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Drug Metabolism Reviews Volume 23, 1991 - Issue 1-2
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Research Article

Drug Disposition in the Mammalian Eye and Brain: A Comparison of Mechanisms

Franz-Josef Leinweber Department of Drug Metabolism, Hoffmann-La Roche, Nutley, New Jersey, 07110
Pages 133-246 | Published online: 22 Sep 2008

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Upendra A. Argikar, Jennifer L. Dumouchel, Christine E. Dunne & Andrea J. Bushee. (2017) Ocular non-P450 oxidative, reductive, hydrolytic, and conjugative drug metabolizing enzymes. Drug Metabolism Reviews 49:3, pages 372-394.
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Petra Malátková & Vladimír Wsól. (2014) Carbonyl reduction pathways in drug metabolism. Drug Metabolism Reviews 46:1, pages 96-123.
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Articles from other publishers (12)

Murat Akkurt Arslan, Françoise Brignole-Baudouin, Solenne Chardonnet, Cédric Pionneau, Frédéric Blond, Christophe Baudouin & Karima Kessal. (2023) Profiling tear film enzymes reveals major metabolic pathways involved in the homeostasis of the ocular surface. Scientific Reports 13:1.
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Jatinder Kaur Mukker & Ravi Shankar Prasad Singh. (2019) Pharmacokinetic Modeling in Nano-formulations: Concept, Implementation and Challenges. Current Pharmaceutical Design 24:43, pages 5175-5180.
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Upendra A. Argikar, Jennifer L. Dumouchel, Valerie M. Kramlinger, Amanda L. Cirello, Mithat Gunduz, Christine E. Dunne & Bindi Sohal. (2017) Do We Need to Study Metabolism and Distribution in the Eye: Why, When, and Are We There Yet?. Journal of Pharmaceutical Sciences 106:9, pages 2276-2281.
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Poonam R. Velagaleti & Michael H. Buonarati. 2014. Ocular Pharmacology and Toxicology. Ocular Pharmacology and Toxicology 33 52 .
Sheila Flack & Leena A. Nylander-French. 2012. Toxicology and Human Environments. Toxicology and Human Environments 163 207 .
Abeer Al-Ghananeem & Peter Crooks. (2007) Phase I and Phase II Ocular Metabolic Activities and the Role of Metabolism in Ophthalmic Prodrug and Codrug Design and Delivery. Molecules 12:3, pages 373-388.
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Kevin M. Cooper, Robert J. McCracken & D. Glenn Kennedy. (2005) Nitrofurazone accumulates in avian eyes—a replacement for semicarbazide as a marker of abuse. The Analyst 130:6, pages 824.
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Kevin M. Cooper & D. Glenn Kennedy. (2005) Nitrofuran antibiotic metabolites detected at parts per million concentrations in retina of pigs—a new matrix for enhanced monitoring of nitrofuran abuse. The Analyst 130:4, pages 466-468.
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D. J. Smith, K. M. Ehrenfried, J. D. Dalidowicz & M. P. Turberg. (2002) Binding of ractopamine HCl to ocular tissues of cattle and turkeys in vivo and to melanin in vitro1,2. Journal of Animal Science 80:11, pages 2931-2941.
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Colleen M.Walsh Clang & Michael D. Aleo. (1997) Mechanistic Analysis ofS-(1,2-Dichlorovinyl)-l-cysteine-Induced Cataractogenesisin Vitro. Toxicology and Applied Pharmacology 146:1, pages 144-155.
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Cong Zhao & Hitoshi Shichi. (1995) Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues. Experimental Eye Research 60:2, pages 143-152.
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Tadeusz Sarna. (1992) New trends in photobiology. Journal of Photochemistry and Photobiology B: Biology 12:3, pages 215-258.
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