32
Views
23
CrossRef citations to date
0
Altmetric
Research Article

Human Placental Xenobiotic and Steroid Biotransformations Catalyzed By Cytochrome P450, Epoxide Hydrolase, and Glutathione S-Transferase Activities and Their Relationships to Maternal Cigarette Smoking

&
Pages 427-461 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Shakil Ahmed Saghir, Sarosh Ahmed Khan & Alene Theresa McCoy. (2012) Ontogeny of mammalian metabolizing enzymes in humans and animals used in toxicological studies. Critical Reviews in Toxicology 42:5, pages 323-357.
Read now
Jukka Hakkola, Olavi Pelkonen, Markku Pasanen & Hannu Raunio. (1998) Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity. Critical Reviews in Toxicology 28:1, pages 35-72.
Read now
Markku Pasanen & Olavi Pelkonen. (1994) The Expression and Environmental Regulation of P450 Enzymes in Human Placenta. Critical Reviews in Toxicology 24:3, pages 211-229.
Read now
Mont R. Juchau, Qwihee P. Lee & Alan G. Fantel. (1992) Xenobiotic Biotransfor Mation/Bioactivation in Organogenesis-Stage Conceptal Tissues: Implications for Embryotoxicity and Teratogenesis. Drug Metabolism Reviews 24:2, pages 195-238.
Read now

Articles from other publishers (19)

Olavi Pelkonen. (2015) Drug Metabolism - From In Vitro to In Vivo , From Simple to Complex . Basic & Clinical Pharmacology & Toxicology 117:3, pages 147-155.
Crossref
Elaine Christine Dantas Moises, Luciana de Barros Duarte, Ricardo de Carvalho Cavalli, Daniela Miarelli Carvalho, Gabriela Campos de Oliveira Filgueira, Maria Paula Marques, Vera Lucia Lanchote & Geraldo Duarte. (2015) Transplacental Distribution of Lidocaine and Its Metabolite in Peridural Anesthesia Administered to Patients With Gestational Diabetes Mellitus. Reproductive Sciences 22:7, pages 791-797.
Crossref
Elaine Christine Dantas Moisés, Luciana de Barros Duarte, Ricardo de Carvalho Cavalli, Vera Lúcia Lanchote, Geraldo Duarte & Sérgio Pereira da Cunha. (2005) Pharmacokinetics and transplacental distribution of fentanyl in epidural anesthesia for normal pregnant women. European Journal of Clinical Pharmacology 61:7, pages 517-522.
Crossref
M.P. Gallegos-Arreola, C.M. Batista-Gonz?lez, J.L. Delgado-Lamas, L.E. Figuera, A.M. Puebla-P?rez, L. Arnaud-L?pez, V. Peralta-Leal, L.J. Ram?rez-Jirano & G.M. Z??iga-Gonz?lez. (2004) Cytochrome P4501A1 polymorphism is associated with susceptibility to acute lymphoblastic leukemia in adult Mexican patients. Blood Cells, Molecules, and Diseases 33:3, pages 326-329.
Crossref
Ricardo de Carvalho Cavalli, Vera Lúcia Lanchote, Geraldo Duarte, Elaine Christine Moisés Dantas, Maria Fernanda Massoni de Prado, Luciana Barros de Duarte & Sérgio Pereira da Cunha. (2004) Pharmacokinetics and transplacental transfer of lidocaine and its metabolite for perineal analgesic assistance to pregnant women. European Journal of Clinical Pharmacology 60:8, pages 569-574.
Crossref
T.I. Ala-Kokko, P. Myllynen & K. Vähäkangas. (2000) Ex vivo perfusion of the human placental cotyledon: implications for anesthetic pharmacology. International Journal of Obstetric Anesthesia 9:1, pages 26-38.
Crossref
B. Yan, L. Matoney & D. Yang. (1999) Human Carboxylesterases in Term Placentae: Enzymatic Characterization, Molecular Cloning and Evidence for the Existence of Multiple Forms. Placenta 20:7, pages 599-607.
Crossref
Markku Pasanen. (1999) The expression and regulation of drug metabolism in human placenta. Advanced Drug Delivery Reviews 38:1, pages 81-97.
Crossref
Maja KrajinovicDamian LabudaChantal RicherSepideh KarimiDaniel Sinnett. (1999) Susceptibility to Childhood Acute Lymphoblastic Leukemia: Influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 Genetic Polymorphisms. Blood 93:5, pages 1496-1501.
Crossref
Maarten F.C.M Knapen, Petra L.M Zusterzeel, Wilbert H.M Peters & Eric A.P Steegers. (1999) Glutathione and glutathione-related enzymes in reproduction. European Journal of Obstetrics & Gynecology and Reproductive Biology 82:2, pages 171-184.
Crossref
Carolyn S. Bentivegna, Michael A. Ihnat, Nicole S. Baptiste & Joshua W. Hamilton. (1998) Developmental Regulation of the 3-Methylcholanthrene- and Dioxin-InducibleCYP1A5Gene in Chick Embryo Liverin Vivo. Toxicology and Applied Pharmacology 151:1, pages 166-173.
Crossref
Jukka Hakkola, Markku Pasanen, Janne Hukkanen, Olavi Pelkonen, Jukka Mäenpää, Robert J. Edwards, Alan R. Boobis & Hannu Raunio. (1996) Expression of xenobiotic-metabolizing cytochrome P450 Forms in human full-term placenta. Biochemical Pharmacology 51:4, pages 403-411.
Crossref
Tero I. Ala‐Kokko, Päivi Pienimäki, Riitta Herva, Arno I. Hollmén, Olavi Pelkonen & Kirsi Vähäkangas. (2009) Transfer of Lidocaine and Bupivacaine Across the Isolated Perfused Human Placenta *. Pharmacology & Toxicology 77:2, pages 142-148.
Crossref
Sergey V. Kotelevtsev, Victor V. Obrazsov, Cyril N. Novicov & Ludmila I. Stepanova. 1995. Molecular Aspects of Oxidative Drug Metabolizing Enzymes. Molecular Aspects of Oxidative Drug Metabolizing Enzymes 533 548 .
Mrinal K. Sanyal, You-Lan Li & Kathleen Belanger. (1994) Metabolism of polynuclear aromatic hydrocarbon in human term placenta influenced by cigarette smoke exposure. Reproductive Toxicology 8:5, pages 411-418.
Crossref
Pius Joseph, Shanthala N. Srinivasan, Janusz Z. Byczkowski & Arun P. Kulkarni. (1994) Bioactivation of benzo(a)pyrene-7,8-dihydrodiol catalyzed by lipoxygenase purified from human term placenta and conceptal tissues. Reproductive Toxicology 8:4, pages 307-313.
Crossref
Olavi Pelkonen. (2016) The Role of Toxicokinetics in Developmental Toxicity Testing: Lessons from Comparative Developmental Drug Metabolism. Drug Information Journal 28:1, pages 225-234.
Crossref
H Autrup. (1993) Transplacental transfer of genotoxins and transplacental carcinogenesis.. Environmental Health Perspectives 101:suppl 2, pages 33-38.
Crossref
Mrinal K. Sanyal, You-Lan Li, William J. Biggers, Jayavanthi Satish & Eytan R. Barnea. (1993) Augmentation of polynuclear aromatic hydrocarbon metabolism of human placental tissues of first-trimester pregnancy by cigarette smoke exposure. American Journal of Obstetrics and Gynecology 168:5, pages 1587-1597.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.