18
Views
42
CrossRef citations to date
0
Altmetric
Research Article

Radiation Protectors: the Unexpected Benefits

&
Pages 13-42 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

K. N. Manola, G. I. Terzoudi, C. E. Dardoufas, S. I. Malik & G. E. Pantelias. (2003) Radioprotective effect of amifostine on cells from cancer prone patients and healthy individuals studied by the G2 and PCC assays. International Journal of Radiation Biology 79:10, pages 831-838.
Read now
Y. Kataoka, J. S. Murley, R. Patel, D. J. Grdina. (2000) Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines. International Journal of Radiation Biology 76:5, pages 633-639.
Read now
MariaD. Bacolod, Arturo Lopez-Anaya, Burde Kamath & Vimal Kishore. (1996) Studies of the Stability of a Substituted Phosphorothioate Using an Improved High Performance Liquid Chromatography Assay Coupled with Electrochemical Detection. Journal of Liquid Chromatography & Related Technologies 19:8, pages 1277-1289.
Read now
V. Dragojević-Simić, M. Čolić & S. Gašić. (1994) Influence of a Radioprotector WR-638 on the Lymphoid Compartment of the Irradiated Rat Thymus: A Flow Cytometric Analysis. International Journal of Radiation Biology 66:2, pages 143-150.
Read now
E.K. Balcer-Kubiczek, G.H. Harrison, C.K. Hill & W.F. Blakely. (1993) Effects of WR-1065 and WR-151326 on Survival and Neoplastic Transformation in C3H/10T½ Cells Exposed to TRIGA or JANUS Fission Neutrons. International Journal of Radiation Biology 63:1, pages 37-46.
Read now
. (1992) Abstracts. Cancer Investigation 10:sup1, pages 1-41.
Read now
W. McCulloch, B. J. Scheffler & P. S. Schein. (1991) New Protective Agents for Bone Marrow in Cancer Therapy. Cancer Investigation 9:3, pages 279-287.
Read now

Articles from other publishers (34)

Jelena Popović, Andrijana Klajn, Tatjana Paunesku, Qing Ma, Si Chen, Barry Lai, Milena Stevanović & Gayle E. Woloschak. (2019) Neuroprotective Role of Selected Antioxidant Agents in Preventing Cisplatin-Induced Damage of Human Neurons In Vitro. Cellular and Molecular Neurobiology 39:5, pages 619-636.
Crossref
Gopakumar Gopinathan Nair & Cherupally Krishnan Krishnan Nair. (2013) Radioprotective Effects of Gallic Acid in Mice. BioMed Research International 2013, pages 1-13.
Crossref
Carsten Berndt, Tino Kurz, Markus Selenius, Aristi P. Fernandes, Margareta R. Edgren & Ulf T. Brunk. (2010) Chelation of lysosomal iron protects against ionizing radiation. Biochemical Journal 432:2, pages 295-301.
Crossref
Goran Gajski & Vera Garaj-Vrhovac. (2009) Radioprotective Effects of Honeybee Venom ( Apis mellifera ) Against 915-MHz Microwave Radiation–Induced DNA Damage in Wistar Rat Lymphocytes: In Vitro Study . International Journal of Toxicology 28:2, pages 88-98.
Crossref
M. Fevzi Ozkaynak, Indira Sahdev, Thomas G. Gross, John E. Levine, Alexandra C. Cheerva, Michael K. Richards, Marta K. Rozans, Peter J. Shaw & Richard P. Kadota. (2008) A Pilot Study of Addition of Amifostine to Melphalan, Carboplatin, Etoposide, and Cyclophosphamide With Autologous Hematopoietic Stem Cell Transplantation in Pediatric Solid Tumors–A Pediatric Blood and Marrow Transplant Consortium Study. Journal of Pediatric Hematology/Oncology 30:3, pages 204-209.
Crossref
Uma Pathak, Lokesh Kumar Pandey, Avik Mazumder, Rajesh Kumar & S.K. Raza. (2008) A SIMPLE AND EFFICIENT MICROWAVE MEDIATED SYNTHESIS OF NOVEL S- HETEROCYCLIC AMINOALKYLAMINO ETHNANE THIOLS. Heterocyclic Communications 14:4.
Crossref
Vesna Benković, Nada Orsolić, Anica Horvat Knežević, Snježana Ramić, Domagoj Ðikić, Ivan Bašić & Nevenka Kopjar. (2008) Evaluation of the Radioprotective Effects of Propolis and Flavonoids in Gamma-Irradiated Mice: The Alkaline Comet Assay Study. Biological and Pharmaceutical Bulletin 31:1, pages 167-172.
Crossref
Yasushi Kataoka, Jeffrey S. Murley, Kenneth L. Baker & David J. Grdina. (2007) Relationship between Phosphorylated Histone H2AX Formation and Cell Survival in Human Microvascular Endothelial Cells (HMEC) as a Function of Ionizing Radiation Exposure in the Presence or Absence of Thiol-Containing Drugs. Radiation Research 168:1, pages 106-114.
Crossref
Vanna M. Dest. (2006) Radioprotectants: Adding Quality of Life to Survivorship?. Seminars in Oncology Nursing 22:4, pages 249-256.
Crossref
Michael I. Koukourakis & Vassilios Danielidis. (2005) Preventing radiation induced xerostomia. Cancer Treatment Reviews 31:7, pages 546-554.
Crossref
A Spencer, N Horvath, J Gibson, H M Prince, R Herrmann, J Bashford, D Joske, A Grigg, J McKendrick, I Prosser, R Lowenthal, S Deveridge & K Taylor. (2005) Prospective randomised trial of amifostine cytoprotection in myeloma patients undergoing high-dose melphalan conditioned autologous stem cell transplantation. Bone Marrow Transplantation 35:10, pages 971-977.
Crossref
Michael I. Koukourakis, Alexandra Giatromanolaki, Wen Chong, Costantinos Simopoulos, Alexandros Polychronidis, Efthimios Sivridis & Adrian L. Harris. (2004) Amifostine induces anaerobic metabolism and hypoxia-inducible factor 1α. Cancer Chemotherapy and Pharmacology 53:1, pages 8-14.
Crossref
Joseph A. Spadaro, Mark T. Baesl, Amanda C. Conta, Bryan M. Margulies & Timothy A. Damron. (2003) Effects of Irradiation on the Appositional and Longitudinal Growth of the Tibia and Fibula of the Rat With and Without Radioprotectant. Journal of Pediatric Orthopaedics 23:1, pages 35-40.
Crossref
Joseph Spadaro, Mark Baesl, Amanda Conta, Bryan Margulies & Timothy Damron. (2003) Journal of Pediatric Orthopedics 23:1, pages 35-40.
Crossref
Jean Bourhis & Dominique Rosine. (2002) Radioprotective effect of amifostine in patients with head and neck squamous cell carcinoma. Seminars in Oncology 29:6, pages 61-62.
Crossref
David J. Grdina, Yasushi Kataoka, Jeffrey S. Murley, Kirsten Swedberg, John Y. Lee, Nancy Hunter, Ralph R. Weichselbaum & Luka Milas. (2002) Antimetastatic effectiveness of amifostine therapy following surgical removal of Sa-NH tumors in mice. Seminars in Oncology 29:6, pages 22-28.
Crossref
MI Koukourakis. (2002) Amifostine in clinical oncology: current use and future applications. Anti-Cancer Drugs 13:3, pages 181-209.
Crossref
Matthew M. Poggi, C.Norman Coleman & James B. Mitchell. (2001) Sensitizers and protectors of radiation and chemotherapy. Current Problems in Cancer 25:6, pages 334-411.
Crossref
Marie-Louise H. Fj�llskog, Dan. P. K. Granberg, Staffan L. V. Welin, Christopher Eriksson, Kjell E. �berg, Eva T. Janson & Barbro K. Eriksson. (2001) Treatment with cisplatin and etoposide in patients with neuroendocrine tumors. Cancer 92:5, pages 1101-1107.
Crossref
Timothy A. Damron, Joseph A. Spadaro, Robert M. Tamurian & Leatha A. Damron. (2000) Sparing of radiation-induced damage to the physis: fractionation alone compared to amifostine pretreatment. International Journal of Radiation Oncology*Biology*Physics 47:4, pages 1067-1071.
Crossref
J Bourhis, R De Crevoisier, B Abdulkarim, E Deutsch, A Lusinchi, B Luboinski, P Wibault & F Eschwege. (2000) A randomized study of very accelerated radiotherapy with and without amifostine in head and neck squamous cell carcinoma. International Journal of Radiation Oncology*Biology*Physics 46:5, pages 1105-1108.
Crossref
R. M. Tamurian, T. A. Damron & J. A. Spadaro. (2005) Sparing radiation‐induced damage to the physis by radioprotectant drugs: Laboratory analysis in a rat model. Journal of Orthopaedic Research 17:2, pages 286-292.
Crossref
M. Pospíšil. 1999. Fundamentals for the Assessment of Risks from Environmental Radiation. Fundamentals for the Assessment of Risks from Environmental Radiation 411 420 .
E Raymond. (1996) Les médicaments chimioprotecteurs. Mécanismes d'action et applications cliniques. La Revue de Médecine Interne 17:11, pages 936-944.
Crossref
R.L. Capizzi. (1996) The preclinical basis for broad-spectrum selective cytoprotection of normal tissues from cytotoxic therapies by amifostine (Ethyol®). European Journal of Cancer 32, pages S5-S16.
Crossref
G.J. Peters & W.J.F. van der Vijgh. (1995) Protection of Normal Tissues from the Cytotoxic Effects of Chemotherapy and Radiation by Amifostine (WR-2721): Preclinical Aspects. European Journal of Cancer 31, pages S1-S7.
Crossref
J Oiry, JY Pue, JD Laval, M Fatome & JL Imbach. (1995) Synthesis and radioprotective activity of WR-1065 derivatives: N-(2-acetylthioethyl)-1,3-propanediamine and N,N′-bis(2-acetylthioethyl)-1,3-propanediamine. European Journal of Medicinal Chemistry 30:1, pages 47-52.
Crossref
Yulu Mao, Gert Lubec, Nikola Getoff, Sonja Solar & Ruth M. Quint. (1994) The effect of homocysteine thiolactone and its α-alkylated derivative on the survival of irradiated E. coli AB1157. Radiation Physics and Chemistry 44:5, pages 473-478.
Crossref
Robert L Capizzi, Barbara J. Scheffler & Philip S. Schein. (1993) Amifostine-mediated protection of normal bone marrow from cytotoxic chemotherapy. Cancer 72:S11, pages 3495-3501.
Crossref
John H. McDonough, Paul C. Mele & Carol G. Franz. (1992) Comparison of behavioral and radioprotective effects of WR-2721 and WR-3689. Pharmacology Biochemistry and Behavior 42:2, pages 233-243.
Crossref
M.L Patchen, T.J MacVittie & L.M Souza. (1992) Postirradiation treatment with granulocyte colony-stimulating factor and preirradiation WR-2721 administration synergize to enhance hemopoietic reconstitution and increase survival. International Journal of Radiation Oncology*Biology*Physics 22:4, pages 773-779.
Crossref
M. L. Patchen, T. J. MacVittie & L. M. Souza. 1992. Combination Therapies. Combination Therapies 215 222 .
Ju. I. Gubskiy, E. L. Levitsky, R. G. Primak & A. N. Velichko. (1991) Change in the structural condition of the fractionated liver chromatin under lipid peroxidation activation. Biopolymers and Cell 7:3, pages 89-94.
Crossref
William McCulloch, Barbara Scheffler & Philip Schein. 1991. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 509 516 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.