and Pharmacology 293:2, pages 151-157.
Crossref
Crossref
A. Doenicke. 1995. Anästhesiologie. Anästhesiologie
93
124
.
P. J. Jastreboff & J. F. Brennan. (1994) Alleviation of mortality induced by salicylate and stress. Experientia 50:5, pages 469-474.
Crossref
Crossref
M. Lázníček & A. Lázníčková. (1994) Kidney and liver contributions to salicylate metabolism in rats. European Journal of Drug Metabolism and Pharmacokinetics 19:1, pages 21-26.
Crossref
Crossref
T.B. Vree, E.W.J. van Ewijk-Beneken Kolmer, C.P.W.G.M. Verwey-van Wissen & Y.A. Hekster. (1994) Direct gradient reversed-phase high-performance liquid chromatographic determination of salicylic acid, with the corresponding glycine and glucuronide conjugates in human plasma and urine. Journal of Chromatography B: Biomedical Sciences and Applications 652:2, pages 161-170.
Crossref
Crossref
A. Jaeger, C. Berton & J. Kempf. 1994. Yearbook of Intensive Care and Emergency Medicine 1994. Yearbook of Intensive Care and Emergency Medicine 1994
707
715
.
John M. Kovarik, Edgar A. Mueller, Martin Gaber, Atholl Johnston & Eberhard Jähnchen. (2013) Pharmacokinetics of Cyclosporine and Steady‐State Aspirin During Coadministration. The Journal of Clinical Pharmacology 33:6, pages 513-521.
Crossref
Crossref
C. Bassleer, Y. Henrotin & P. Franchimont. (2012) Effects of Ximoprofen and Acetylsalicylic Acid on Human Articular Chondrocytes in 3-Dimensional Culture. Drug Investigation 5:1, pages 11-18.
Crossref
Crossref
F. M. Macdonald & V. M. Lingard. 1993. Dictionary of Analytical Reagents. Dictionary of Analytical Reagents
518
619
.
Paola Bertocchi, Dario D'Ottavio, Maria E. Evangelisti, Marco Mascini & Giuseppe Palleschia. (1992) A flow-through system for the determination of salicylate in blood. Clinica Chimica Acta 207:3, pages 205-213.
Crossref
Crossref
A Viani, G Rizzo, M Carrai & GM Pacifici. (2012) The effect of ageing on plasma albumin and plasma protein binding of diazepam, salicylic acid and digitoxin in healthy subjects and patients with renal impairment.. British Journal of Clinical Pharmacology 33:3, pages 299-304.
Crossref
Crossref
C. Bassleer, Y. Henrotin & P. Franchimont. (1992) Effects of sodium naproxen on differentiated human chondrocytes cultivated in clusters. Clinical Rheumatology 11:1, pages 60-65.
Crossref
Crossref
A. Doenicke. 1992. Anästhesiologie. Anästhesiologie
88
115
.
J. Shen, S. Wanwimolrak, R. D. Purves, E. G. McQueen & M. S. Roberts. (1991) Model representation of salicylate pharmacokinetics using unbound plasma salicylate concentrations and metabolite urinary excretion rates following a single oral dose. Journal of Pharmacokinetics and Biopharmaceutics 19:5, pages 575-595.
Crossref
Crossref
Hisham Y. Abdallah, Michael Mayersohn & Kenneth A. Conrad. (2013) The Influence of Age on Salicylate Pharmacokinetics in Humans. The Journal of Clinical Pharmacology 31:4, pages 380-387.
Crossref
Crossref
D.K. Patel, A. Ogunbona, L.J. Notarianni & P.N. Bennett. (2016) Depletion of Plasma Glycine and Effect of Glycine by Mouth on Salicylate Metabolism During Aspirin Overdose. Human & Experimental Toxicology 9:6, pages 389-395.
Crossref
Crossref
D.K. Patel, A. Hesse, A. Ogunbona, L.J. Notarianni & P.N. Bennett. (2016) Metabolism of Aspirin after Therapeutic and Toxic Doses. Human & Experimental Toxicology 9:3, pages 131-136.
Crossref
Crossref
J. Elks & C. R. Ganellin. 1990. Dictionary of Drugs. Dictionary of Drugs
617
672
.
J. F. Brennan & P. J. Jastreboff. (1989) Interaction of salicylate and noise results in mortality of rats. Experientia 45:8, pages 731-734.
Crossref
Crossref
Kwok Keung. Shiu, Ronald. Chemerika & D. Jed. Harrison. (2002) Effects of added plasticizer on redox ion charge transport in quaternized poly(vinylpyridine) films. Analytical Chemistry 61:6, pages 570-573.
Crossref
Crossref
N. A. Chaniotakis, S. B. Park & Mark E. Meyerhoff. (2002) Salicylate-selective membrane electrode based on tin(IV)-tetraphenylporphyrin. Analytical Chemistry 61:6, pages 566-570.
Crossref
Crossref
Suresh Mallikaarjun, John H. Wood & H.Thomas Karnes. (1989) High-performance liquid chromatographic method for the determination of salicylic acid and its metabolites in urine by direct injection. Journal of Chromatography B: Biomedical Sciences and Applications 493, pages 93-104.
Crossref
Crossref
Richard O. Day, Daniel E. Furst, Sydney H. Dromgoole & Harold E. Paulus. (2006) Changes in salicylate serum concentration and metabolism during chronic dosing in normal volunteers. Biopharmaceutics & Drug Disposition 9:3, pages 273-283.
Crossref
Crossref
D. Jacobsen, E. Wiik-Larsen & J.E. Bredesen. (2016) Haemodialysis or Haemoperfusion in Severe Salicylate Poisoning?. Human Toxicology 7:2, pages 161-163.
Crossref
Crossref
Joseph Markenson. (1988) A panel discussion on the safety of nonsteroidal antiinflammatory drugs. Seminars in Arthritis and Rheumatism 17:3, pages 1-6.
Crossref
Crossref
M.A. Koupparis & P.I. Anagnostopoulou. (1988) Automated flow injection determination of salicylates using Trinder reaction for clinical analysis, assays and dissolution studies of formulations. Journal of Pharmaceutical and Biomedical Analysis 6:1, pages 35-46.
Crossref
Crossref
S M Burris, C M Smith2nd2nd, G H Rao & J G White. (1987) Aspirin treatment reduces platelet resistance to deformation.. Arteriosclerosis: An Official Journal of the American Heart Association, Inc. 7:4, pages 385-388.
Crossref
Crossref
JO Miners, N. Grgurinovich, AG Whitehead, RA Robson & DJ Birkett. (1986) Influence of gender and oral contraceptive steroids on the metabolism of salicylic acid and acetylsalicylic acid.. British Journal of Clinical Pharmacology 22:2, pages 135-142.
Crossref
Crossref
David J. Greenblatt, Darrell R. Abernethy, Harold G. Boxenbaum, Rita Matlis, Hermann R. Ochs, Jerold S. Harmatz & Richard I. Shader. (2005) Influence of age, gender, and obesity on salicylate kinetics following single doses of aspirin. Arthritis & Rheumatism 29:8, pages 971-980.
Crossref
Crossref
Maikel Raghoebar, Fanny Vrancx & Cees A. M. Van Ginneken. (2006) A pharmacokinetic approach to the establishment of biopharmaceutic characteristics of different acetylsalicylic acid formulations in man. Biopharmaceutics & Drug Disposition 7:2, pages 183-195.
Crossref
Crossref
PC Ho, EJ Triggs, DW Bourne & VJ Heazlewood. (2012) The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites.. British Journal of Clinical Pharmacology 19:5, pages 675-684.
Crossref
Crossref
E. Zylber-Katz, L. Granit & M. Levy. (1985) Plasma protein binding of dipyrone metabolites in man. European Journal of Clinical Pharmacology 29:1, pages 67-71.
Crossref
Crossref
Lars Borgström, Bo Ekman, Hans Larsson, Ido Leden, Åke Lindahl, Arne Melander & Elisabeth Wålin‐boll. (2006)
In vitro
and
in vivo
evaluation of controlled‐release and enteric‐coated formulations of sodium salicylate
. Biopharmaceutics & Drug Disposition 5:3, pages 261-272.
Crossref
Crossref
RA Seymour, FM Williams, A Ward & MD Rawlins. (2012) Aspirin metabolism and efficacy in postoperative dental pain.. British Journal of Clinical Pharmacology 17:6, pages 697-701.
Crossref
Crossref
D.R. Varma & T.L. Yue. (2012) Influence of age, sex, pregnancy and protein‐calorie malnutrition on the pharmacokinetics of salicylate in rats. British Journal of Pharmacology 82:1, pages 241-248.
Crossref
Crossref
G.H.R. Rao, E. Radha, G.J. Johnson & J.G. White. (1984) Enteric-coated aspirin, platelet cyclooxygenase activity and function. Prostaglandins, Leukotrienes and Medicine 13:3, pages 341-347.
Crossref
Crossref
R. Stephen Porter. (2017) Factors Determining Efficacy of NSAIDS. Drug Intelligence & Clinical Pharmacy 18:1, pages 42-51.
Crossref
Crossref
K.D. Rainsford. 1984. Aspirin and the Salicylates. Aspirin and the Salicylates
32
66
.
R.James O'kruk, Michael A. Adams & Richard B. Philp. (1984) Rapid and sensitive determination of acetylsalicylic acid and its metabolites using reversed-phase high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 310, pages 343-352.
Crossref
Crossref
Zdena Trnavsk� & Karel Trnavsk�. (1984) Plasma protein binding and interaction studies with piroxicam. Naunyn-Schmiedeberg's Archives of Pharmacology 327:1, pages 81-85.
Crossref
Crossref
William M. Bennett, George R. Aronoff, Gail Morrison, Thomas A. Golper, Joseph Pulliam, Marsha Wolfson & Irwin Singer. (1983) Drug Prescribing in Renal Failure: Dosing Guidelines for Adults. American Journal of Kidney Diseases 3:3, pages 155-193.
Crossref
Crossref
Shamsul K. Bakar & Sarfaraz Niazi. (1983) Effect of Water Deprivation on Aspirin Disposition Kinetics. Journal of Pharmaceutical Sciences 72:9, pages 1030-1034.
Crossref
Crossref
R.B. Philp & M.L. Paul. (1983) Low-dose aspirin (ASA) renders human platelets more vulnerable to inhibition of aggregation by prostacyclin (PGI2). Prostaglandins, Leukotrienes and Medicine 11:2, pages 131-142.
Crossref
Crossref
. (1983) Orthopedic surgery. Arthritis & Rheumatism 26:3, pages 359-436.
Crossref
Crossref
Stephen T. Ingalls, John F. Schwerkoske, Walter B. Forman & Charles L. Hoppel. (1983) Rapid and sensitive method for the determination of salicylic acid in serum by reversed-phase ion-pair high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 274, pages 366-371.
Crossref
Crossref
Z. Trnavsk� & K. Trnavsk�. (1983) Sex differences in the pharmacokinetics of salicylates. European Journal of Clinical Pharmacology 25:5, pages 679-682.
Crossref
Crossref
J. C. Greenaway, Thomas H. Shepard, Alan G. Fantel & Mont R. Juchau. (2005) Sodium salicylate teratogenicity in vitro. Teratology 26:2, pages 167-171.
Crossref
Crossref
G.H.R. Rao, K.R. Reddy & J.G. White. (1982) Effect of acetaminophen and salicylate on aspir-ininduced indibition of human platelet cyclo-oxygenase. Prostaglandins, Leukotrienes and Medicine 9:1, pages 109-115.
Crossref
Crossref
RA Seymour & MD Rawlins. (2012) Efficacy and pharmacokinetics of aspirin in post‐operative dental pain.. British Journal of Clinical Pharmacology 13:6, pages 807-810.
Crossref
Crossref
B. Brantmark, E. W�hlin-Boll & A. Melander. (1982) Bioavailability of acetylsalicylic acid and salicylic acid from rapid-and slow-release formulations, and in combination with dipyridamol. European Journal of Clinical Pharmacology 22:4, pages 309-314.
Crossref
Crossref
Patrick B. Costello, Floyd A. Green & Chan Y. Jung. (2005) Free versus bound salicylate concentration in adults and children with chronic inflammatory joint disease. Arthritis & Rheumatism 25:1, pages 32-37.
Crossref
Crossref
B. Brantmark, U. Hedner, A. Melander & E. Wåhlin-Boll. (1981) SALICYLATE INHIBITION OF ANTIPLATELET EFFECT OF ASPIRIN. The Lancet 318:8259, pages 1349.
Crossref
Crossref
C. Blanchet-Bardon, A. Puissant & M. Lutzner. (1981) ETRETINATE IN BOWENOID PAPULOSIS. The Lancet 318:8259, pages 1348-1349.
Crossref
Crossref
F. Jamali, T. Khazainia & M.Rafiee Therani. (1981) Absorption rate limited metabolism of salicylate in man: a consideration in bioavailability assessment. International Journal of Pharmaceutics 9:3, pages 221-231.
Crossref
Crossref
Thorsteinn Loftsson, James J. Kaminski & Nicholas Bodor. (1981) Improved delivery through biological membranes VIII: Design, synthesis, and in vivo testing of true prodrugs of aspirin. Journal of Pharmaceutical Sciences 70:7, pages 743-749.
Crossref
Crossref
Ralph E. Kauffman. (1981) The Clinical Interpretation and Application of Drug Concentration Data. Pediatric Clinics of North America 28:1, pages 35-45.
Crossref
Crossref
E. W�hlin-Boll, B. Brantmark, A. Hanson, A. Melander & C. Nilsson. (1981) High-pressure liquid chromatographic determination of acetylsalicylic acid, salicylic acid, diflunisal, indomethacin, indoprofen and indobufen. European Journal of Clinical Pharmacology 20:5, pages 375-378.
Crossref
Crossref
P. G. Wells, G. W. Moore, D. Rabin, G. R. Wilkinson, J. A. Oates & P. W. Stacpoole. (1980) Metabolic effects and pharmacokinetics of intravenously administered dichloroacetate in humans. Diabetologia 19:2, pages 109-113.
Crossref
Crossref
G Levy. (2012) Clinical pharmacokinetics of salicylates: a re‐assessment.. British Journal of Clinical Pharmacology 10:S2.
Crossref
Crossref
Svein Øie & Leslie Z. Benet. 1980.
277
287
.
Z. Trnavsk� & K. Trnavsk�. (1980) Characterization of salicylate binding to synovial fluid and plasma protein in patients with rheumatoid arthritis. European Journal of Clinical Pharmacology 18:5, pages 403-406.
Crossref
Crossref