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Original Article

Neutrophil- and Glutathione-Mediated Hepatotoxicity of α-Naphthylisothiocyanate

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Pages 153-165 | Published online: 15 Feb 2010

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Hartmut Jaeschke, Mitchell R. McGill & Anup Ramachandran. (2012) Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity. Drug Metabolism Reviews 44:1, pages 88-106.
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Alyssa M. Chandler, Sharon A. Center, John F. Randolph, Danielle L. Davignon, Sean P. McDonough & Karen L. Warner. (2019) Reference limits for hepatic bile duct-to-arteriole and bile duct-to-portal tract ratios in healthy cats. American Journal of Veterinary Research 80:1, pages 15-23.
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Kimitaka Takitani, Kanta Kishi, Hiroshi Miyazaki, Maki Koh, Hirofumi Tamaki, Akiko Inoue & Hiroshi Tamai. (2018) Altered Expression of Retinol Metabolism-Related Genes in an ANIT-Induced Cholestasis Rat Model. International Journal of Molecular Sciences 19:11, pages 3337.
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Lili Ding, Binfeng Zhang, Jinmei Li, Li Yang & Zhengtao Wang. (2017) Beneficial effect of resveratrol on α‑naphthyl isothiocyanate‑induced cholestasis via regulation of the FXR pathway. Molecular Medicine Reports.
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Hou-Qin Zhou, Wei Liu, Jian Wang, Yin-Qiu Huang, Peng-Yan Li, Yun Zhu, Jia-Bo Wang, Xiao Ma, Rui-Sheng Li, Shi-Zhang Wei, Kun Li, Hao-Tian Li, Jian-Yu Li, Xiao-He Xiao & Yan-Ling Zhao. (2017) Paeoniflorin attenuates ANIT-induced cholestasis by inhibiting apoptosis in vivo via mitochondria-dependent pathway. Biomedicine & Pharmacotherapy 89, pages 696-704.
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Yanling Zhao, Guangde Zhou, Jiabo Wang, Lei Jia, Ping Zhang, Ruisheng Li, Limei Shan, Bing Liu, Xueai Song, Shijing Liu & Xiaohe Xiao. (2013) Paeoniflorin protects against ANIT-induced cholestasis by ameliorating oxidative stress in rats. Food and Chemical Toxicology 58, pages 242-248.
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Li-Li Ding, Bin-Feng Zhang, Wei Dou, Li Yang, Chang-Sen Zhan & Zheng-Tao Wang. (2012) Protective effect of Danning tablet on acute livery injury with cholestasis induced by α-naphthylisothiocyanate in rats. Journal of Ethnopharmacology 140:2, pages 222-229.
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Yan-Ling Zhao, Jia-Bo Wang, Guang-De Zhou, Li-Mei Shan & Xiao-He Xiao. (2009) Investigations of Free Anthraquinones from Rhubarb Against α-Naphthylisothiocyanate-induced Cholestatic Liver Injury in Rats. Basic & Clinical Pharmacology & Toxicology 104:6, pages 463-469.
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Ying Zhao, Desheng Zhai, Xijing Chen, Hui He, Qin Lu & Qiaoling Yu. (2007) Protective effect of glycyrrhizin and matrine on acute vanishing bile duct syndrome induced by alpha-naphthylisothiocyanate in rats. Hepatology Research 37:2, pages 143-151.
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Ke Hu & Marilyn E. Morris. (2005) Pharmacokinetics of α-Naphthyl Isothiocyanate in Rats. Journal of Pharmaceutical Sciences 94:11, pages 2441-2451.
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Samantha E. Gad. 2005. Encyclopedia of Toxicology. Encyclopedia of Toxicology 192 193 .
Ke Hu & Marilyn E. Morris. (2004) Effects of Benzyl‐, Phenethyl‐, and α‐naphthyl Isothiocyanates on P‐glycoprotein‐ and MRP1‐mediated Transport. Journal of Pharmaceutical Sciences 93:7, pages 1901-1911.
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T. Andrew Clayton, John C. Lindon, Jeremy R. Everett, Claude Charuel, Gilles Hanton, Jean-Loic Le Net, Jean-Pierre Provost & Jeremy K. Nicholson. (2003) An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria. Archives of Toxicology 77:4, pages 208-217.
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J.R. Calvo, R.J. Reiter, J.J. Garc�a, G.G. Ortiz, D.X. Tan & M. Karbownik. (2001) Characterization of the protective effects of melatonin and related indoles against ?-naphthylisothiocyanate-induced liver injury in rats. Journal of Cellular Biochemistry 80:4, pages 461-470.
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Jeffrey W Chisholm, James R PaternitiJr.Jr. & Peter J Dolphin. (2000) Accumulation of cholestatic lipoproteins in ANIT-treated human apolipoprotein A-I transgenic rats is diminished through dose-dependent apolipoprotein A-I activation of LCAT. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1487:2-3, pages 145-154.
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Yoshiji Ohta, Mutsumi Kongo, Emi Sasaki & Nobuhiro Harada. (1999) Change in hepatic antioxidant defense system with liver injury development in rats with a single α-naphthylisothiocyanate intoxication. Toxicology 139:3, pages 265-275.
Crossref
Mutsumi Kongo, Yoshiji Ohta, Keiji Nishida, Emi Sasaki, Nobuhiro Harada & Isao Ishiguro. (1999) An association between lipid peroxidation and α-naphthylisothiocyanate-induced liver injury in rats. Toxicology Letters 105:2, pages 103-110.
Crossref

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