19
Views
73
CrossRef citations to date
0
Altmetric
Research Article

Xenobiotic Metabolism by Prostaglandin Endoperoxide Synthetase

, , , &
Pages 1023-1053 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Wolfgang Dekant & Spiros Vamvakas. (1996) Biotransformation and Membrane Transport in Nephrotoxicity. Critical Reviews in Toxicology 26:3, pages 309-334.
Read now
S. J. Duthie, W. T. Melvin & M. D. Burke. (1994) Bromobenzene detoxification in the human liver-derived HepG2 cell line. Xenobiotica 24:3, pages 265-279.
Read now
William D. Flitter & Ronald P. Mason. (1990) The Horseradish Peroxidase Catalysed Oxidation of Deoxyribose Sugars. Free Radical Research Communications 9:3-6, pages 297-302.
Read now
F. Peter Guengerich. (1990) Enzymatic Oxidation of Xenobiotic Chemical. Critical Reviews in Biochemistry and Molecular Biology 25:2, pages 97-153.
Read now
Michael M. Iba. (1989) Activation of 3,3′-Dichlorobenzldlne: Enzymic Basis and Toxicological Consequences. Drug Metabolism Reviews 21:3, pages 377-400.
Read now
Peter H. Bach, James W. Bridges & Gilbert H. Mudge. (1985) Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 1. CRC Critical Reviews in Toxicology 15:3, pages 217-329.
Read now
Peter H. Bach, James W. Bridges & Gilbert H. Mudge. (1985) Chemically Induced Renal Papillary Necrosis and Upper Urothelial Carcinoma. Part 2. CRC Critical Reviews in Toxicology 15:4, pages 331-439.
Read now

Articles from other publishers (66)

Soumita Paul, Ujjal Ghosh & Mousumi Saha. 2023. Xenobiotics in Urban Ecosystems. Xenobiotics in Urban Ecosystems 69 85 .
Edward Croom. 2012. Toxicology and Human Environments. Toxicology and Human Environments 31 88 .
Ernest Hodgson. 2012. Pesticide Biotransformation and Disposition. Pesticide Biotransformation and Disposition 53 72 .
Geoffrey R Fisher & Laurence H Patterson. (1991) DNA strand breakage by peroxidase-activated mitoxantrone. Journal of Pharmacy and Pharmacology 43:1, pages 65-68.
Crossref
Clinton R. Nishida, Melody Lee & Paul R. Ortiz de Montellano. (2010) Efficient Hypoxic Activation of the Anticancer Agent AQ4N by CYP2S1 and CYP2W1. Molecular Pharmacology 78:3, pages 497-502.
Crossref
Ernest Hodgson. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 865 875 .
John A. Timbrell & Timothy C. Marrs. 2009. General and Applied Toxicology. General and Applied Toxicology.
John Timbrell. 2008. Principles of Biochemical Toxicology, Fourth Edition. Principles of Biochemical Toxicology, Fourth Edition 75 127 .
Qiong Guo, Guanghua Gao, Steven Y. Qian & Ronald P. Mason. (2004) Novel Identification of a Sulfur-Centered, Radical-Derived 5,5-Dimethyl-1-pyrroline N -Oxide Nitrone Adduct Formed from the Oxidation of DTT by LC/ELISA, LC/Electrospray Ionization-MS, and LC/Tandem MS . Chemical Research in Toxicology 17:11, pages 1481-1490.
Crossref
Harald J. J. Moonen, Jacob J. Briedé, Jan M. S. van Maanen, Jos C. S. Kleinjans & Theo M. C. M. de Kok. (2002) Generation of free radicals and induction of DNA adducts by activation of heterocyclic aromatic amines via different metabolic pathways in vitro. Molecular Carcinogenesis 35:4, pages 196-203.
Crossref
Ernest Hodgson & E. Levi Patricia. 2001. Handbook of Pesticide Toxicology. Handbook of Pesticide Toxicology 531 562 .
G. Gramss, B. Kirsche, K.-D. Voigt, Th. Günther & W. Fritsche. (1999) Conversion rates of five polycyclic aromatic hydrocarbons in liquid cultures of fifty-eight fungi and the concomitant production of oxidative enzymes. Mycological Research 103:8, pages 1009-1018.
Crossref
S. Obrecht-Pflumio, Y. Grosse, A. Pfohl-Leszkowicz & G. Dirheimer. (1996) Protection by indomethacin and aspirin against genotoxicity of ochratoxin A, particularly in the urinary bladder and kidney. Archives of Toxicology 70:3-4, pages 244-248.
Crossref
Lily Yun Xie & David Dolphin. 1994. Metalloporphyrins Catalyzed Oxidations. Metalloporphyrins Catalyzed Oxidations 269 306 .
DIANA METODIEWA & H. BRIAN DUNFORD. 1993. Atmospheric Oxidation and Antioxidants. Atmospheric Oxidation and Antioxidants 287 332 .
HILDEGARD M. SCHÜLLER, MIRIAM FALZON & JAMES B. MCMAHON. 1993. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells 255 266 .
Tammy M. Bray & James B. Kirkland. 1993. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells. Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells 165 184 .
Fazlul H. Sarkar, Gilbert Radcliff & Denis M. Callewaert. (1992) Purified prostaglandin synthase activates aromatic amines to derivatives that are mutagenic to Salmonella typhimurium. Mutation Research Letters 282:4, pages 273-281.
Crossref
Wolfgang Dekant & Spyridon Vamvakas. 1992. 297 337 .
Stan Kubow. (2005) Inhibition of isotretinoin teratogenicity by acetylsalicylic acid pretreatment in mice. Teratology 45:1, pages 55-63.
Crossref
Adnan A. Elfarra, Renee J. Duescher & Christoph M. Pasch. (1991) Mechanisms of 1,3-butadiene oxidations to butadiene monoxide and crotonaldehyde by mouse liver microsomes and chloroperoxidase. Archives of Biochemistry and Biophysics 286:1, pages 244-251.
Crossref
George J. Kaloyanides. (1991) Metabolic interactions between drugs and renal tubulo-interstitial cells: Role in nephrotoxicity. Kidney International 39:3, pages 531-540.
Crossref
M. Stiborová, Ε. Frei, H.H. Schmeiser & P. Anzenbacher. (1991) The Role of Peroxidases in the Activation of Chemical Carcinogens. Drug Metabolism and Drug Interactions 9:3-4.
Crossref
Fazlul H. Sarkar, Gilber Radcliff, Denis M. Callewaert, Lawrence J. Marnett, Thomas Eling, Diane S. Daston & William J. Caspary. (1990) Mutagenic response of mouse lymphoma cells after activation of benzidine and 2-aminofluorene with purified prostaglandin H synthase. Mutation Research/Genetic Toxicology 242:4, pages 319-328.
Crossref
Susan M. Lunte, Donna M. Radzik & Peter T. Kissingers. (1990) An Introduction to the Study of Xenobiotic Metabolism Using Electroanalytical Techniques. Journal of Pharmaceutical Sciences 79:7, pages 557-567.
Crossref
Terry V. Zenser & Bernard B. Davis. 1990. Toxic Interactions. Toxic Interactions 61 86 .
Tammy M. Bray & James B. Kirkland. (1990) The metabolic basis of 3-methylindole-induced pneumotoxicity. Pharmacology & Therapeutics 46:1, pages 105-118.
Crossref
Hildegrand M. Schulle, Miriam Falzon & James B. McMahon. (1990) Metabolic activation and biological effects of nitrosamines in the mammalian lung. Pharmacology & Therapeutics 46:1, pages 95-103.
Crossref
Alex Sevanian & Hazel Peterson. (1989) Induction of cytotoxicity and mutagenesis is facilitated by fatty acid hydroperoxidase activity in Chinese hamster lung fibroblasts (V79 cells). Mutation Research/Genetic Toxicology 224:2, pages 185-196.
Crossref
M J SchlosserR D ShurinaG F Kalf. (1989) Metabolism of phenol and hydroquinone to reactive products by macrophage peroxidase or purified prostaglandin H synthase.. Environmental Health Perspectives 82, pages 229-237.
Crossref
J Schreiber, G L Foureman, M F Hughes, R P Mason & T E Eling. (1989) Detection of glutathione thiyl free radical catalyzed by prostaglandin H synthase present in keratinocytes. Journal of Biological Chemistry 264:14, pages 7936-7943.
Crossref
D C Thompson, Y N Cha & M A Trush. (1989) The peroxidase-dependent activation of butylated hydroxyanisole and butylated hydroxytoluene (BHT) to reactive intermediates. Journal of Biological Chemistry 264:7, pages 3957-3965.
Crossref
Carolyn Mottley & Ronald P. Mason. 1989. Spin Labeling. Spin Labeling 489 546 .
Paul Hochstein & Ahmed S. Atallah. (1988) The nature of oxidants and antioxidant systems in the inhibition of mutation and cancer. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 202:2, pages 363-375.
Crossref
Peter J. Formosa & Tammy M. Bray. (1988) Evidence for metabolism of 3-methylindole by prostaglandin H synthase and mixed-function oxidases in goat lung and liver microsomes. Biochemical Pharmacology 37:22, pages 4359-4366.
Crossref
James P. Kehrer, Brooke T. Mossman, Alex Sevanian, Michael A. Trush & Martyn T. Smith. (1988) Free radical mechanisms in chemical pathogenesis. Toxicology and Applied Pharmacology 95:3, pages 349-362.
Crossref
PETER J. O'BRIEN. (1988) Free-Radical-Mediated Chemical Carcinogenesis. Annals of the New York Academy of Sciences 534:1 Living in a C, pages 552-564.
Crossref
Hildegard M. Schuller. (1988) Small cell cancer of the lung. Biochemical Pharmacology 37:9, pages 1645-1649.
Crossref
Peter J. Harvison, Robert W. Egan, Paul H. Gale, Gary D. Christian, Brian S. Hill & Sidney D. Nelson. (1988) Acetaminophen and analogs as cosubstrates and inhibitors of prostaglandin H synthase. Chemico-Biological Interactions 64:3, pages 251-266.
Crossref
T W Petry & T E Eling. (1987) The mechanism for the inhibition of prostaglandin H synthase-catalyzed xenobiotic oxidation by methimazole. Reaction with free radical oxidation products.. Journal of Biological Chemistry 262:29, pages 14112-14118.
Crossref
Michael M. Iba. (1987) Comparative activation of 3,3′-dichlorobenzidine and related benzidines to mutagens in the Salmonella typhimurium assay by hepatic S9 and microsomes from rats pretreated with different inducers of cytochrome P-450. Mutation Research/Environmental Mutagenesis and Related Subjects 182:5, pages 231-241.
Crossref
B G Taffe, N Takahashi, T W Kensler & R P Mason. (1987) Generation of free radicals from organic hydroperoxide tumor promoters in isolated mouse keratinocytes. Formation of alkyl and alkoxyl radicals from tert-butyl hydroperoxide and cumene hydroperoxide.. Journal of Biological Chemistry 262:25, pages 12143-12149.
Crossref
Beat Lang & Michael M. Iba. (1987) Peroxidative activation of 3,3′-dichlorobenzidine to mutagenic products in the Salmonella typhimurium test. Mutation Research Letters 191:3-4, pages 139-143.
Crossref
Gisela H. Degen, Peter H. Jellinck & Richard J. Hershcopf. (1987) Prostaglandin H synthase catalyzes regiospecific release of tritium from labeled estradiol. Steroids 49:6, pages 561-580.
Crossref
P. Devanesan, E. Rogan & E. Cavalieri. (1987) The relationship between ionization potential and prostaglandin H synthase-catalyzed binding of aromatic hydrocarbons to DNA. Chemico-Biological Interactions 61:1, pages 89-95.
Crossref
Michael I. Luster, Lily H. Hong, Anne N. Tucker, Oscar Pung & Gary A. Boorman. 1986. Immunotoxicology. Immunotoxicology 279 292 .
B. Niggli, U. Friedrich, D. Hann & F.E. Würgler. (1986) Endogenous promutagen activation in the yeast Saccharomyces cerevisiae: factors influencing aflatoxin B1 mutagenicity. Mutation Research Letters 175:4, pages 223-229.
Crossref
Beat Lang, Karl Frei & Peter Maier. (1986) Prostaglandin synthase dependent aldrin epoxidation in hepatic and extrahepatic tissues of rats. Biochemical Pharmacology 35:20, pages 3643-3645.
Crossref
B. Lang & P. Maier. (1986) Lipid peroxidation dependent aldrin epoxidation in liver microsomes, hepatocytes and granulation tissue cells. Biochemical and Biophysical Research Communications 138:1, pages 24-32.
Crossref
Catharina Bäärnhielm & Göran Hansson. (1986) Oxidation of 1,4-dihydropyridines by prostaglandin synthase and the peroxidic function of cytochrome P-450. Biochemical Pharmacology 35:9, pages 1419-1425.
Crossref
T E Eling, J F Curtis, L S Harman & R P Mason. (1986) Oxidation of glutathione to its thiyl free radical metabolite by prostaglandin H synthase. A potential endogenous substrate for the hydroperoxidase.. Journal of Biological Chemistry 261:11, pages 5023-5028.
Crossref
L S Harman, D K Carver, J Schreiber & R P Mason. (1986) One- and two-electron oxidation of reduced glutathione by peroxidases.. Journal of Biological Chemistry 261:4, pages 1642-1648.
Crossref
Alan R. Buckpitt, Linda S. Bahnson & Ronald B. Franklin. (1986) Comparison of the arachidonic acid and NADPH-dependent microsomal metabolism of naphthalene and 2-methylnaphthalene and the effect of indomethacin on the bronchiolar necrosis. Biochemical Pharmacology 35:4, pages 645-650.
Crossref
J.P.N. Rosazza & M.W. Duffel. 1986. 323 405 .
G. Gordon Gibson & Paul SkettG. Gordon Gibson & Paul Skett. 1986. Introduction to Drug Metabolism. Introduction to Drug Metabolism 175 198 .
E Cavalieri & E Rogan. (1985) Role of radical cations in aromatic hydrocarbon carcinogenesis.. Environmental Health Perspectives 64, pages 69-84.
Crossref
J A Boyd & T E Eling. (1985) Metabolism of aromatic amines by prostaglandin H synthase.. Environmental Health Perspectives 64, pages 45-51.
Crossref
P J O'Brien. (1985) Free-radical-mediated DNA binding.. Environmental Health Perspectives 64, pages 219-232.
Crossref
P D Josephy. (1985) Oxidative activation of benzidine and its derivatives by peroxidases.. Environmental Health Perspectives 64, pages 171-178.
Crossref
Jeff A. Boyd, Errol Zeiger & Thomas E. Eling. (1985) The prostaglandin H synthase-dependent activation of 2-aminofluorene to products mutagenic to S. typhimurium strains TA98 and TA98NR. Mutation Research Letters 143:3, pages 187-190.
Crossref
T E Eling, R P Mason & K Sivarajah. (1985) The formation of aminopyrine cation radical by the peroxidase activity of prostaglandin H synthase and subsequent reactions of the radical.. Journal of Biological Chemistry 260:3, pages 1601-1607.
Crossref
Peter Moldéus, Roger Larsson & David Ross. 1985. Arachidonic Acid Metabolism and Tumor Initiation. Arachidonic Acid Metabolism and Tumor Initiation 171 198 .
Terry V. Zenser & Bernard B. Davis. 1985. Biochemistry of Arachidonic Acid Metabolism. Biochemistry of Arachidonic Acid Metabolism 127 149 .
J A Boyd & T E Eling. (1984) Evidence for a one-electron mechanism of 2-aminofluorene oxidation by prostaglandin H synthase and horseradish peroxidase.. Journal of Biological Chemistry 259:22, pages 13885-13896.
Crossref
Robert S. Krauss & Thomas E. Eling. (1984) Arachidonic acid-dependent cooxidation. Biochemical Pharmacology 33:21, pages 3319-3324.
Crossref
Peter Maier. 1984. Chemical Mutagens. Chemical Mutagens 233 260 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.