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Drug Metabolism Reviews Volume 23, 1991 - Issue 3-4
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Research Article

Stereoselectivity of Glutathione Conjugation In Vivo, In the Perfused Liver and in Isolated Hepatocytes

Gerard J. Mulder Division of Toxicology, Center for Biopharmaceutical Sciences, University of Leiden, Leiden, The Netherlands; Faculty of Pharmacy, University of Toronto, Toronto, Canada
,
Johan M. Te Koppele Division of Toxicology, Center for Biopharmaceutical Sciences, University of Leiden, Leiden, The Netherlands; Faculty of Pharmacy, University of Toronto, Toronto, Canada
,
Co G. M. Schipper Division of Toxicology, Center for Biopharmaceutical Sciences, University of Leiden, Leiden, The Netherlands; Faculty of Pharmacy, University of Toronto, Toronto, Canada
,
Wilco H. M. Snel Division of Toxicology, Center for Biopharmaceutical Sciences, University of Leiden, Leiden, The Netherlands; Faculty of Pharmacy, University of Toronto, Toronto, Canada
,
K. Sandy Pang Division of Toxicology, Center for Biopharmaceutical Sciences, University of Leiden, Leiden, The Netherlands; Faculty of Pharmacy, University of Toronto, Toronto, Canada
&
Martine Polhuijs Division of Toxicology, Center for Biopharmaceutical Sciences, University of Leiden, Leiden, The Netherlands; Faculty of Pharmacy, University of Toronto, Toronto, Canada
Pages 311-330 | Published online: 22 Sep 2008

Citations (5)

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Read on this site (2)

A. BADER, N. FRUHAUF, K. ZECH, A. HAVERICH & J. T. BORLAK. (1998) Development of a small-scale bioreactor for drug metabolism studies maintaining hepatospecific functions. Xenobiotica 28:9, pages 815-825.
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Johan M. Te Koppele & Gerard J. Mulder. (1991) Stereoselective Glutathione Conjugation by Subcellular Fractions and Purified Glutathione S-Transferases. Drug Metabolism Reviews 23:3-4, pages 331-354.
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Articles from other publishers (3)

Piet J.M. Boon, H.Susana Marinho, Roelof Oosting & Gerard J. Mulder. (1999) Glutathione Conjugation of 4-Hydroxy-trans-2,3-nonenal in the Rat in Vivo, the Isolated Perfused Liver and Erythrocytes. Toxicology and Applied Pharmacology 159:3, pages 214-223.
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Monica Mestre I. Viver, J.Fred Nagelkerke & Gerard J. Mulder. (1992) Stereospecific glutathione conjugation of (R)- and (S)-2-bromoisovalerylurea in freshly isolated rat kidney proximal tubular cells. Biochemical Pharmacology 43:4, pages 902-904.
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C.A. Wilco Snel, Sivi Mahadevan, Martine Polhuijs & Gerard J. Mulder. (2004) Glutathione conjugation and pharmacokinetics of 2‐bromo‐3‐phenylpropionic acid in vitro and in the rat in vivo. Chirality 4:7, pages 407-414.
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