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Drug Metabolism Reviews Volume 19, 1988 - Issue 3-4
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Research Article

A Gompertz Age-Specific Mortality Rate Model of Aging, Hormesis, and Toxicity: Fixed-Dose Studies

Patricia J. Neafsey Department of Psychiatry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachusetts, 02111
,
Harold Boxenbaum Drug Metabolism Department, Merrell Dow Research Institute, 2110 E. Galbraith Road, Cincinnati, Ohio, 45215-6300
,
Domenic A. Ciraulo Department of Psychiatry, Tufts University School of Medicine and Veterans Administration Outpatient Clinic, 17 Court Street, Boston, Massachusetts, 02108
&
Donna J. Fournier Pharmacology and Toxicology Section, School of Pharmacy University of Connecticut, Storrs, Connecticut, 06268
Pages 369-401 | Published online: 22 Sep 2008

Citations (12)

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Read on this site (4)

Gary A. Thompson, Jacquelyn Smithers & Harold Boxenbaum. (1990) Biphasic Mortality Response of Chipmunks in the Wild to Single Doses of Ionizing Radiation: Toxicity and Longevity Hormesis. Drug Metabolism Reviews 22:2-3, pages 269-289.
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Patricia J. Neafsey. (1989) Age-Specific Mortality Rate Analysis: A New Paradigm for Risk Assessment. Drug Metabolism Reviews 21:3, pages 471-485.
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Patricia J. Neafsey, Harold Boxenbaum, Domenic A. Ciraulo & Donna J. Fournier. (1989) A Gompertz Age-Specific Mortaliu Rate Model of Aging: Modification by Dietary Restriction in Rats. Drug Metabolism Reviews 21:2, pages 351-365.
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Patricia J. Neafsey, Domenic A. Ciraulo, Harold Boxenbaum & Donna J. Fournier. (1989) A Gompertz Age-Specific Mortality Rate Model of Aging, Hormesis, and Toxicity: Dose-Response Studies. Drug Metabolism Reviews 20:1, pages 111-150.
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Articles from other publishers (8)

Víctor Casero-Alonso, Andrey Pepelyshev & Weng K. Wong. (2018) A web-based tool for designing experimental studies to detect hormesis and estimate the threshold dose. Statistical Papers 59:4, pages 1307-1324.
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Eva Terzibasi, Christel Lefrançois, Paolo Domenici, Nils Hartmann, Michael Graf & Alessandro Cellerino. (2009) Effects of dietary restriction on mortality and age-related phenotypes in the short-lived fish Nothobranchius furzeri . Aging Cell 8:2, pages 88-99.
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Ganna V. Semenchenko, Anatoli I. Yashin, Thomas E. Johnson & James W. Cypser. 2007. Advances in Statistical Methods for the Health Sciences. Advances in Statistical Methods for the Health Sciences 179 194 .
P J Neafsey. (2016) Age-specific mortality rate analyses suggest response from caloric restriction and hormesis are due to separate mechanisms. Human & Experimental Toxicology 19:6, pages 342-344.
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P.J. Neafsey, W.B. Lowrie & F.T. Cross. (1995) A mortality kinetics approach to characterizing the fractionated wxposure-mortality response relationship of radon progeny. Mechanisms of Ageing and Development 83:2, pages 65-85.
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Charles V. Mobbs. (1994) Molecular hysteresis: Residual effects of hormones and glucose on genes during aging. Neurobiology of Aging 15:4, pages 523-534.
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Harold Boxenbaum. (1991) Gompertz mortality analysis: aging, longevity hormesis and toxicity. Archives of Gerontology and Geriatrics 13:2, pages 125-137.
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Patricia J. Neafsey. (1990) Longevity Hormesis. A review. Mechanisms of Ageing and Development 51:1, pages 1-31.
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