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Research Article

Udp-Glucuronosyltrans-Ferases in the Metabolic Disposition of Xenobiotics

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Pages 689-695 | Published online: 22 Sep 2008

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M.S. Yang, W.F. Fong, T.C. Chan, V.W.D. Chui & M.H. Wong. (1993) Feasibility studies on the use of sewage sludge as supplementary feed for rearing tilapia II. PCBs of the treated fish, and biochemical response in the fish liver. Environmental Technology 14:12, pages 1163-1169.
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R. G. Dickinson, R. K. Verbeeck & A. R. King. (1991) Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat. Xenobiotica 21:11, pages 1535-1546.
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Z Ben-Zvi, F Hreash & J Kaplanski. (1991) Disposition of Hexobarbitone and Antipyrine in DOCA-hypertensive Rats. Journal of Pharmacy and Pharmacology 43:5, pages 349-352.
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K Walton, J.L Dorne & A.G Renwick. (2001) Uncertainty factors for chemical risk assessment: interspecies differences in glucuronidation. Food and Chemical Toxicology 39:12, pages 1175-1190.
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Mohammad Athar, S. Zakir Husain & Nafisul Hasan. 1997. Liver and Environmental Xenobiotics. Liver and Environmental Xenobiotics 19 30 .
K. H. Moore, R. H. Raasch, K. L. Brouwer, K. Opheim, S. H. Cheeseman, E. Eyster, S. M. Lemon & C. M. van der Horst. (1995) Pharmacokinetics and bioavailability of zidovudine and its glucuronidated metabolite in patients with human immunodeficiency virus infection and hepatic disease (AIDS Clinical Trials Group protocol 062). Antimicrobial Agents and Chemotherapy 39:12, pages 2732-2737.
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JESPER SONNE. (1993) FACTORS AND CONDITIONS AFFECTING THE GLUCURONIDATION OF OXAZEPAM. Pharmacology & Toxicology 73, pages 1-23.
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Achim Schmoldt, Ingbert Bl�mer & Andrea Johannes. (1992) Hydroxysteroid sulfotransferase and a specific UDP-glucuronosyltransferase are involved in the metabolism of digitoxin in man. Naunyn-Schmiedeberg's Archives of Pharmacology 346:2, pages 226-233.
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R.R. Drake, P. Zimniak, B.E. Haley, R. Lester, A.D. Elbein & A. Radominska. (1991) Synthesis and characterization of 5-azido-UDP-glucuronic acid. A new photoaffinity probe for UDP-glucuronic acid-utilizing proteins.. Journal of Biological Chemistry 266:34, pages 23257-23260.
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Andrew R. King & Ronald G. Dickinson. (1991) Studies on the reactivity of acyl glucuronides—I. Biochemical Pharmacology 42:12, pages 2289-2299.
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Ki H. Kim. (1991) Quantitative Structure-Activity Relationships of the Metabolism of Drugs by Uridine Diphosphate Glucuronosyltransferase. Journal of Pharmaceutical Sciences 80:10, pages 966-970.
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Anastacio M. Hoyumpa & Steven Schenker. (1991) Is glucuronidation truly preserved in patients with liver disease?. Hepatology 13:4, pages 786-795.
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P. J. Swart, F. G. A. Jansman, B. F. H. Drenth, R. A. de Zeeuw, D. Dijkstra & A. S. Horn. (2009) Impact of Structural Differences on the in Vitro Glucuronidation Kinetics of Potentially Dopaminergic Hydroxy‐2‐Aminotetralins and Naphthoxazines Using Rat and Human Liver Microsomes . Pharmacology & Toxicology 68:3, pages 215-219.
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Thomas R. Tephly & Brian Burchell. (1990) UDP-glucuronosyltransferases: a family of detoxifying enzymes. Trends in Pharmacological Sciences 11:7, pages 276-279.
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