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Research Article

Vehicle Effects in Percutaneous Absorption

Pages 207-222 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Catherine Champmartin, Lisa Chedik, Fabrice Marquet & Frédéric Cosnier. (2022) Occupational exposure assessment with solid substances: choosing a vehicle for in vitro percutaneous absorption experiments. Critical Reviews in Toxicology 52:4, pages 294-316.
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Jim E. Riviere, James D. Brooks, James L. Yeatts & Elisha L. Koivisto. (2010) Surfactant Effects on Skin Absorption of Model Organic Chemicals: Implications for Dermal Risk Assessment Studies. Journal of Toxicology and Environmental Health, Part A 73:11, pages 725-737.
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M. E. Morales, B. Clarés, M. López-Viota & M. A. Ruiz. (2009) Preparation, characterization, and in vitro release of new transdermal methimazole as alternative to oral delivery. Drug Delivery 16:1, pages 1-10.
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B. B. Michniak, M. R. Player, D. A. Godwin & J. W. Sowell. (1995) Investigation of enhancer structure activity relationships in congeners of 2-(1-nonyl)-1,3-dioxolane. Drug Delivery 2:2, pages 117-122.
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MichaelF. Hughes, SurendraP. Shrivastava, MarthaR. Sumler, BrendaC. Edwards, JohnH. Goodwin, P. V. Shah, HenryL. Fisher & LarryL. Hall. (1992) Dermal absorption of chemicals: Effect of application of chemicals as a solid, aqueous paste, suspension, or in volatile vehicle. Journal of Toxicology and Environmental Health 37:1, pages 57-71.
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Esmail M. Niazy, Abdulla M. Molokhia & Abubakr S. El-Gorashi. (1990) Effect of Vehicle and Drug Concentration on transdermal delivery of Dihydroergotamine using excised Animal Skin. Drug Development and Industrial Pharmacy 16:10, pages 1697-1715.
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Articles from other publishers (54)

Em-on Chaiprateep, Sabrina Wiemann, Ralph W. Eckert, Christian Raab, Soma Sengupta & Cornelia M. Keck. (2023) Influence of Dose, Particle Size and Concentration on Dermal Penetration Efficacy of Curcumin. Pharmaceutics 15:11, pages 2645.
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Cornelia M. Keck, Em-on Chaiprateep, Henriette Dietrich & Soma Sengupta. (2022) Influence of Mechanical Skin Treatments on Dermal Penetration Efficacy of Active Ingredients. Pharmaceutics 14:9, pages 1788.
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Sabrina Wiemann & Cornelia M. Keck. (2022) Particle-Assisted Dermal Penetration—A Simple Formulation Strategy to Foster the Dermal Penetration Efficacy. Pharmaceutics 14:5, pages 1039.
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Cornelia M. Keck, Ayat Abdelkader, Olga Pelikh, Sabrina Wiemann, Vasudha Kaushik, David Specht, Ralph W. Eckert, Reem M. Alnemari, Henriette Dietrich & Jana Brüßler. (2022) Assessing the Dermal Penetration Efficacy of Chemical Compounds with the Ex-Vivo Porcine Ear Model. Pharmaceutics 14:3, pages 678.
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Rodrigo Collina Romanhole, Ana Laura Masquetti Fava, Louise Lacalendola Tundisi, Lucas Malvezzi de Macedo, Érica Mendes dos Santos, Janaína Artem Ataide & Priscila Gava Mazzola. (2020) Unplanned absorption of sunscreen ingredients: Impact of formulation and evaluation methods. International Journal of Pharmaceutics 591, pages 120013.
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Anukta Datta, Velidanda S. Tanmay, Grace X. Tan, Geoffrey W. Reynolds, Sumanth N. Jamadagni & Ronald G. Larson. (2020) Characterizing the rheology, slip, and velocity profiles of lamellar gel networks. Journal of Rheology 64:4, pages 851-862.
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Xiaoying Hui & Howard I. Maibach. 2020. Skin Decontamination. Skin Decontamination 25 44 .
Magnus Lundborg, Christian L. Wennberg, Ali Narangifard, Erik Lindahl & Lars Norlén. (2018) Predicting drug permeability through skin using molecular dynamics simulation. Journal of Controlled Release 283, pages 269-279.
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Ryan F. Donnelly & Thakur Raghu Raj SinghGary P.J. Moss. 2015. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery. Novel Delivery Systems for Transdermal and Intradermal Drug Delivery 1 40 .
Gary P. Moss, Darren R. Gullick & Simon C. WilkinsonGary P. Moss, Darren R. Gullick & Simon C. Wilkinson. 2015. Predictive Methods in Percutaneous Absorption. Predictive Methods in Percutaneous Absorption 1 24 .
Sarfaraz K. Niazi. 2014. Handbook of Bioequivalence Testing. Handbook of Bioequivalence Testing 756 787 .
Carol M. Gee, Adam C. Watkinson, Joseph A. Nicolazzo & Barrie C. Finnin. (2014) The Effect of Formulation Excipients on the Penetration and Lateral Diffusion of Ibuprofen on and within the Stratum Corneum Following Topical Application to Humans. Journal of Pharmaceutical Sciences 103:3, pages 909-919.
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Daniela Karadzovska & Jim E. Riviere. (2013) Assessing vehicle effects on skin absorption using artificial membrane assays. European Journal of Pharmaceutical Sciences 50:5, pages 569-576.
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Xiaoying Hui, Sonia Lamel, Peter Qiao & Howard I. Maibach. (2012) Isolated human and animal stratum corneum as a partial model for the 15 steps of percutaneous absorption: emphasizing decontamination, part II. Journal of Applied Toxicology 33:3, pages 173-182.
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Daniela Karadzovska, James D. Brooks, Nancy A. Monteiro-Riviere & Jim E. Riviere. (2013) Predicting skin permeability from complex vehicles. Advanced Drug Delivery Reviews 65:2, pages 265-277.
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Jim E. Riviere & James D. Brooks. (2011) Predicting Skin Permeability from Complex Chemical Mixtures: Dependency of Quantitative Structure Permeation Relationships on Biology of Skin Model Used. Toxicological Sciences 119:1, pages 224-232.
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Ronald E. Baynes & Jim E. Riviere. 2010. Principles and Practice of Mixtures Toxicology. Principles and Practice of Mixtures Toxicology 349 376 .
P. C. Mills. (2006) Vehicle Effects on the In Vitro Penetration of Testosterone through Equine Skin. Veterinary Research Communications 31:2, pages 227-233.
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E.-S. A. Ibrahim, M.A. Hassan, M.M. El-Mahdy & A.S. Mohamed. (2007) Formulation and evaluation of quercetin in certain dermatological preparations. Journal of Drug Delivery Science and Technology 17:6, pages 431-436.
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Paul C. Mills, Beatrice M. Magnusson & Sheree E. Cross. (2006) The effects of vehicle and region of application on in vitro penetration of testosterone through canine skin. The Veterinary Journal 171:2, pages 276-280.
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Jim E. Riviere & James D. Brooks. (2005) Predicting skin permeability from complex chemical mixtures. Toxicology and Applied Pharmacology 208:2, pages 99-110.
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Jim Riviere. 2005. Dermal Absorption Models in Toxicology and Pharmacology. Dermal Absorption Models in Toxicology and Pharmacology 283 303 .
Paul C. Mills, Beatrice M. Magnusson & Sheree E. Cross. (2005) Effects of vehicle and region of application on absorption of hydrocortisone through canine skin. American Journal of Veterinary Research 66:1, pages 43-47.
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Frank Z. Stanczyk, Richard J. Paulson & Subir Roy. (2005) Percutaneous administration of progesterone: blood levels and endometrial protection. Menopause 12:2, pages 232-237.
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Jim Riviere. 2004. Dermatotoxicology, Sixth Edition. Dermatotoxicology, Sixth Edition 29 40 .
PC MILLS, BM MAGNUSSON & SE CROSS. (2008) Effect of solute lipophilicity on penetration through canine skin. Australian Veterinary Journal 81:12, pages 752-755.
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P. C. Mills, B. M. Magnusson & S. E. Cross. (2003) The effect of solute lipophilicity on penetration through feline skin. Journal of Veterinary Pharmacology and Therapeutics 26:4, pages 311-314.
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P. T. Reeves. 2003. Encyclopedia of Agrochemicals. Encyclopedia of Agrochemicals.
Cristina D Röpke, Telma M Kaneko, Renata M Rodrigues, Vanessa V da Silva, Sonia Barros, Tânia C.H Sawada, Massuo J Kato & Silvia B.M Barros. (2002) Evaluation of percutaneous absorption of 4-nerolidylcathecol from four topical formulations. International Journal of Pharmaceutics 249:1-2, pages 109-116.
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Patrick L. Williams & Jim E. Riviere. (1995) A Biophysically Based Dermatopharmacokinetic Compartment Model for Quantifying Percutaneous Penetration and Absorption of Topically Applied Agents. I. Theory. Journal of Pharmaceutical Sciences 84:5, pages 599-608.
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S.A.M. Hotchkiss, J.M. Miller & J. Caldwell. (1992) Percutaneous absorption of benzyl acetate through rat skin in vitro. 2. Effect of vehicle and occlusion. Food and Chemical Toxicology 30:2, pages 145-153.
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