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Drug Metabolism Reviews Volume 14, 1983 - Issue 6
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Research Article

Methylthlolated Metabolites

Mitsuru Tateishi Department of Biochemistry, Nippon Roche Research Center 200 Kajiwara Kamakura, Japan
Pages 1207-1234 | Published online: 22 Sep 2008

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Lora E. Rikans. (1989) Influence of Aging on Chemically Induced Hepato-Toxicity: Role of Age-Related Changes in Metabolism. Drug Metabolism Reviews 20:1, pages 87-110.
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Wolfgang Dekant, Spyridon Vamvakas & M. W. Anders. (1989) Bioactivation of Nephrotoxic Haloalkenes by Glutathione Conjugation: Formation of Toxic and Mutagenic Intermediates by Cysteine Conjugate β-Lyase. Drug Metabolism Reviews 20:1, pages 43-83.
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Hiroki Tomisawa, Noriko Ichimoto, Shigeyasu Ichihara, Hideo Fukazawa & Mitsuru Tateishi. (1988) Involvement of Cystathionase in the Formation of Alkane-Thiols from Corresponding Cysteine Conjugates. Xenobiotica 18:9, pages 1029-1037.
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Hiroki Tomisawa, Noriko Ichimoto, Yohko Takanohashi, Shigeyasu Ichihara, Hideo Fukazawa & Mitsuru Tateishi. (1988) Purification and Characterization of Cysteine Conjugate Transaminases from Rat Liver. Xenobiotica 18:9, pages 1015-1028.
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A. Warrander, J. M. Allen & R. S. Andrews. (1985) Incorporation of radiolabelled amino acids into the sulphur-containing metabolites of paracetamol by the hamster. Xenobiotica 15:11, pages 891-897.
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H. Schwartz, I. Chu, D. C. Villeneuve, A. Viau & F. M. Benoit. (1985) Metabolites of 1,2,3,4‐tetrachlorobenzene in monkey urine. Journal of Toxicology and Environmental Health 15:5, pages 603-607.
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Articles from other publishers (27)

Ewan D. Booth, Joanne D. Kilgour & William P. Watson. (2004) Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-14C]-butadiene. Chemico-Biological Interactions 147:2, pages 213-232.
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G. Morel, M. Ban, D. Hettich & N. Huguet. (1999) Role of SAM-dependent thiol methylation in the renal toxicity of several solvents in mice. Journal of Applied Toxicology 19:1, pages 47-54.
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Kevan A. RichardsonMelanie M. C. G. PetersRené H. J. J. J. MegensPaul A. van ElburgBernard T. GoldingPeter J. BoogaardWilliam P. WatsonNico J. van Sittert. (1998) Identification of Novel Metabolites of Butadiene Monoepoxide in Rats and Mice. Chemical Research in Toxicology 11:12, pages 1543-1555.
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N. Plant, I. Kitchen, P. S. Goldfarb & G. G. Gibson. (1997) Developmental modulation of cysteine conjugate β-lyase/glutamine transaminase K/kynurenine aminotransferase mRNA in rat brain. European Journal of Drug Metabolism and Pharmacokinetics 22:4, pages 335-339.
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Yoshihisa Kato & Ryohei Kimura. (1997) Role of 3,4-Dichlorophenyl Methyl Sulfone, a Metabolite ofo-Dichlorobenzene, in the Changes in Hepatic Microsomal Drug-Metabolizing Enzymes Caused byo-Dichlorobenzene Administration in Rats. Toxicology and Applied Pharmacology 145:2, pages 277-284.
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Anne Hillenweck, Jean-Pierre Cravedi, Laurent Debrauwer, James C. KilleenJr.Jr., Myron BlissJr.Jr. & Denis E. Corpet. (1997) Chlorothalonil Biotransformation by Gastrointestinal Microflora:In VitroComparative Approach in Rat, Dog, and Human. Pesticide Biochemistry and Physiology 58:1, pages 34-48.
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B. Cossec, L. Cavelier, N. Moitessier-Bergé, G. Morel & J. de Ceaurriz. (1996) Formation of GSH-derivatives as a pathway for inactive intermediates in vinylidene chloride-treated rats. Toxicology Letters 89:3, pages 223-229.
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Peter Goldfarb. (2016) Doppelganger. Human & Experimental Toxicology 14:11, pages 932-933.
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K KataokaT KinouchiS AkimotoY Ohnishi. (1995) Bioactivation of cysteine conjugates of 1-nitropyrene oxides by cysteine conjugate beta-lyase purified from Peptostreptococcus magnus. Applied and Environmental Microbiology 61:11, pages 3781-3787.
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. (1995) Molecular cloning and expression of a cDNA for human kidney cysteine conjugate β -lyase . FEBS Letters 360:3, pages 277-280.
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Tomisawa Hiroki, Hayashi Masako, Uda Fumiaki, Okamoto Akira, Hattori Kenji, Ozawa Naoki & Tateishi Mitsuru. (1992) Purification and characterization of 3-mercaptolactic acid S-conjugate oxidases. Biochemical Pharmacology 44:4, pages 703-714.
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Michael Koob & Wolfgang Dekant. (1991) Bioactivation of xenobiotics by formation of toxic glutathione conjugates. Chemico-Biological Interactions 77:2, pages 107-136.
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Hiroki Tomisawa, Akira Okamoto, Kenji Hattori, Naoki Ozawa, Fumiaki Uda & Mitsuru Tateishi. (1990) Purification and characterization of 3-mercaptopyruvic acid S-conjugate reductases. Biochemical Pharmacology 40:9, pages 2047-2057.
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A. Parkinson, P.E. Thomas, D.E. Ryan, W. Levin, T. Fujita & S. Safe. (1988) Induction of rat liver microsomal cytochrome P-450 isozymes and epoxide hydrolase by a series of 4′-substituted-2,3,4,5-tetrachlorobiphenyls. Toxicology 53:2-3, pages 289-300.
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J.N.M. Commandeur, J.P.G. Brakenhoff, F.J.J. de Kanter & N.P.E. Vermeulen. (1988) Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Biochemical Pharmacology 37:23, pages 4495-4504.
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N M Mozier, K P McConnell & J L Hoffman. (1988) S-adenosyl-L-methionine:thioether S-methyltransferase, a new enzyme in sulfur and selenium metabolism.. Journal of Biological Chemistry 263:10, pages 4527-4531.
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M. Mikov, J. Caldwell, C.T. Dolphin & R.L. Smith. (1988) The role of intestinal microflora in the formation of the methylthio adduct metabolites of paracetamol. Biochemical Pharmacology 37:8, pages 1445-1449.
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C.T. Dolphin, J. Caldwell & R.L. Smith. (1987) Effect of poly rI:rC treatment upon the metabolism of [14C]-paracetamol in the BALB/cJ mouse. Biochemical Pharmacology 36:22, pages 3835-3840.
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Spyridon Vamvakas, Wolfgang Dekant, Klemens Berthold, Sabine Schmidt, Dieter Wild & Dietrich Henshler. (1987) Enzymatic transformation of mercapturic acids derived from halogenated alkenes to reactive and mutagenic intermediates. Biochemical Pharmacology 36:17, pages 2741-2748.
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Hideo Fukazawa, Hiroki Tomisawa, Shigeyasu Ichihara & Mitsuru Tateishi. (1987) Purification and properties of methyl sulfoxide reductases from rat kidney. Archives of Biochemistry and Biophysics 256:2, pages 480-489.
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E.C. Horning, K. Lertratanangkoon & M.G. Horning. (1987) Metabolism of bromobenzene. Journal of Chromatography A 399, pages 321-339.
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Wolfgang Dekant, Spyridon Vamvakas, Klemens Berthold, Sabine Schmidt, Dieter Wild & Dietrich Henschler. (1986) Bacterial β-lyase mediated cleavage and mutagenicity of cysteine conjugates derived from the nephrocarcinogenic alkenes trichloroethylene, tetrachloroethylene and hexachlorobutadiene. Chemico-Biological Interactions 60:1, pages 31-45.
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Hiroki Tomisawa, Hideo Fukazawa, Shigeyasu Ichihara & Mitsuru Tateishi. (1986) A novel pathway for formation of thiol-containing metabolites from cysteine conjugates. Biochemical Pharmacology 35:13, pages 2270-2272.
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Dieter Reichert & Sabine Schg?tz. (1986) Mercapturic acid formation is an activation and intermediary step in the metabolism of hexachlorobutadiene. Biochemical Pharmacology 35:8, pages 1271-1275.
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J.L. Maggs, N.R. Kitteringham, P.S. Grabowski & B.K. Park. (1986) Drug-protein conjugates—X. Biochemical Pharmacology 35:3, pages 505-513.
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Dieter Reichert, Sabine Schütz & Manfred Metzler. (1985) Excretion pattern and metabolism of hexachlorobutadiene in rats. Biochemical Pharmacology 34:4, pages 499-505.
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John R. Rice, Terry V. Zenser & Bernard B. Davis. 1985. Arachidonic Acid Metabolism and Tumor Initiation. Arachidonic Acid Metabolism and Tumor Initiation 125 169 .

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