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Research Article

Cytochrome P450IIe1: Roles in Nitrosamine Metabolism and Mechanisms of Regulation

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Pages 147-159 | Published online: 22 Sep 2008

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Pat Neafsey, Gary Ginsberg, Dale Hattis, Douglas O. Johns, Kathryn Z. Guyton & Babasaheb Sonawane. (2009) Genetic Polymorphism in CYP2E1: Population Distribution of CYP2E1 Activity. Journal of Toxicology and Environmental Health, Part B 12:5-6, pages 362-388.
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Arthur Cederbaum. (2009) Nrf2 and antioxidant defense against CYP2E1 toxicity. Expert Opinion on Drug Metabolism & Toxicology 5:10, pages 1223-1244.
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Chantey R. Morris, Sheng C. Chen, Lin Zhou, Lawrence M. Schopfer, Xinxin Ding & Sidney S. Mirvish. (2004) Inhibition by Allyl Sulfides and Phenethyl Isothiocyanate of Methyl-n-pentylnitrosamine Depentylation by Rat Esophageal Microsomes, Human and Rat CYP2E1, and Rat CYP2A3. Nutrition and Cancer 48:1, pages 54-63.
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Salah A. Sheweita. (2004) Carcinogen-Metabolizing Enzymes and Insecticides. Journal of Environmental Science and Health, Part B 39:5-6, pages 805-818.
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Charles S. Lieber. (2004) The Discovery of the Microsomal Ethanol Oxidizing System and Its Physiologic and Pathologic Role. Drug Metabolism Reviews 36:3-4, pages 511-529.
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Charles S. Lieber. (2000) Hepatic, Metabolic, and Nutritional Disorders of Alcoholism: From Pathogenesis to Therapy. Critical Reviews in Clinical Laboratory Sciences 37:6, pages 551-584.
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G.-F. CHEN, M. J. J. RONIS, M. INGELMAN-SUNDBERG & T. M. BADGER. (1999) Hormonal regulation of microsomal cytochrome P4502E1 and P450 reductase in rat liver and kidney. Xenobiotica 29:5, pages 437-451.
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D. F. V. Lewis, P. G. Brantom, C. Ioannides, R. Walker & D. V. Parke. (1997) Nitrosamine Carcinogenesis: Rodent Assays, Quantitative Structure-Activity Relationships, and Human Risk Assessment. Drug Metabolism Reviews 29:4, pages 1055-1078.
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T. Koizumi, K. Tajima, A. Hara, N. Emi, S. Ohmori, H. Kumagai, H. Tatsumoto & K. T. Suzuki. (1995) Suppressive effect of molybdenum on hepatotoxicity of N-nitrosodiethylamine in rats. Redox Report 1:3, pages 197-203.
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Y. Kobayashi, T. Yoshida, E. Kotani, Y. Matsuura, H. Egawa, T. Aoyagi, S. Imaoka, Y. Funae, S. Tobinaga & Y. Kuroiwa. (1995) Induction of hepatic microsomal P450 by 4-phenylalkylpyridines in rat: chain length-dependent and sex-related differential induction of P450s. Xenobiotica 25:8, pages 779-789.
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S. Fadlallah, S. Cooper, M. Lachapelle, F. Denizeau, S. Mansour, F. Guertin, K. Krzystyniak & M. Fournier. (1994) Assessment of N-Nitrosodimethylamine Dna Adducts in Rat Hepatocytes by High Performance Liquid Chromatography and Immunosorbent Assay. International Journal of Environmental Analytical Chemistry 56:2, pages 165-174.
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E. Nagababu & N. Lakshmaiah. (1994) Inhibition of Microsomal Lipid Peroxidation and Monooxygenase Activities by Eugenol. Free Radical Research 20:4, pages 253-266.
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Steven A. Wrighton, Mark Vandenbranden, Jeffrey C. Stevens, Lisa A. Shipley, Barbara J. Ring, John R. Cashman & Allan E. Rettie. (1993) In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development. Drug Metabolism Reviews 25:4, pages 453-484.
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Steven A. Wrighton & Jeffrey C. Stevens. (1992) The Human Hepatic Cytochromes P450 Involved in Drug Metabolism. Critical Reviews in Toxicology 22:1, pages 1-21.
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