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Drug Metabolism Reviews Volume 20, 1989 - Issue 1
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Research Article

A Gompertz Age-Specific Mortality Rate Model of Aging, Hormesis, and Toxicity: Dose-Response Studies

Patricia J. Neafsey Department of Psychiatry, Tufts University School of Medicine, 136 Harrison Avenue, Boston, Massachuetts, 02111
,
Domenic A. Ciraulo Department of Psychiatry, Tufts University School of Medicine and Veterans Administration Outpatient Clinic, 17 Court Street, Boston, Massachusetts, 02108
,
Harold Boxenbaum Drug Metabolism Department, Merrell Dow Research Institute, 2110 East Galbraith Road, Cincinnati, Ohio, 45215-6300
&
Donna J. Fournier Pharmacology and Toxicology Section, School of Pharmacy University of Connecticut, Storrs, Connecticut, 06268
Pages 111-150 | Published online: 22 Sep 2008

Citations (10)

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Read on this site (5)

KennethT. Bogen. (1997) Do U.S. county data disprove linear no‐threshold predictions of lung cancer risk for residential radon?‐A preliminary assessment of biological plausibility. Human and Ecological Risk Assessment: An International Journal 3:2, pages 157-186.
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Gary A. Thompson, Jacquelyn Smithers & Harold Boxenbaum. (1990) Biphasic Mortality Response of Chipmunks in the Wild to Single Doses of Ionizing Radiation: Toxicity and Longevity Hormesis. Drug Metabolism Reviews 22:2-3, pages 269-289.
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Patricia J. Neafsey. (1989) Age-Specific Mortality Rate Analysis: A New Paradigm for Risk Assessment. Drug Metabolism Reviews 21:3, pages 471-485.
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Patricia J. Neafsey, Harold Boxenbaum, Domenic A. Ciraulo & Donna J. Fournier. (1989) A Gompertz Age-Specific Mortaliu Rate Model of Aging: Modification by Dietary Restriction in Rats. Drug Metabolism Reviews 21:2, pages 351-365.
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Patricia J. Neafsey, Harold Boxenbaum, Domenic A. Ciraulo & Donna J. Fournier. (1988) A Gompertz Age-Specific Mortality Rate Model of Aging, Hormesis, and Toxicity: Fixed-Dose Studies. Drug Metabolism Reviews 19:3-4, pages 369-401.
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Articles from other publishers (5)

P J Neafsey. (2016) Age-specific mortality rate analyses suggest response from caloric restriction and hormesis are due to separate mechanisms. Human & Experimental Toxicology 19:6, pages 342-344.
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Tarynn Matthew Witten & Tim Eakin. (1997) Multiphasic models of survival: Analysis of mortality rate change regions and the issue of finite species lifespan. Experimental Gerontology 32:3, pages 259-285.
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P.J. Neafsey, W.B. Lowrie & F.T. Cross. (1995) A mortality kinetics approach to characterizing the fractionated wxposure-mortality response relationship of radon progeny. Mechanisms of Ageing and Development 83:2, pages 65-85.
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Harold Boxenbaum. (1991) Gompertz mortality analysis: aging, longevity hormesis and toxicity. Archives of Gerontology and Geriatrics 13:2, pages 125-137.
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Patricia J. Neafsey. (1990) Longevity Hormesis. A review. Mechanisms of Ageing and Development 51:1, pages 1-31.
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