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Research Article

Metabolism and Pharmacokinetics of Theophylline in Human Neonates, Children, and Adults

Pages 295-335 | Published online: 22 Sep 2008

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Yejin Esther Yun & Andrea N. Edginton. (2019) Model qualification of the PK-Sim® pediatric module for pediatric exposure assessment of CYP450 metabolized compounds. Journal of Toxicology and Environmental Health, Part A 82:14, pages 789-814.
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Vali Zare-Shahabadi, Mojtaba Shamsipur, Bahram Hemmatenejad & Morteza Akhond. (2010) Simultaneous Determination of Guaifenesin and Theophylline by Chemometrics Methods. Analytical Letters 43:4, pages 687-700.
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Articles from other publishers (29)

Katarzyna Wójcik-Pszczoła, Małgorzata Szafarz, Krzysztof Pociecha, Karolina Słoczyńska, Kamil Piska, Paulina Koczurkiewicz-Adamczyk, Natalia Kocot, Grażyna Chłoń-Rzepa, Elżbieta Pękala & Elżbieta Wyska. (2022) In silico and in vitro ADME-Tox analysis and in vivo pharmacokinetic study of representative pan-PDE inhibitors from the group of 7,8-disubstituted derivatives of 1,3-dimethyl-7H-purine-2,6-dione. Toxicology and Applied Pharmacology 457, pages 116318.
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Jegen Kandasamy & Waldemar A. Carlo. 2022. Goldsmith's Assisted Ventilation of the Neonate. Goldsmith's Assisted Ventilation of the Neonate 408 423.e7 .
Bingnan Ren, Jing Geng, Yu Wang & Pei Wang. (2021) Emission and ecological risk of pharmaceuticals and personal care products affected by tourism in Sanya City, China. Environmental Geochemistry and Health 43:8, pages 3083-3097.
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Xiaomei I. Liu, John N. den Anker, Gilbert J. Burckart & André Dallmann. (2021) Evaluation of Physiologically Based Pharmacokinetic Models to Predict the Absorption of BCS Class I Drugs in Different Pediatric Age Groups. The Journal of Clinical Pharmacology 61:S1.
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Reem B. Youssef, Marwa A. Fouad & Asmaa A. El-Zaher. (2020) Bioanalytical Study of the Effect of Lycopene on the Pharmacokinetics of Theophylline in Rats. Pharmaceutical Chemistry Journal 53:11, pages 1053-1058.
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Million A. Tegenge & Iftekhar Mahmood. (2018) Age- and Bodyweight-dependent Allometric Exponent Model for Scaling Clearance and Maintenance Dose of Theophylline From Neonates to Adults. Therapeutic Drug Monitoring 40:5, pages 635-641.
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Lin Xue, Qiuliyang Yu, Rudolf Griss, Alberto Schena & Kai Johnsson. (2017) Bioluminescent Antibodies for Point-of-Care Diagnostics. Angewandte Chemie International Edition 56:25, pages 7112-7116.
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Lin Xue, Qiuliyang Yu, Rudolf Griss, Alberto Schena & Kai Johnsson. (2017) Bioluminescent Antibodies for Point-of-Care Diagnostics. Angewandte Chemie 129:25, pages 7218-7222.
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Jegen Kandasamy & Waldemar A. Carlo. 2017. Assisted Ventilation of the Neonate. Assisted Ventilation of the Neonate 366 379.e5 .
Abdullah Mohammed Al-Mohizea, Mohammad Raish, Abdul Ahad, Fahad Ibrahim Al-Jenoobi & Mohd Aftab Alam. (2015) Pharmacokinetic interaction of Acacia catechu with CYP1A substrate theophylline in rabbits. Journal of Traditional Chinese Medicine 35:5, pages 588-593.
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A. Sheibani, S. Masoumi & S. Partovi. (2013) Corona discharge ion mobility spectrometry for the determination of theophylline and guaifenesin in human serum. International Journal for Ion Mobility Spectrometry 16:4, pages 259-263.
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Jane Alcorn & Patrick J. McNamara. (2002) Ontogeny of Hepatic and Renal Systemic Clearance Pathways in Infants. Clinical Pharmacokinetics 41:12, pages 959-998.
Crossref
Héctor C. Goicoechea, Alejandro C. Olivieri & Arsenio Muñoz de la Peña. (1999) Determination of theophylline in blood serum by UV spectrophotometry and partial least-squares (PLS-1) calibration. Analytica Chimica Acta 384:1, pages 95-103.
Crossref
PB Larsen, L Brendstrup, L Skov & H Flachs. (2008) Aminophylline versus caffeine citrate for apnea and bradycardia prophylaxis in premature neonates. Acta Paediatrica 84:4, pages 360-364.
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J. SIDHU, E. TRIGGS, B. CHARLES, D. TUDEHOPE, P. GRAY & D. COWLEY. (2008) Individualizing aminophylline doses in premature infants using bioelectrical impedance: A non‐invasive approach. Journal of Paediatrics and Child Health 29:2, pages 113-118.
Crossref
G. Fuglsang, K. Nielsen, L. Kjeer Nielsen, F. Sennels, P. Jakobsen & T. Thelle. (1989) The Effect of Caffeine Compared with Theophylline in the Treatment of Idiopathic Apnea in Premature Infants. Acta Paediatrica 78:5, pages 786-788.
Crossref
Sharon L. Young. (2016) Drug Disposition in the Pediatric Patient. Journal of Pharmacy Practice 2:1, pages 13-20.
Crossref
W. J. A. Wijnands, T. J. Janssen, P. J. M. Guelen, T. B. Vree & T. M. C. de Witte. (1988) The influence of ofloxacin and enoxacin on the metabolic pathways of theophylline in healthy volunteers. Pharmaceutisch Weekblad 10:6, pages 272-276.
Crossref
Kojiro Matsumoto, Haruhito Kikuchi, Hisami Iri, Hiroaki Takahasi & Masuo Umino. (1988) Automated determination of drugs in serum by columnswitching high-performance liquid chromatography II. Separation of theophylline and its metabolites. Journal of Chromatography B: Biomedical Sciences and Applications 425, pages 323-330.
Crossref
B. Stavric. (1988) Methylxanthines: Toxicity to humans. 2. Caffeine. Food and Chemical Toxicology 26:7, pages 645-662.
Crossref
B. Stavric. (1988) Methylxanthines: Toxicity to humans. 3. Theobromine, paraxanthine and the combined effects of methylxanthines. Food and Chemical Toxicology 26:8, pages 725-733.
Crossref
B. Stavric. (1988) Methylxanthines: Toxicity to humans. 1. Theophylline. Food and Chemical Toxicology 26:6, pages 541-565.
Crossref
A. L Boner, G. De Stefano, G. Vallone, M. Plebani & P. Ventura. (2017) Absolute and Relative Bioavailability of a Slow Release Theophylline Preparation in Asthmatic Children. Journal of International Medical Research 15:5, pages 282-292.
Crossref
Atsutoshi Tsuji, Mitsuru Osano, Yoshiyuki Morikawa, Masaaki Sato & Takasumi Asaishi. (2007) Electrocardiographic Standard for the Diagnosis of Right Ventricular Hypertrophy in Complete Right Bundle Branch Block. Pediatrics International 29:4, pages 600-604.
Crossref
Ronald A. Jordan & Thomas F. Woolf. (1987) Basic Concepts in Drug Metabolism: Part II. The Journal of Clinical Pharmacology 27:2, pages 87-90.
Crossref
Pierre Gaudreault & Joanne Guay. (2012) Theophylline Poisoning. Medical Toxicology 1:3, pages 169-191.
Crossref
Yasuji Kasuya, Tetsuro Ohno, Noriyoshi Kubota, Hidenori Takahashi & Hiroki Hirayama. (1985) New method for bioavailability assessment of slow-release preparations of theophylline. Journal of Pharmacokinetics and Biopharmaceutics 13:6, pages 571-587.
Crossref
PA Winstanley, J Tjia, DJ Back, D Hobson & AM Breckenridge. (2012) Lack of effect of highly purified subunit influenza vaccination on theophylline metabolism.. British Journal of Clinical Pharmacology 20:1, pages 47-53.
Crossref
Michael Spino, Roger P. Chai, Alan F. Isles, Jake J. Thiessen, Angel Tesoro, Ronald Gold & Stuart M. MacLeod. (1984) Cloxacillin absorption and disposition in cystic fibrosis. The Journal of Pediatrics 105:5, pages 829-835.
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