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Research Article

CYP1A1: Friend or Foe?

Pages 503-517 | Published online: 22 Sep 2008

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Neha Gupta, Omar Al Ustwani, Li Shen & Roberto Pili. (2014) Mechanism of action and clinical activity of tasquinimod in castrate-resistant prostate cancer. OncoTargets and Therapy 7, pages 223-234.
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Prajwal P Nandekar & Abhay T Sangamwar. (2012) Cytochrome P450 1A1-mediated anticancer drug discovery: in silico findings. Expert Opinion on Drug Discovery 7:9, pages 771-789.
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Cheri M Turman, Jade M Hatley, Daniel J Ryder, Vijayalakshmi Ravindranath & Henry W Strobel. (2006) Alternative splicing within the human cytochrome P450 superfamily with an emphasis on the brain: the convolution continues. Expert Opinion on Drug Metabolism & Toxicology 2:3, pages 399-418.
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Jukka Hakkola, Olavi Pelkonen, Markku Pasanen & Hannu Raunio. (1998) Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity. Critical Reviews in Toxicology 28:1, pages 35-72.
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A. P. BERESFORD*W. J. ELLIS, J. AYRTON, M. A. JOHNSON & D. F. V. LEWIS. (1997) Cytochrome P4501A(CYP1A) induction in rat and man by the benzodioxino derivative, fluparoxan. Xenobiotica 27:2, pages 159-173.
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N. R. Coelho, A. B. Pimpão, M. J. Correia, T. C. Rodrigues, E. C. Monteiro, J. Morello & S. A. Pereira. (2021) Pharmacological blockage of the AHR-CYP1A1 axis: a call for in vivo evidence. Journal of Molecular Medicine 100:2, pages 215-243.
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Rahul Sharma & Neelakantan Arumugam. (2021) N-alkylamides of Spilanthes (syn: Acmella): Structure, purification, characterization, biological activities and applications – a review. Future Foods 3, pages 100022.
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Kurt A. Gust, Karl J. Indest, Guilherme Lotufo, Steven J. Everman, Carina M. Jung, Mark L. Ballentine, Allison V. Hoke, Bintu Sowe, Aarti Gautam, Rasha Hammamieh, Qing Ji & Natalie D. Barker. (2021) Genomic investigations of acute munitions exposures on the health and skin microbiome composition of leopard frog (Rana pipiens) tadpoles. Environmental Research 192, pages 110245.
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Mohammad Karimian, Mohaddeseh Behjati, Erfaneh Barati, Tayyebeh Ehteram & Ali Karimian. (2020) CYP1A1 and GSTs common gene variations and presbycusis risk: a genetic association analysis and a bioinformatics approach. Environmental Science and Pollution Research 27:34, pages 42600-42610.
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Yongzhan Mai, Songyao Peng, Haiyan Li & Zini Lai. (2019) Histological, biochemical and transcriptomic analyses reveal liver damage in zebrafish (Danio rerio) exposed to phenanthrene. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 225, pages 108582.
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Yu Jin, Jingbo Wang, Maulana Bachtiar, Samuel S. Chong & Caroline G. L. Lee. (2018) Architecture of polymorphisms in the human genome reveals functionally important and positively selected variants in immune response and drug transporter genes. Human Genomics 12:1.
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Rajni Sharma, Ibidapo S. Williams, Linda Gatchie, Vinay R. Sonawane, Bhabatosh Chaudhuri & Sandip B. Bharate. (2018) Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. Bioorganic & Medicinal Chemistry 26:23-24, pages 6076-6086.
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YunJeong Kim, Yongchul Lim & Eunil Lee. (2017) CARM1 is involved in CYP1A1 gene expression as a transcriptional coactivator. Molecular & Cellular Toxicology 13:3, pages 263-270.
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Prajwal P. Nandekar, Kailas Khomane, Vikas Chaudhary, Vijay P. Rathod, Roshan M. Borkar, Murali Mohan Bhandi, R. Srinivas, Abhay T. Sangamwar, Sankar K. Guchhait & Arvind K. Bansal. (2016) Identification of leads for antiproliferative activity on MDA-MB-435 human breast cancer cells through pharmacophore and CYP1A1-mediated metabolism. European Journal of Medicinal Chemistry 115, pages 82-93.
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Bhagavatula Moorthy, Chun Chu & Danielle J. Carlin. (2015) Polycyclic Aromatic Hydrocarbons: From Metabolism to Lung Cancer. Toxicological Sciences 145:1, pages 5-15.
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Jin-Yan Chen, Wan-Nan Chen, Bo-Yan Jiao, Wan-Song Lin, Yun-Li Wu, Ling-Ling Liu & Xu Lin. (2014) Hepatitis B spliced protein (HBSP) promotes the carcinogenic effects of benzo [alpha] pyrene by interacting with microsomal epoxide hydrolase and enhancing its hydrolysis activity. BMC Cancer 14:1.
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Kuo-Feng Hua, Pei-Chun Liao, Zhanxiong Fang, Feng-Ling Yang, Yu-Liang Yang, Yi-Lin Chen, Yi-Chich Chiu, May-Lan Liu, Yulin Lam & Shih-Hsiung Wu. (2013) Generation of Reactive Oxygen Species by Polyenylpyrroles Derivatives Causes DNA Damage Leading to G2/M Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma Cells. PLoS ONE 8:6, pages e67603.
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Feng-mao Huang, Han-chun Chen, Md. Asaduzzaman Khan, Fu-lan Yang, Xin-xing Wan, Ai-hua Xu, Fang-dan Ou-yang & Dian-zheng Zhang. (2013) CYP2A6, CYP1A1, and CYP2D6 polymorphisms in lung cancer patients from Central South China. Medical Oncology 30:2.
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Tomohide Uno, Satoru Kaji, Tatsushi Goto, Hiromasa Imaishi, Masahiko Nakamura, Kengo Kanamaru, Hiroshi Yamagata, Yoshio Kaminishi & Takao Itakura. (2011) Metabolism of the herbicides chlorotoluron, diuron, linuron, simazine, and atrazine by CYP1A9 and CYP1C1 from Japanese eel (Anguilla japonica). Pesticide Biochemistry and Physiology 101:2, pages 93-102.
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Tomohide Uno, Sota Okamoto, Satoko Masuda, Hiromasa Imaishi, Masahiko Nakamura, Kengo Kanamaru, Hiroshi Yamagata, Mohamed A.H. El-Kady, Yoshio Kaminishi & Takao Itakura. (2008) Bioconversion by functional P450 1A9 and P450 1C1 of Anguilla japonica. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 147:3, pages 278-285.
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