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Drug Metabolism Reviews Volume 17, 1986 - Issue 1-2
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Research Article

Physical Methods in the Study of the Active Site Geometry of Cytochromes P-450

David F. V. Lewis Department of Biochemistry, University of Surrey Guildford, Surrey, GU2 5XH, England
Pages 1-66 | Published online: 22 Sep 2008

Citations (15)

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Read on this site (2)

David F. V. Lewis & John M. Pratt. (1998) The P450 Catalytic Cycle and Oxygenation Mechanism. Drug Metabolism Reviews 30:4, pages 739-786.
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Dennis V. Parke. (1997) A History of Drug Metabolism in the United Kingdom. Drug Metabolism Reviews 29:3, pages 801-851.
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Articles from other publishers (13)

Mary Grace I. Galinato, Tatyana Spolitak, David P. Ballou & Nicolai Lehnert. (2011) Elucidating the Role of the Proximal Cysteine Hydrogen-Bonding Network in Ferric Cytochrome P450cam and Corresponding Mutants Using Magnetic Circular Dichroism Spectroscopy. Biochemistry 50:6, pages 1053-1069.
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Bernard Testa & Stefanie D. Krämer. (2007) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 4:3, pages 257-405.
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Stewart B. Kirton, Carol A. Kemp, Nicholas P. Tomkinson, Steven St.‐Gallay & Michael J. Sutcliffe. (2002) Impact of incorporating the 2C5 crystal structure into comparative models of cytochrome P450 2D6. Proteins: Structure, Function, and Bioinformatics 49:2, pages 216-231.
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Stewart B Kirton, Carol A Baxter & Michael J Sutcliffe. (2002) Comparative modelling of cytochromes P450. Advanced Drug Delivery Reviews 54:3, pages 385-406.
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David Lewis. 2001. Guide to Cytochromes P450. Guide to Cytochromes P450 164 210 .
David F.V. Lewis & Peter Hlavica. (2000) Interactions between redox partners in various cytochrome P450 systems: functional and structural aspects. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1460:2-3, pages 353-374.
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Dennis A. Smith, Mark J. Ackland & Barry C. Jones. (1997) Properties of cytochrome P450 isoenzymes and their substrates part 2: properties of cytochrome P450 substrates. Drug Discovery Today 2:11, pages 479-486.
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Dennis A. Smith, Mark J. Ackland & Barry C. Jones. (1997) Properties of cytochrome P450 isoenzymes and their substrates Part 1: active site characteristics. Drug Discovery Today 2:10, pages 406-414.
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Vasily S. Oganesyan & Yuri A. Sharonov. (1997) A 4-term energy level scheme for the high-spin ferrous hemoproteins: Evidence for the 5En and 5B2 terms as the ground multiplets in hemoproteins with a histidine and a cysteine protein-derived heme ligand, respectively. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 53:3, pages 433-449.
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David F. V. Lewis. 1992. Reviews in Computational Chemistry. Reviews in Computational Chemistry 173 222 .
David F.V. Lewis, Costas Ioannides & Dennis V. Parke. (1989) Molecular orbital studies of oxygen activation and mechanisms of cytochromes P-450-mediated oxidative metabolism of xenobiotics. Chemico-Biological Interactions 70:3-4, pages 263-280.
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Janusz Z. Byczkowski & Teresa Gessner. (1988) Biological role of superoxide ion-radical. International Journal of Biochemistry 20:6, pages 569-580.
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David F.V. Lewis, Costas Ioannides & Dennis V. Parke. (1987) Structural requirements for substrates of cytochromes P-450 and P-448. Chemico-Biological Interactions 64:1-2, pages 39-60.
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