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Drug Metabolism Reviews Volume 20, 1989 - Issue 2-4
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Research Article

Induction of Cytochromes P-450b/E By Phenobarbital in Primary Culture of Adult Rat Hepatocytes: Test of Differentiated Uver Gene Expression

Philip s. Guzelian Departments of Medicine and Pathology, Medical College of Virginia, Richmond, Virginia, 23298-0267
,
Donna Li Departments of Medicine and Pathology, Medical College of Virginia, Richmond, Virginia, 23298-0267
&
Erin G. Schuetz Departments of Medicine and Pathology, Medical College of Virginia, Richmond, Virginia, 23298-0267
Pages 793-809 | Published online: 22 Sep 2008

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Mont R. Juchau, Qwihee P. Lee & Alan G. Fantel. (1992) Xenobiotic Biotransfor Mation/Bioactivation in Organogenesis-Stage Conceptal Tissues: Implications for Embryotoxicity and Teratogenesis. Drug Metabolism Reviews 24:2, pages 195-238.
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Articles from other publishers (13)

M. Helen Grant, Caroline Morgan, Catherine Henderson, G�nther Malsch, Barbara Seifert, Wolfgang Albrecht & Thomas Groth. (2005) The viability and function of primary rat hepatocytes cultured on polymeric membranes developed for hybrid artificial liver devices. Journal of Biomedical Materials Research Part A 73A:3, pages 367-375.
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Julio C. Davila & Dale L. Morris. (1999) Analysis of cytochrome P450 and phase II conjugating enzyme expression in adult male rat hepatocytes. In Vitro Cellular & Developmental Biology - Animal 35:3, pages 120-130.
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K. Anderson, L. Yin, C. Macdonald & M.H. Grant. (1996) Immortalized hepatocytes as in vitro model systems for toxicity testing: the comparative toxicity of menadione in immortalized cells, primary cultures of hepatocytes and HTC hepatoma cells. Toxicology in Vitro 10:6, pages 721-727.
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Patricia Watts, Mark D. Smith, Ian Edwards, Victor Zammit, Vivienne Brown & Helen Grant. (1995) The influence of medium composition on the maintenance of cytochrome P-450, glutathione content and urea synthesis: a comparison of rat and sheep primary hepatocyte cultures. Journal of Hepatology 23:5, pages 605-612.
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M.J.M. Toussaint & H. Nederbragt. (1995) Lack of effect of extracellular matrix or 3T3 feeder layer on the maintenance of differentiation or survival time of cultured rat hepatocytes. Toxicology in Vitro 9:1, pages 83-90.
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Thierry Fournier, Najet Mejdoubi, Dagui Monnet, Geneviève Durand & Dominique Porquet. (1994) Phenobarbital induction of α1-acid glycoprotein in primary rat hepatocyte cultures. Hepatology 20:6, pages 1584-1588.
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A J Strain. (1994) Isolated hepatocytes: use in experimental and clinical hepatology.. Gut 35:4, pages 433-436.
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Hamed Doostdar, M. Helen Grant, William T. Melvin, Roland Wolf & M. Danny Burke. (1993) The effects of inducing agents on cytochrome P450 and UDP-glucuronyltransferase activities in human HEPG2 hepatoma cells. Biochemical Pharmacology 46:4, pages 629-635.
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Susanna S.T. Lee & Jeffrey G. Scott. (1992) In vitro induction of microsomal cytochrome P-450 monooxygenases by phenobarbital in fat bodies of adult house fly, Musca domestica L.. Insect Biochemistry and Molecular Biology 22:7, pages 691-698.
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Nathalie PERROT, Christophe CHESNÉ, Isabelle DE WAZIERS, Joseph CONNER, Philippe Henri BEAUNE & André GUILLOUZO. (2005) Effects of ethanol and clofibrate on expression of cytochrome P ‐450 enzymes and epoxide hydrolase in cultures and cocultures of rat hepatocytes . European Journal of Biochemistry 200:1, pages 255-261.
Crossref
. 1991. Isolated Hepatocytes Preparation, Properties and Applications. Isolated Hepatocytes Preparation, Properties and Applications 409 439 .
Donna Li, Erin G. Schuetz & Philip S. Guzelian. 1991. Cytochrome P450. Cytochrome P450 335 344 .
Michael Balls, Michael Garle & Richard Clothier. 1991. Animals and Alternatives in Toxicology. Animals and Alternatives in Toxicology 313 339 .

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