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Drug Metabolism Reviews Volume 26, 1994 - Issue 1-2
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Research Article

Regulatory Mechanisms in the Activation of Nitrogenous Compounds by Mammalian Cytochrome P-450 Isozymes

Peter Hlavica Walther Straub-Institut für Pharmakologie und Toxikologie der Universität, D-80336, München, Germany
Pages 325-348 | Published online: 22 Sep 2008

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Yingying Guo, Linda L. Breeden, Helmut Zarbl, Bradley D. Preston & David L. Eaton. (2005) Expression of a Human Cytochrome P450 in Yeast Permits Analysis of Pathways for Response to and Repair of Aflatoxin-Induced DNA Damage. Molecular and Cellular Biology 25:14, pages 5823-5833.
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Peter Hlavica. (2002) N-OXIDATIVE TRANSFORMATION OF FREE AND N-SUBSTITUTED AMINE FUNCTIONS BY CYTOCHROME P450 AS MEANS OF BIOACTIVATION AND DETOXICATION. Drug Metabolism Reviews 34:3, pages 451-477.
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B. Clement & F. Jung. (1995) N-hydroxylation and N-dealkylation by P4502C3 of N-methylbenzamidine: N-oxygenation and N-oxidative dealkylation of one functional group. Xenobiotica 25:5, pages 443-455.
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Articles from other publishers (6)

Joseph Locker. 2015. Liver Regeneration. Liver Regeneration 199 212 .
Patrik Rydberg, Martin S. Jørgensen, Thomas A. Jacobsen, Anne-Marie Jacobsen, Kim G. Madsen & Lars Olsen. (2013) Nitrogen Inversion Barriers Affect the N-Oxidation of Tertiary Alkylamines by Cytochromes P450. Angewandte Chemie International Edition 52:3, pages 993-997.
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Patrik Rydberg, Martin S. Jørgensen, Thomas A. Jacobsen, Anne‐Marie Jacobsen, Kim G. Madsen & Lars Olsen. (2012) Nitrogen Inversion Barriers Affect the N‐Oxidation of Tertiary Alkylamines by Cytochromes P450. Angewandte Chemie 125:3, pages 1027-1031.
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Peter Hlavica. (2006) Functional interaction of nitrogenous organic bases with cytochrome P450: A critical assessment and update of substrate features and predicted key active-site elements steering the access, binding, and orientation of amines. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1764:4, pages 645-670.
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Katja K.H. Aben, Jacqueline Cloos, Norbert P. Koper, Boudewijn J.M. Braakhuis, J. Alfred Witjes & Lambertus A.L.M. Kiemeney. (2000) Mutagen sensitivity in patients with familial and non-familial urothelial cell carcinoma. International Journal of Cancer 88:3, pages 493-496.
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J. Cloos, C.B.A. Reid, G.B. Snow & B.J.M. Braakhuis. (1996) Mutagen sensitivity: Enhanced risk assessment of squamous cell carcinoma. European Journal of Cancer Part B: Oral Oncology 32:6, pages 367-372.
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