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Drug Metabolism Reviews Volume 26, 1994 - Issue 1-2
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Research Article

Metabolic N-Oxidation of Diarylimines: A New Metabolic Reaction of Potential Toxicological Significance

J. W. Gorrod Chelsea Department of Pharmacy, Kings College London, Manresa Road, London, SW3 6LX, United Kingdom
&
M. Ulgen Chelsea Department of Pharmacy, Kings College London, Manresa Road, London, SW3 6LX, United Kingdom
Pages 241-252 | Published online: 22 Sep 2008

Citations (10)

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Read on this site (1)

M. Ulgen, J. W. Gorrod & D. Barlow. (1994) Structure-activity relationships in the formation of amides from substituted N-benzylanilines. Xenobiotica 24:8, pages 735-748.
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Articles from other publishers (9)

Mert Ulgen & John W Gorrod. (1996) The Failure of Substrate pKa to Influence the Microsomal Formation of Amides from N -Benzylamines: the Microsomal Metabolism of N -Benzyl Pyrrolidine, N -Benzyl Carbazole and N -Acetyl- N -benzyl-4-methylaniline . Journal of Pharmacy and Pharmacology 48:12, pages 1320-1326.
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Chian-Ming Low M Ulgen & J W Gorrod. (1994) The Recognition of a Diarylimine as a Metabonate Produced During Incubation of N -Benzyl-4-chloroaniline with Hepatic Microsomal Preparations . Journal of Pharmacy and Pharmacology 46:7, pages 585-590.
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Peter Hlavica & Michael Lehnerer. 2009. PATAI'S Chemistry of Functional Groups. PATAI'S Chemistry of Functional Groups.
Yunhui Wu, James T. Farrell, Kari Lynn, Danielle Euler, Gloria Kwei, Tsang-Lin Hwang & Xue-Zhi Qin. (2002) The Importance of Chromatographic Separation in LC/MS/MS Quantitation of Drugs in Biological Fluids:  Detection, Characterization, and Synthesis of a Previously Unknown Low-Level Nitrone Metabolite of a Substance P Antagonist. Analytical Chemistry 75:3, pages 426-434.
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M. Ülgen & J. W. Gorrod. (2000) Studies on thein vitro hepatic microsomal formation of amides during the metabolism of certain secondary and tertiary benzylic amines. European Journal of Drug Metabolism and Pharmacokinetics 25:2, pages 145-150.
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F. Yılmaz, M. Ulgen & J.W. Gorrod. (1999) THE IN VITRO HEPATIC MICROSOMAL METABOLISM OF N-BENZYLADAMANTANAMINE IN RATS. Drug Metabolism and Drug Interactions 15:2-3.
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I. Küçükgüzel, M. Ülgen & J. W. Gorrod. (1997) In vitro microsomal metabolism of nuclear chloro substituted secondary amines and imines. European Journal of Drug Metabolism and Pharmacokinetics 22:4, pages 351-358.
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Mert Ulgen, Feyza Yilmaz, Seda Unsalan & John W. Gorrod. (1995) Chemical and Metabolic Studies on N-Benzyl-tert-Butylamine and its Potential Metabolites. Drug Metabolism and Drug Interactions 12:2.
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Mert Ulgen & John W. Gorrod. (1994) Metabolic and Chemical Studies on α,N-Diarylnitrones. Drug Metabolism and Drug Interactions 11:3.
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