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Research Article

Radical Intermediates in the Cytochrome P-450-Catalyzed Oxidation of Aliphatic Hydrocarbons

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Pages 183-191 | Published online: 22 Sep 2008

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Alexandre Gagnon, Martin Duplessis & Lee Fader. (2010) Arylcyclopropanes: Properties, Synthesis and Use in Medicinal Chemistry. Organic Preparations and Procedures International 42:1, pages 1-69.
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R. T. STREEPER, P. G. PEARSON, Z. ZHAO, S. A. MIZSAK, P. E. SANDERS, L. C. WIENKERS & J. J. VRBANAC. (1997) In vitro metabolic transformations of 2,4- dipyrrolidinylp yrimidine : a chemical probe for P450-mediated oxidation of tirilazad mesylate. Xenobiotica 27:11, pages 1131-1145.
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F. P. Guengerich, O. Okazaki, Y. Seto & T. L. Macdonald. (1995) Radical cation intermediates in N-dealkylation reactions. Xenobiotica 25:7, pages 689-709.
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John Timbrell. 2008. Principles of Biochemical Toxicology, Fourth Edition. Principles of Biochemical Toxicology, Fourth Edition 75 127 .
Hassan Hazimeh, Frédéric Kanoufi, Catherine Combellas, Jean-Marc Mattalia, Caroline Marchi-Delapierre & Michel Chanon. (2008) Radical Clocks, Solvated Electrons, and Magnesium. Heterogeneous versus Homogeneous Electron Transfer. Selectivity at Interfaces. The Journal of Physical Chemistry C 112:7, pages 2545-2557.
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F. Korte, G. Kvesitadze, D. Ugrekhelidze, M. Gordeziani, G. Khatisashvili, O. Buadze, G. Zaalishvili & F. Coulston. (2000) Organic Toxicants and Plants. Ecotoxicology and Environmental Safety 47:1, pages 1-26.
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John D. Lipscomb, Sang-Kyu Lee, Jeremy C. Nesheim, Yi Jin, Bradley J. Wallar & Xiao-Yun Zhang. 1999. Iron Metabolism. Iron Metabolism 323 339 .
Stephane Mabie, Kay Castagnoli & Neal Castagnoli. 1999. Handbook of Drug Metabolism. Handbook of Drug Metabolism 49 79 .
F. Peter Guengerich, Chul-Ho Yun & Timothy L. Macdonald. (1996) Evidence for a 1-Electron Oxidation Mechanism in N-Dealkylation of N,N-Dialkylanilines by Cytochrome P450 2B1. Journal of Biological Chemistry 271:44, pages 27321-27329.
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Wolf-Dietrich Woggon. 1997. Bioorganic Chemistry. Bioorganic Chemistry 39 96 .
Irina I. Karuzina & Alexander I. Archakov. (1994) Hydrogen peroxide-mediated inactivation of microsomal cytochrome P450 during monooxygenase reactions. Free Radical Biology and Medicine 17:6, pages 557-567.
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Irina I. Karuzina & Alexander I. Archakov. (1994) The oxidative inactivation of cytochrome P450 in monooxygenase reactions. Free Radical Biology and Medicine 16:1, pages 73-97.
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