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Drug Metabolism Reviews Volume 14, 1983 - Issue 6
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Research Article

Bioactivation of Prodrugs: Structure-Pharmacokinetic Correlations of Benzodiazepine Esters

Gábor Maksay Central Research Institute for Chemistry Hungarian Academy of Sciences H-1525 Budapest, Pf. 17, Pusztaszeri UT, 59, Hungary
&
László Ötvös Central Research Institute for Chemistry Hungarian Academy of Sciences H-1525 Budapest, Pf. 17, Pusztaszeri UT, 59, Hungary
Pages 1165-1192 | Published online: 22 Sep 2008

Citations (8)

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Franz-Josef Leinweber. (1987) Possible Physiological Roles of Carboxylic Ester Hydrolases. Drug Metabolism Reviews 18:4, pages 379-439.
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Articles from other publishers (7)

Peter Buchwald & Nicholas Bodor. (1999) Quantitative Structure−Metabolism Relationships:  Steric and Nonsteric Effects in the Enzymatic Hydrolysis of Noncongener Carboxylic Esters. Journal of Medicinal Chemistry 42:25, pages 5160-5168.
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Shen K. Yang, Amy Huang & Jin‐Ding Huang. (2004) Enantioselectivity of esterases in human brain. Chirality 5:7, pages 565-568.
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Shen K. Yang, Kan Liu & F. Peter Guengerich. (2004) Enantioselective hydrolysis of oxazepam 3‐acetate by esterases in human and rat liver microsomes and rat brain s9 fraction. Chirality 2:3, pages 150-155.
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Shen K. Yang & Xiang-Lin Lu. (1989) Racemization Kinetics of Enantiomeric Oxazepams and Stereoselective Hydrolysis of Enantiomeric Oxazepam 3-Acetates in Rat Liver Microsomes and Brain Homogenate. Journal of Pharmaceutical Sciences 78:10, pages 789-795.
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Gábor Maksay & Miklós Simonyi. (1988) Nonequilibrium modulation of 35S-TBPS binding by benzodiazepine agonists and antagonists. Biochemical Pharmacology 37:11, pages 2195-2200.
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Nicholas Bodor & James J. Kaminski. 1987. 303 313 .
William M. Pardridge. 1985. 305 313 .

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