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Research Article

Stereochemistry of Cytochrome P-450 Reactions

Pages 489-496 | Published online: 22 Sep 2008

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Hong Lu. (2007) Stereoselectivity in drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 149-158.
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Lukas Gebauer, Ole Jensen, Muhammad Rafehi & Jürgen Brockmöller. (2023) Stereoselectivity in Cell Uptake by SLC22 Organic Cation Transporters 1, 2, and 3. Journal of Medicinal Chemistry.
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R. S. Foti & D. K. Dalvie. (2016) Cytochrome P450 and Non-Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics. Drug Metabolism and Disposition 44:8, pages 1229-1245.
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Marco Girhard, Patrick J. Bakkes, Osama Mahmoud & Vlada B. Urlacher. 2015. Cytochrome P450. Cytochrome P450 451 520 .
Takako Harada, Koki Fujita, Jun Shigeto & Yuji Tsutsumi. (2014) Stereo-selective oxidations of terpinolene by cytochrome P450 monooxygenases in the microsomal fraction of Cupressus lusitanica cultured cells. Journal of Wood Science 60:6, pages 446-452.
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Alexander V. LyubimovLarry C. Wienkers & Guy E. Padbury. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 30 .
Robert J. Greene, John A. Davis, Raju Subramanian, Molly R. Deane, Maurice G. Emery & J. Greg Slatter. (2012) Regiospecific and Stereospecific Triangulation of the Structures of Metabolites Formed by Sequential Metabolism at Multiple Prochiral Centers. Drug Metabolism and Disposition 40:5, pages 928-942.
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V.B. Urlacher. 2012. Comprehensive Chirality. Comprehensive Chirality 275 294 .
Hanqing Dong, Xiaochuan Guo & Zengbiao Li. 2011. Chiral Drugs. Chiral Drugs 347 379 .
John Timbrell. 2008. Principles of Biochemical Toxicology, Fourth Edition. Principles of Biochemical Toxicology, Fourth Edition 75 127 .
Dion R. Brocks. (2006) Drug disposition in three dimensions: an update on stereoselectivity in pharmacokinetics. Biopharmaceutics & Drug Disposition 27:8, pages 387-406.
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Shuji Ohhira, Mitsunori Enomoto & Hisao Matsui. (2006) Sex difference in the principal cytochrome P-450 for tributyltin metabolism in rats. Toxicology and Applied Pharmacology 210:1-2, pages 32-38.
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Arun K. Agrawal, Cornelis E.C.A. Hop, Jianmei Pang, Maria V. Silva Elipe, Ranjit C. Desai, Kwan H. Leung & Ronald B. Franklin. (2005) In vitro metabolism of a new oxazolidinedione hypoglycemic agent utilizing liver microsomes and recombinant human cytochrome P450 enzymes. Journal of Pharmaceutical and Biomedical Analysis 37:2, pages 351-358.
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Shuji Ohhira, Masatomo Watanabe & Hisao Matsui. (2004) Identification of principal cytochrome P-450 in triphenyltin metabolism in rats. Toxicology Letters 148:1-2, pages 141-148.
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Laurence S. Kaminsky & Zhi-Yi Zhang. (1997) Human P450 metabolism of warfarin. Pharmacology & Therapeutics 73:1, pages 67-74.
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Etienne Benoît, Thierry Buronfosse & Paul Delatour. (2004) Effect of cytochrome P‐450 1A induction on enantioselective metabolism and pharmacokinetics of an aryltrifluoromethyl sulfide in the rat. Chirality 6:5, pages 372-377.
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E.J. Ari?ns. (1993) Nonchiral, homochiral and composite chiral drugs. Trends in Pharmacological Sciences 14:2, pages 68-75.
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Satish I. Rao & Michael W. Duffel. (2004) Benzylic alcohols as stereospecific substrates and inhibitors for aryl sulfotransferase. Chirality 3:2, pages 104-111.
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