35
Views
16
CrossRef citations to date
0
Altmetric
Original Article

Monohydroxy Bile Acid Induced Cholestasis: Role of Biotransformation

, , &
Pages 167-181 | Published online: 15 Feb 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Stefanie Gärtner, José João Carvalho, Franziska Emmerling, Leif-Alexander Garbe & Rudolf J. Schneider. (2015) Polyclonal Murine and Rabbit Antibodies for the Bile Acid Isolithocholic Acid. Journal of Immunoassay and Immunochemistry 36:3, pages 233-252.
Read now
Alan F. Hofmann. (2004) Detoxification of Lithocholic Acid, A Toxic Bile Acid: Relevance to Drug Hepatotoxicity. Drug Metabolism Reviews 36:3-4, pages 703-722.
Read now

Articles from other publishers (14)

Yue Li, Qian Wang, Jingyi Jin, Bo Tan, Jie Ren, Guochao Song, Bin Zou, Fengyi Weng, Dongming Yan & Furong Qiu. (2023) 15,16-dihydrotanshinone I in Danshen ethanol extract aggravated cholestasis by inhibiting Cyp3a11 mediated bile acids hydroxylation. Toxicology Letters 377, pages 62-70.
Crossref
Shicheng Fan, Conghui Liu, Yiming Jiang, Yue Gao, Yixin Chen, Kaili Fu, Xinpeng Yao, Min Huang & Huichang Bi. (2019) Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation in mice. Journal of Ethnopharmacology 245, pages 112103.
Crossref
Kyunghee Yang, Cen Guo, Jeffrey L. Woodhead, Robert L. St. ClaireIIIIII, Paul B. Watkins, Scott Q. Siler, Brett A. Howell & Kim L.R. Brouwer. (2016) Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury. Journal of Pharmaceutical Sciences 105:2, pages 443-459.
Crossref
Eugene Hrycay, Dana Forrest, Lin Liu, Renxue Wang, Jenny Tai, Anand Deo, Victor Ling & Stelvio Bandiera. (2014) Hepatic bile acid metabolism and expression of cytochrome P450 and related enzymes are altered in Bsep −/− mice. Molecular and Cellular Biochemistry 389:1-2, pages 119-132.
Crossref
Masaaki Miyata, Masahiro Nomoto, Fumiaki Sotodate, Tomohiro Mizuki, Wataru Hori, Miho Nagayasu, Shinya Yokokawa, Shin-ichi Ninomiya & Yasushi Yamazoe. (2010) Possible protective role of pregnenolone-16α-carbonitrile in lithocholic acid-induced hepatotoxicity through enhanced hepatic lipogenesis. European Journal of Pharmacology 636:1-3, pages 145-154.
Crossref
Yazen Alnouti. (2009) Bile Acid Sulfation: A Pathway of Bile Acid Elimination and Detoxification. Toxicological Sciences 108:2, pages 225-246.
Crossref
Lisa D. Beilke, David G. Besselsen, Quiqiong Cheng, Supriya Kulkarni, Angela L. Slitt & Nathan J. Cherrington. (2008) Minimal Role of Hepatic Transporters in the Hepatoprotection against LCA-Induced Intrahepatic Cholestasis. Toxicological Sciences 102:1, pages 196-204.
Crossref
Masahiro Nomoto, Masaaki Miyata, Miki Shimada, Kouichi Yoshinari, Frank J Gonzalez, Shigeki Shibasaki, Tohru Kurosawa, Yasuhiro Shindo & Yasushi Yamazoe. (2007) ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output. European Journal of Pharmacology 574:2-3, pages 192-200.
Crossref
Hirotaka Kitada, Masaaki Miyata, Toshifumi Nakamura, Aki Tozawa, Wataru Honma, Miki Shimada, Kiyoshi Nagata, Christopher J. Sinal, Grace L. Guo, Frank J. Gonzalez & Yasushi Yamazoe. (2003) Protective Role of Hydroxysteroid Sulfotransferase in Lithocholic Acid-induced Liver Toxicity. Journal of Biological Chemistry 278:20, pages 17838-17844.
Crossref
Andréa M. A. Costa, Beatriz Tuchweber, Thierry Lamireau, Ibrahim M. Yousef, Charles Balabaud, Jean Rosenbaum & Alexis Desmoulière. (2003) Role of apoptosis in the remodeling of cholestatic liver injury following release of the mechanical stress. Virchows Archiv 442:4, pages 372-380.
Crossref
Renxue Wang, Myriam Salem, Ibrahim M. Yousef, Beatriz Tuchweber, Ping Lam, Sarah J. Childs, Cheryl D. Helgason, Cameron Ackerley, M. James Phillips & Victor Ling. (2001) Targeted inactivation of sister of P-glycoprotein gene ( spgp ) in mice results in nonprogressive but persistent intrahepatic cholestasis . Proceedings of the National Academy of Sciences 98:4, pages 2011-2016.
Crossref
Aldo Mottino, Beatriz Tuchweber, Gabriel L Plaa & Ibrahim M Yousef. (2000) Role of perivenous hepatocytes in taurolithocholate-induced cholestasis in vivo. Toxicology Letters 116:1-2, pages 69-77.
Crossref
S. A. Center. (1999) Chronic liver disease: current concepts of disease mechanisms. Journal of Small Animal Practice 40:3, pages 106-114.
Crossref
Piotr Milkiewicz, Charles O. Mills, Marcelo G. Roma, Jalal Ahmed-Choudhury, Elwyn Elias & Roger Coleman. (1999) Tauroursodeoxycholate and S-adenosyl-L-methionine exert an additive ameliorating effect on taurolithocholate-induced cholestasis: A study in isolated rat hepatocyte couplets. Hepatology 29:2, pages 471-476.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.