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Research Article

Assessing Human Health Risks from Exposure to Di(2-Ethylhexyl). Phthalate (DEHP) and Related Phthalates: Scientific Issues

Carl O. Schulz Department of Environmental Health Sciences, University of South Carolina, School of Public Health, Columbia, South Carolina, 29208
Pages 111-120 | Published online: 22 Sep 2008

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Wolfgang W. Huber, Bettina Grasl-kraupp & Rolf Schulte-hermann. (1996) Hepatocarcinogenic Potential of Di(2-Ethylhexyl)phthalate in Rodents and its Implications on Human Risk. Critical Reviews in Toxicology 26:4, pages 365-481.
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M.D. Smith, M.H. Grant, C.R. Blass, J.M. Courtney & J.C. Barbenel. (1996) Poly(vinyl chloride) formulations: Acute toxicity to cultured human cell lines. Journal of Biomaterials Science, Polymer Edition 7:5, pages 453-459.
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Articles from other publishers (20)

Yanhua Wu, Youbin Si, Dongmei Zhou & Juan Gao. (2015) Adsorption of diethyl phthalate ester to clay minerals. Chemosphere 119, pages 690-696.
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Xiaoxia Ye, Juan Ma, Yongjian Yang & Fang Jin. (2014) Analysis of 21 phthalate leachables in metered dose inhalers by gas chromatography tandem mass spectrometry. Anal. Methods 6:12, pages 4083-4089.
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Jaime Breilh. 2014. La Recherche Écosanté en pratique. La Recherche Écosanté en pratique 67 77 .
Jaime Breilh. 2012. Ecohealth Research in Practice. Ecohealth Research in Practice 59 68 .
Pei-Shan Liu, Fu-Wei Tseng & Jenn-Hwa Liu. (2009) Comparative suppression of phthalate monoesters and phthalate diesters on calcium signalling coupled to nicotinic acetylcholine receptors. The Journal of Toxicological Sciences 34:3, pages 255-263.
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Huan-Xin Weng, Yang-Ming Zhu, Ya-Chao Qin, Jian-Yu Chen & Xun-Hong Chen. (2008) Accumulation discrepancy of heavy metal and organic pollutants in three near-shore depositional environments, southeastern China. Journal of Asian Earth Sciences 31:4-6, pages 522-532.
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B. Bagó, Y. Martı́n, G. Mejı́a, F. Broto-Puig, J. Dı́az-Ferrero, M. Agut & L. Comellas. (2005) Di-(2-ethylhexyl)phthalate in sewage sludge and post-treated sludge: Quantitative determination by HRGC-MS and mass spectral characterization. Chemosphere 59:8, pages 1191-1195.
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Sung Chul Kim, Hye Jeong Yoon, Jang Won Lee, Jaewon Yu, Eun-Seok Park & Sang-Cheol Chi. (2005) Investigation of the release behavior of DEHP from infusion sets by paclitaxel-loaded polymeric micelles. International Journal of Pharmaceutics 293:1-2, pages 303-310.
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C. S. Quan, Q. Liu, W. J. Tian, J. Kikuchi & S. D. Fan. (2004) Biodegradation of an endocrine-disrupting chemical, di-2-ethylhexyl phthalate, by Bacillus subtilis No. 66. Applied Microbiology and Biotechnology 66:6, pages 702-710.
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Ivelisse Col�n & Jean-Marie D. Dimandja. (2004) High-throughput analysis of phthalate esters in human serum by direct immersion SPME followed by isotope dilution?fast GC/MS. Analytical and Bioanalytical Chemistry 380:2, pages 275-283.
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Lu Kaun-Yu, Tseng Fu-Wei, Wu Chia-Jung & Liu Pei-Shan. (2004) Suppression by phthalates of the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells. Toxicology 200:2-3, pages 113-121.
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Hariklia N. Gavala, Felipe Alatriste-Mondragon, Reza Iranpour & Birgitte K. Ahring. (2003) Biodegradation of phthalate esters during the mesophilic anaerobic digestion of sludge. Chemosphere 52:4, pages 673-682.
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Sandra S. Hill, Brenda R. Shaw & Alan H. B. Wu. (2003) Plasticizers, antioxidants, and other contaminants found in air delivered by PVC tubing used in respiratory therapy. Biomedical Chromatography 17:4, pages 250-262.
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Sandra S. Hill, Brenda R. Shaw & Alan H.B. Wu. (2001) The clinical effects of plasticizers, antioxidants, and other contaminants in medical polyvinylchloride tubing during respiratory and non-respiratory exposure. Clinica Chimica Acta 304:1-2, pages 1-8.
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Peter Lindequist Madsen, Jesper Bandsholm Thyme, Kaj Henriksen, Per Møldrup & Peter Roslev. (1999) Kinetics of Di-(2-ethylhexyl)phthalate Mineralization in Sludge-Amended Soil. Environmental Science & Technology 33:15, pages 2601-2606.
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GARY M. WILLIAMS & CARMEN PERRONE. (1996) Mechanism-based Risk Assessment of Peroxisome Proliferating Rodent Hepatocarcinogens. Annals of the New York Academy of Sciences 804:1 Peroxisomes, pages 554-572.
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H. A. A. M. Dirven, P. H. H. van den Broek, A. M. M. Arends, H. H. Nordkamp, A. J. G. M. de Lepper, P. Th. Henderson & F. J. Jongeneelen. (1993) Metabolites of the plasticizer di (2-ethylhexyl) phthalate in urine samples of workers in polyvinylchloride processing industries. International Archives of Occupational and Environmental Health 64:8, pages 549-554.
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B.B. Harsanyi, W.C. Foong, R.E. Howell, P. Hidi & D.W. Jones. (2016) Hamster Cheek-pouch Testing of Dental Soft Polymers. Journal of Dental Research 70:6, pages 991-996.
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David A. Pink, Wai‐Choong Foong, Derek W. Jones, Kimberly A. Gates, Micheal Mezei & Kevin Farrell. (2009) Plasticizer permeation across mucosal tissue: An experimental and theoretical study. Journal of Applied Biomaterials 2:1, pages 41-48.
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Dorothy C. Gosting, M. Ellin Doyle, Carol E. Steinhart & Barbara A. Cochrane. 1991. Food Safety 1990. Food Safety 1990 171 259 .

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