Advanced search
Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 9, 1985 - Issue 4
Submit an article Journal homepage
20
Views
42
CrossRef citations to date
0
Altmetric
Original Article

Hb Aztec or α762 Met → Thrβ2 Detection of a Silent Mutant by High Performance Liquid Chromatography

Joan B. Shelton Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena, CA, 91125
,
J. Roger Shelton Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena, CA, 91125
,
W. A. Schroeder Division of Chemistry and Chemical Engineering, California Institute of Technology Pasadena, CA, 91125
&
Darleen R. Powars Department of Pediatrics Division of Hematology/Oncology, University of Southern California School of Medicine Los Angeles, CA, 90033
Pages 325-332 | Received 11 Jan 1985, Accepted 26 Mar 1985, Published online: 07 Jul 2009

Citations (42)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (25)

Agathe Horri-Naceur & David J. Timson. (2020) In Silico Analysis of the Effects of Point Mutations on α-Globin: Implications for α-Thalassemia. Hemoglobin 44:2, pages 89-103.
Read now
R. Hojas-Bernal, P. McNab-Martin, V. F. Fairbanks, M. W. Holmes, J. D. Hoyer, D. J. McCormick & K. S. Kubik. (1999) Hb Chile [β28(B10)Leu→Met]: An unstable hemoglobin associated with chronic methemoglobinemia and sulfonamide or methylene blue-induced hemolytic anemia. Hemoglobin 23:2, pages 125-134.
Read now
T. Nakanishi, A. Miyazaki, M. Kishikawa, A. Shimizu, O. Kishida, S. Sumi, T. Tsubakio & K. Imai. (1998) A New Hemoglobin Variant Found During Hb A1c Measurement: Hb Hokusetsu [β52(D3)Asp→Gly]. Hemoglobin 22:4, pages 355-371.
Read now
D. Merritt, R. T. Jones, C. Head, S. N. Thibodeau, V. F. Fairbanks, M. H. Steinberg, M. B. Coleman & G. P. Rodgers. (1997) HB Seal Rock [(α2)142 Term→glu, Codon 142 TAA→GAA]: An Extended α Chain Variant Associated with Anemia, Microcytosis, and α-Thalassemia-2 (-3.7 KB). Hemoglobin 21:4, pages 331-344.
Read now
S. Rahbar, C. Lee, V. F. Fairbanks, D. J. McCormick, K. Kubik, B. J. Madden & G. Nozari. (1997) HB Watts [α74(EF3) OR α75(EF4)ASP→0]: A Shortened α Chain Variant Due to the Deletion of Three Nucleotides in Exon 2 of the α2-Globin Gene. Hemoglobin 21:4, pages 321-330.
Read now
M. F. H. Carver & T. H. J. Huisman. (1997) International Hemoglobin Information Center Variant List. Hemoglobin 21:6, pages 505-506.
Read now
A. Qualtieri, V. Andreoli, L. Crescibene, E. V. De Marco, M. Muglia, A. L. Gabriele, G. Annesi & C. Brancati. (1997) HB Valletta [β87(F3)THR →PRO] DUE to an A→C Substitution at Codon 87 in a Calabrian Family with α-Thalassemia. Hemoglobin 21:1, pages 97-103.
Read now
P. J. Hutt, V. F. Fairbanks, S. N. Thibodeau, M. M. Green, J. D. Hoyer, S. H. Block, C. Day, R. T. Jones & R. C. Barwick. (1997) Hb T-Cambodia, a β Chain Variant with the Mutations of Hb E and Hb D-Punjab, Confirmed by DNA Analysis. Hemoglobin 21:3, pages 205-218.
Read now
. (1996) Variants of the Alpha Chain. Hemoglobin 20:3, pages 215-312.
Read now
. (1994) International Hemoglobin Information Center. Hemoglobin 18:2, pages 77-161.
Read now
K. Krishnan, F. Martinez, R. T. Wille, R. T. Jones, D. T. Shin, C. Head, V. F. Fairbanks & L. Dabich. (1994) HB Washtenaw [βT11(A8)VAL-PHE]: An Electrophoretically Silent, Unstable, Low Oxygen Affinity Variant Associated with Anemia and Chronic Cyanosis. Hemoglobin 18:4-5, pages 285-295.
Read now
. (1993) Variants of the Alpea Chain. Hemoglobin 17:2, pages 89-177.
Read now
. (1992) Variants of the Alpha Chain. Hemoglobin 16:3, pages 127-213.
Read now
E. V. De Marco, L. Crescibene, A. Pasqua, C. Brancati, M. Bria & A. Qualtieri. (1992) Hb Prato α31(B12)Arg→ser] in a Calabrian Family. Hemoglobin 16:4, pages 275-279.
Read now
Robin P. Steffek & Michael J. Thomas. (1991) Hydrogen Peroxide Modification of Human Oxyhemoglobin. Free Radical Research Communications 13:1, pages 489-497.
Read now
. (1991) International hemoglobin information center: Variants of the alpha chain. Hemoglobin 15:3, pages 139-217.
Read now
R. T. Jones, H. I. Saiontz, C. Head, D. T. B. Shin & V. F. Fairbanks. (1990) A New Electrophoretically Silent Variant That Causes Erythrocytosis. Hemoglobin 14:2, pages 147-156.
Read now
. (1990) International Hemoglobin Information Center. Hemoglobin 14:3, pages 249-325.
Read now
L. Kéclard, A. Campier, G. Mérault, A. Aupérin, J. Riou, J. Rosa & F. Galactéros. (1990) Hemoglobin Nevers [αβ2 130(H8)TYR↣R]; A New Silent Variant Found in France. Hemoglobin 14:1, pages 103-107.
Read now
. (1989) Variants of the Alpha Chain. Hemoglobin 13:3, pages 223-297.
Read now
. (1988) IHIC Variants List. Hemoglobin 12:3, pages 209-282.
Read now
C. Lacombe, Y. Blouquit, N. Arous, J. Riou, J. L. Harousseau, J. Bardakdjian, N. Milpied & F. Galacteros. (1987) Hb Potomac [β101(G3)Glu→Asp] in a Polish Family Living in France. Hemoglobin 11:1, pages 55-59.
Read now
C. Lacombe, J. Soria, N. Arous, Y. Blouquit, J. Barda Kdjian, J. Riou & F. Galacteros. (1987) A New Case of Hb Dagestan [α60(E9)Lys→Glu]. Hemoglobin 11:1, pages 39-41.
Read now
. (1987) IHIC Variants List. Hemoglobin 11:3, pages 243-308.
Read now
. (1986) International Hemoglobin Information Center IHIC Variants List. Hemoglobin 10:3, pages 261-327.
Read now

Articles from other publishers (17)

Amer Alagic, Agnieszka Koprianiuk & Ronald Kluger. (2005) Hemoglobin−Superoxide DismutaseChemical Linkages That Create a Dual-Function Protein. Journal of the American Chemical Society 127:22, pages 8036-8043.
Crossref
G. Elizabeth Elder, Terry R.J. Lappin, Allen B. Horne, Virgil F. Fairbanks, Richard T. Jones, Paul C. Winter, Brian N. Green, James D. Hoyer, Timothy M. Reynolds, Daniel T.-B. Shih, Daniel J. McCormick, Kathleen S. Kubik, Benjamin J. Madden, Charlotte G. Head, D. Harvey & Norman B. Roberts. (1998) Hemoglobin Old Dominion/Burton-upon-Trent, β143 (H21) His→Tyr, Codon 143 CAC→TAC—a Variant With Altered Oxygen Affinity That Compromises Measurement of Glycated Hemoglobin in Diabetes Mellitus: Structure, Function, and DNA Sequence. Mayo Clinic Proceedings 73:4, pages 321-328.
Crossref
Amy E. Ferry, Surendra B. Baliga, Carlos Monteiro & Betty S. Pace. (1997) Globin Gene Silencing in Primary Erythroid Cultures. Journal of Biological Chemistry 272:32, pages 20030-20037.
Crossref
V. B. Rao, P. G. Natrajan, C. P. Lulla & S. B. Bandodkar. (1997) Rapid Mid-Trimester Prenatal Diagnosis of Beta-thalassaemia and other Haemoglobinopathies using a Non-Radioactive Anion Exchange HPLC Technique—An Indian Experience. Prenatal Diagnosis 17:8, pages 725-731.
Crossref
P. Jesse Hutt, Milton H. Donaldson, Jamil Khatri, Virgil F. Fairbanks, James D. Hoyer, Stephen N. Thibodeau, Michael S. Moxness, Lydia E. McMorrow, Michael M. Green & Richard T. Jones. (1996) Hemoglobin S/hemoglobin Osler: A case with 3 β globin chains. DNA sequence (AAT) proves that Hb Osler is β 145 Tyr→Asn. American Journal of Hematology 52:4, pages 305-309.
Crossref
SALLY P. STABLER, RICHARD T. JONES, CHARLOTTE HEAD, DANIEL T.-B. SHIH & VIRGIL F. FAIRBANKS. (1994) Hemoglobin Denver [α2β241 (C7) Phe→Ser]: A Low-O2-Affinity Variant Associated With Chronic Cyanosis and Anemia. Mayo Clinic Proceedings 69:3, pages 237-243.
Crossref
Richard T. Jones. 1994. Hemoglobins Part B: Biochemical and Analytical Methods. Hemoglobins Part B: Biochemical and Analytical Methods 322 343 .
Myron D. Gross, Susan M. Gapstur, John D. Belcher, Gale Scanlan & John D. Potter. (2006) The Identification and Partial Characterization of Acetaldehyde Adducts of Hemoglobin Occurring in Vivo: A Possible Marker of Alcohol Consumption. Alcoholism: Clinical and Experimental Research 16:6, pages 1093-1103.
Crossref
D A Tagle, J L Slightom, R T Jones & M Goodman. (1991) Concerted evolution led to high expression of a prosimian primate delta globin gene locus.. Journal of Biological Chemistry 266:12, pages 7469-7480.
Crossref
MICHAEL C. PERRY, CHARLOTTE HEAD, VIRGIL F. FAIRBANKS, RICHARD T. JONES, HENRY TAYLOR & VIRGINIA PROUD. (1991) Hemoglobin Columbia Missouri or α2[88 (F9) Ala→Val]β2: A New High-Oxygen-Affinity Hemoglobin That Causes Erythrocytosis. Mayo Clinic Proceedings 66:1, pages 5-10.
Crossref
Lawrence K. Duffy & Rebecca A. Reynolds. (1990) High-performance liquid chromatographic separation and partial characterization of the α- and β-chains of Alaskan sockeye salmon hemoglobin. Journal of Chromatography A 512, pages 291-297.
Crossref
VIRGIL F. FAIRBANKS, RICHARD T. JONES, CHARLOTTE HEAD, STEVEN R. VOGEL, RHAIZA OLIVEROS, BERNADINE BRIMHALL, MURRAY N. SILVERSTEIN & RAINIS BERZINS. (1990) Two Families With Hemoglobin Sogn, β(A11)14 Leu→Arg, in Minnesota and Indiana: Hematologic, Functional, and Biosynthetic Features. Mayo Clinic Proceedings 65:6, pages 793-798.
Crossref
G Amiconi, F Ascoli, D Barra, A Bertollini, R M Matarese, D Verzili & M Brunori. (1989) Selective Oxidation of Methionine β(55)D6 at the α1β1 Interface in Hemoglobin Completely Destabilizes the T-state. Journal of Biological Chemistry 264:30, pages 17745-17749.
Crossref
M P Kavanaugh, M F Perutz, G Fermi, D T Shih & R T Jones. (1989) Structure and Function of Human Hemoglobin Covalently Labeled with Periodate-oxidized Adenosine Triphosphate. Journal of Biological Chemistry 264:19, pages 11009-11013.
Crossref
Danilo A. Tagle, Ben F. Koop, Morris Goodman, Jerry L. Slightom, David L. Hess & Richard T. Jones. (1988) Embryonic ε and γ globin genes of a prosimian primate (Galago crassicaudatus). Journal of Molecular Biology 203:2, pages 439-455.
Crossref
Alan S. Keitt & Richard T. Jones. (2006) The variant fetal hemoglobin F Texas I is abnormally acetylated. American Journal of Hematology 28:1, pages 47-52.
Crossref
Michael P. Kavanaugh, Daniel T. B. Shih & Richard T. Jones. (2002) Affinity labeling of hemoglobin with 4,4'-diisothiocyanostilbene-2,2'-disulfonate: covalent cross-linking in the 2,3-diphosphoglycerate binding site. Biochemistry 27:5, pages 1804-1808.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.