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Drug Metabolism Reviews Volume 20, 1989 - Issue 2-4
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Research Article

Ca2+ Activated Mechanisms in Cell Killing

Pierluigi Nicotera Department of Toxicology, Karolinska Institutet, Box 60 400, S-104 01, Stockholm, Sweden
,
David J. Mc Conkey Department of Toxicology, Karolinska Institutet, Box 60 400, S-104 01, Stockholm, Sweden
,
Jeannette M. Dypbukt Department of Toxicology, Karolinska Institutet, Box 60 400, S-104 01, Stockholm, Sweden
,
Dean P. Jones Department of Toxicology, Karolinska Institutet, Box 60 400, S-104 01, Stockholm, Sweden
&
Sten Orrenius Department of Toxicology, Karolinska Institutet, Box 60 400, S-104 01, Stockholm, Sweden
Pages 193-201 | Published online: 22 Sep 2008

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Eric Chamberlin & Guochuan E. Tsai. (1998) A Glutamatergic Model of ECT-induced Memory Dysfunction. Harvard Review of Psychiatry 5:6, pages 307-317.
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Xiaonian Yang & RickG. Schnellmann. (1996) PROTEINASES IN RENAL CELL DEATH. Journal of Toxicology and Environmental Health 48:4, pages 319-332.
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Claire M. Payne, Carol Bernstein & Harris Bernstein. (1995) Apoptosis Overview Emphasizing the Role of Oxidative Stress, DNA Damage and Signal- Transduction Pathways. Leukemia & Lymphoma 19:1-2, pages 43-93.
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I. Szumiel. (1994) Ionizing Radiation-induced Cell Death. International Journal of Radiation Biology 66:4, pages 329-341.
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N.I. Sorokina, N.B. Pushkareva, A.V. Nikolsky, M.F. Denisenko & I.V. Filippovich. (1992) Accumulation of CAMP in γ-irradiated Thymocytes and Internucleosomal DNA Fragmentation. International Journal of Radiation Biology 62:5, pages 603-612.
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Articles from other publishers (45)

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Bruce R. Ransom, Mark P. Goldberg, Ken Arai & Selva Baltan. 2016. Stroke. Stroke 113 128 .
Bruce R. Ransom, Mark P. Goldberg & Selva Baltan. 2011. Stroke. Stroke 122 137 .
Sung Ju LeeChae Hwa KwonYong Keun Kim. (2009) Alterations in Membrane Transport Function and Cell Viability Induced by ATP Depletion in Primary Cultured Rabbit Renal Proximal Tubular Cells. The Korean Journal of Physiology and Pharmacology 13:1, pages 15.
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M. Mozaffarieh, M.C. Grieshaber, S. Orgül & J. Flammer. (2008) The Potential Value of Natural Antioxidative Treatment in Glaucoma. Survey of Ophthalmology 53:5, pages 479-505.
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Bruce R. Ranson, Aninda B. Acharya & Mark P. Goldberg. 2004. Stroke. Stroke 867 881 .
Susan J. Hemmings, Vivian B. Pulga, Sam T. Tran & Richard R.E. Uwiera. (2001) Differential inhibitory effects of carbon tetrachloride on the hepatic plasma membrane, mitochondrial and endoplasmic reticular calcium transport systems: implications to hepatotoxicity. Cell Biochemistry and Function 20:1, pages 47-59.
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Lorenzo Lusini, Ranieri Rossi, Daniela Giustarini & Paolo Di Simplicio. (2002) The pro-oxidant role of protein SH groups of hemoglobin in rat erythrocytes exposed to menadione. Chemico-Biological Interactions 139:1, pages 97-114.
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RA Franklin & JA McCubrey. (2000) Kinases: positive and negative regulators of apoptosis. Leukemia 14:12, pages 2019-2034.
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P.J. Hughes, H. McLellan, D.A. Lowes, S.Zafar Kahn, J.G. Bilmen, S.C. Tovey, R.E. Godfrey, R.H. Michell, C.J. Kirk & F. Michelangeli. (2000) Estrogenic Alkylphenols Induce Cell Death by Inhibiting Testis Endoplasmic Reticulum Ca2+ Pumps. Biochemical and Biophysical Research Communications 277:3, pages 568-574.
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Arun L Jadhav, Govindarajan T Ramesh & Palur G Gunasekar. (2000) Contribution of protein kinase C and glutamate in Pb2+-induced cytotoxicity. Toxicology Letters 115:2, pages 89-98.
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Peter L. Carlen, Marc R. Pelletier, Aviv Ouanounou, Michael Tymianski & Liang Zhang. 2002. Intractable Seizures. Intractable Seizures 209 224 .
David Sindram, Vivek Kohli, John F. Madden & Pierre-Alain Clavien. (1999) CALPAIN INHIBITION PREVENTS SINUSOIDAL ENDOTHELIAL CELL APOPTOSIS IN THE COLD ISCHEMIC RAT LIVER1,2. Transplantation 68:1, pages 136-140.
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Toru Matsui, Toshiaki Nagafuji, Toshiro Kumanishi & Takao Asano. (1999) Role of Nitric Oxide in Pathogenesis Underlying Ischemic Cerebral Damage. Cellular and Molecular Neurobiology 19:1, pages 177-189.
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Viganò L.A. Arillo, C. Falugi & F. Melodia. (1998) Histochemical and biochemical markers in trout larvae exposed to river sediments. Chemosphere 37:14-15, pages 2797-2807.
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Mokdad Mezna & Francesco Michelangeli. (1998) The role of inorganic phosphate in regulating the kinetics of inositol 1,4,5-trisphosphate-induced Ca 2+ release: a putative role for endoplasmic reticulum phosphate transporters. Biochimica et Biophysica Acta (BBA) - Biomembranes 1373:1, pages 270-276.
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Jonathan F. McAnulty. (1998) The Effect of Calcium on Hypothermia-Facilitated Resuscitation of Warm Ischemic Kidney Tissue Slices: A Role for the Mitochondrial Permeability Transition Pore?. Cryobiology 36:1, pages 12-19.
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Vivek Kohli, Wenshi Gao, Carlos A. CamargoJr.Jr. & Pierre Alain Clavien. (1997) Calpain is a mediator of preservation-reperfusion injury in rat liver transplantation. Proceedings of the National Academy of Sciences 94:17, pages 9354-9359.
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Stefan Peuchen, Juan P. Bolaños, Simon J.R. Heales, Angeles Almeida, Michael R. Duchen & John B. Clark. (1997) Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system. Progress in Neurobiology 52:4, pages 261-281.
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James Kevin Chipman. 1997. Molecular and Cellular Pharmacology. Molecular and Cellular Pharmacology 1033 1049 .
Sophie Lelièvre, Valerie M. Weaver, Carolyn A. Larabell & Mina J. Bissell. 1997. Cell Structure and Signaling. Cell Structure and Signaling 1 55 .
Yolande Chvatchko, Soledad Valera, Jean-Pierre Aubry, Toufic Renno, Gary Buell & Jean-Yves Bonnefoy. (1996) The Involvement of an ATP-Gated Ion Channel, P2X1, in Thymocyte Apoptosis. Immunity 5:3, pages 275-283.
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Hsing Hong Chen & H. Mei Liu. (1996) A new fluorescent histological marker for ischemic neurons, EA 50: Correlated with Fos and Jun/ AP-1 immunoreactivity. Histochemistry and Cell Biology 105:5, pages 375-382.
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Anthony F. D'Andrea, S. E. Stancyk & G. T. Chandler. (1996) Sublethal effects of cadmium on arm regeneration in the burrowing brittlestar, Microphiopholis gracillima. Ecotoxicology 5:2, pages 115-133.
Crossref
A. Viarengo, R. Accomando, I. Ferrando, F. Beltrame, M. Fato & G. Marcenaro. (1996) Heavy metal effects on cytosolic free Ca2+ level in the marine protozoan Euplotes crassus evaluated by confocal laser scanning microscopy. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 113:2, pages 161-168.
Crossref
Mario E. Götz, Gabriella Künig, Peter Riederer & Moussa B.H. Youdim. 1996. Chemical Factors in Neural Growth, Degeneration and Repair. Chemical Factors in Neural Growth, Degeneration and Repair 425 509 .
R F OmarN DusserreA DésormeauxL PoulinM TremblayD BeauchampM G Bergeron. (1995) Liposomal encapsulation of foscarnet protects against hypocalcemia induced by free foscarnet. Antimicrobial Agents and Chemotherapy 39:9, pages 1973-1978.
Crossref
E. Escuret. (1995) La cascade ischémique cérébrale. Annales Françaises d'Anesthésie et de Réanimation 14:1, pages 103-113.
Crossref
H. Mei Liu. 1995. Gene Expression in The Central Nervous System. Gene Expression in The Central Nervous System 239 244 .
Jan N. Johannessen. 1995. Neurotoxicology. Neurotoxicology 399 421 .
A. Viarengo, L. Canesi, M. N. Moore & M. Orunesu. (1994) Effects of Hg2+ and Cu2+ on the cytosolic Ca2+ level in molluscan blood cells evaluated by confocal microscopy and spectrofluorimetry. Marine Biology 119:4, pages 557-564.
Crossref
V.L. Woodburn & G.N. Woodruff. 1994. 1 33 .
Akhlaq A. Farooqui & Lloyd A. Horrocks. 1994. 267 323 .
Mario E. Götz, Gabriella Künig, Peter Riederer & Moussa B.H. Youdim. (1994) Oxidative stress: Free radical production in neural degeneration. Pharmacology & Therapeutics 63:1, pages 37-122.
Crossref
M. Kretzschmar. 1994. Sepsis. Sepsis 122 135 .
A. Viarengo, G. Mancinelli, M. Pertica, R. Fabbri & M. Orunesu. (1993) Effects of heavy metals on the Ca2+-ATPase activity present in gill cell plasma-membrane of mussels (Mytilus galloprovincialis Lam.). Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 106:3, pages 655-660.
Crossref
C SteenbergenM E PerlmanR E LondonE Murphy. (1993) Mechanism of preconditioning. Ionic alterations.. Circulation Research 72:1, pages 112-125.
Crossref
Ulrich Dirnagl. 1993. Neurobiology of Ischemic Brain Damage. Neurobiology of Ischemic Brain Damage 49 65 .
S. Rose, J. Dike, V. Bühren, O. Trentz & M. M. Sayeed. 1993. Host Defense Dysfunction in Trauma, Shock and Sepsis. Host Defense Dysfunction in Trauma, Shock and Sepsis 517 522 .
Dennis W. Choi. (2004) Excitotoxic cell death. Journal of Neurobiology 23:9, pages 1261-1276.
Crossref
Akhlaq A. Farooqui & Lloyd A. Horrocks. (1991) Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders. Brain Research Reviews 16:2, pages 171-191.
Crossref
Charles D. Deakin, Elizabeth A. Fagan & Roger Williams. (1991) Cytoprotective effects of calcium channel blockers. Journal of Hepatology 12:2, pages 251-255.
Crossref
Mohammad Q. Hassan, Intisar T. Numan, Nazar Al-Nasiri & Sidney J. Stohs. (2016) Endrin-Induced Histopathological Changes and Lipid Peroxidation in Livers and Kidneys of Rats, Mice, Guinea Pigs and Hamsters. Toxicologic Pathology 19:2, pages 108-114.
Crossref
A. Viarengo & P. Nicotera. (1991) Possible role of ca2+ in heavy metal cytotoxicity. Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 100:1-2, pages 81-84.
Crossref
P.J. O'Brien. (1991) Molecular mechanisms of quinone cytotoxicity. Chemico-Biological Interactions 80:1, pages 1-41.
Crossref

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