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Hemoglobin
international journal for hemoglobin research
Volume 35, 2011 - Issue 3
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PROCEEDINGS 19th ICOC November 2009, London, UK

Sequential Alternating Deferiprone And Deferoxamine Treatment Compared To Deferiprone Monotherapy: Main Findings And Clinical Follow-Up Of A Large Multicenter Randomized Clinical Trial In -Thalassemia Major Patients

Gaetano Restivo PantaloneUnità Operativa Complessa Ematologia II con Talassemia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia, Vincenzo Cervello, Palermo, ItaliaCorrespondence[email protected]
,
Aurelio MaggioUnità Operativa Complessa Ematologia II con Talassemia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia, Vincenzo Cervello, Palermo, Italia
,
Angela VitranoUnità Operativa Complessa Ematologia II con Talassemia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia, Vincenzo Cervello, Palermo, Italia
,
Marcello CapraUnità Operativa Complessa VII Pediatria per le Emopatie Ereditarie, Centro di Prevenzione Diagnosi e Cura della Talassemia, Azienda Ospedaliera Giuseppe Di Cristina, Palermo, Italia
,
Liana CucciaUnità Operativa Complessa VII Pediatria per le Emopatie Ereditarie, Centro di Prevenzione Diagnosi e Cura della Talassemia, Azienda Ospedaliera Giuseppe Di Cristina, Palermo, Italia
,
Francesco GagliardottoUnità Operativa Complessa VII Pediatria per le Emopatie Ereditarie, Centro di Prevenzione Diagnosi e Cura della Talassemia, Azienda Ospedaliera Giuseppe Di Cristina, Palermo, Italia
,
Aldo FilosaUnità Operativa Complessa Pediatria, Azienda Ospedaliera Cardarelli, Napoli, Italia
,
Maria Antonietta RomeoUnità Operativa Complessa Talassemia, Clinica Pediatrica I Università degli Studi di Catania, Azienda Ospedaliera Policlinico, Catania, Italia
,
Carmelo MagnanoUnità Operativa Dipartimentale Talassemia, Presidio Ospedaliera San Luigi-Currò, Azienda Ospedaliera Garibaldi, Catania, Italia
,
Vincenzo CarusoUnità Operativa Dipartimentale Talassemia, Presidio Ospedaliera San Luigi-Currò, Azienda Ospedaliera Garibaldi, Catania, Italia
,
Crocetta ArgentoUnità Operativa Complessa Medicina Trasfusionale, Azienda Ospedaliera San Giovanni di Dio, Agrigento, Italia
,
Calogera GerardiUnità Operativa Semplice di Talassemia, Presidio Ospedaliero Giovanni Pauloo II, Sciacca, Italia
,
Saveria CampisiUnità Operativa Semplice Centro Microcitemia, Azienda Ospedaliera Umberto I, Siracusa, Italia
,
Pietro VioliCasa Sollievo della Sofferenza, Istituto di Ricovero e Cura a Carattere Scientifico, Unità Operativa Centro della Microcitemia, San Giovanni Rotondo, Foggia, Italia
,
Roberto MaliziaUnità Operativa Complessa Pediatria II, Azienda Ospedaliera Ospedali Riuniti Villa Sofia, Vincenzo Cervello, Palermo, Italia
,
Paolo CianciulliUnità Operativa Talassemia, Azienda Ospedaliera San Eugenio, Roma, Italia
,
Michele RizzoUnità Operativa Complessa Ematologia, Azienda Ospedaliera San Elia, Caltanissetta, Italia
,
Domenico Giuseppe D’AscolaCentro Microcitemia, Azienda Ospedaliera Bianchi Melacrino Morelli, Reggio Calabria, Italia
,
Alessandra QuotaUnità Operativa Complessa Medicina Trasfusionale Azienda Ospedaliera Vittorio Emanuele III, Gela, Italia
,
Luciano ProssomaritiCentro Regionale per la Cura delle Microcitemie, Azienda Ospedaliera Cardarelli, Napoli, Italia
,
Carmelo FidoneUnità Operativa Complessa Centro Trasfusionale, Azienda Ospedaliera Maria Paternò Arezzo, Ragusa, Italia
,
Paolo RiganoUnità Operativa Complessa Ematologia II con Talassemia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia, Vincenzo Cervello, Palermo, Italia
,
Alessia PepeIstituto di Fisiologia Clinica Consiglio Nazionale delle Ricerche, Pisa, Italia
,
Gennaro D’AmicoUnità Operativa Complessa Gastroenterologia, Azienda Ospedaliera Ospedali Riuniti Villa Sofia, Vincezo Cervello, Palermo, Italia
,
Alberto MorabitoIstituto Giulio Alfredo Maccacaro, Università di Milano, Milano, Italia
&
Christian GluudCopenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
 show all
Pages 206-216 | Published online: 20 May 2011

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Richa Shah, Aashaka Shah & Sherif M. Badawy. (2023) An evaluation of deferiprone as twice-a-day tablets or in combination therapy for the treatment of transfusional iron overload in thalassemia syndromes. Expert Review of Hematology 16:2, pages 81-94.
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Adriana Ceci, Rosa Conte, Antonella Didio, Donato Bonifazi, Mariagrazia Felisi, Viviana Giannuzzi & Fedele Bonifazi. (2019) An overview of the efficacy and safety of deferiprone in paediatric patients with congenital haemoglobinopathies and chronic iron overload. Expert Opinion on Orphan Drugs 7:4, pages 181-197.
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Kevin H.M. Kuo & Marko Mrkobrada. (2014) A Systematic Review and Meta-Analysis of Deferiprone Monotherapy and in Combination with Deferoxamine for Reduction of Iron Overload in Chronically Transfused Patients with β-Thalassemia. Hemoglobin 38:6, pages 409-421.
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Articles from other publishers (15)

Louise J Geneen, Carolyn Dorée & Lise J Estcourt. (2023) Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia. Cochrane Database of Systematic Reviews 2023:3.
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Christine C. Hsu, Nizar H. Senussi, Kleber Y. Fertrin & Kris V. Kowdley. (2022) Iron overload disorders. Hepatology Communications 6:8, pages 1842-1854.
Crossref
Andrew Binding, Richard Ward, George Tomlinson & Kevin H. M. Kuo. (2019) Deferiprone exerts a dose‐dependent reduction of liver iron in adults with iron overload. European Journal of Haematology 103:2, pages 80-87.
Crossref
Nancy F. Olivieri, Amir Sabouhanian & Brenda L. Gallie. (2019) Single-center retrospective study of the effectiveness and toxicity of the oral iron chelating drugs deferiprone and deferasirox. PLOS ONE 14:2, pages e0211942.
Crossref
Patricia M Fortin, Sheila A Fisher, Karen V Madgwick, Marialena Trivella, Sally Hopewell, Carolyn Doree & Lise J Estcourt. (2018) Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia. Cochrane Database of Systematic Reviews 2018:5.
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Robert Crichton. 2016. Iron Metabolism. Iron Metabolism 376 417 .
Somayeh Kalanaky, Maryam Hafizi, Sepideh Safari, Kazem Mousavizadeh, Mahboubeh Kabiri, Alireza Farsinejad, Saideh Fakharzadeh & Mohammad Hassan Nazaran. (2016) TLc-A, the leading nanochelating-based nanochelator, reduces iron overload in vitro and in vivo. International Journal of Hematology 103:3, pages 274-282.
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Raffaella Origa. (2014) Combination Therapies in Iron Chelation. Thalassemia Reports 4:3, pages 4862.
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Maria Marsella & Caterina Borgna-Pignatti. (2014) Transfusional Iron Overload and Iron Chelation Therapy in Thalassemia Major and Sickle Cell Disease. Hematology/Oncology Clinics of North America 28:4, pages 703-727.
Crossref
Vip Viprakasit & Worapant Kriengsoontornkij. 2014. A worldwide yearly survey of new data in adverse drug reactions and interactions. A worldwide yearly survey of new data in adverse drug reactions and interactions 419 433 .
Sujian Xia, Weidong Zhang, Liting Huang & Hong Jiang. (2013) Comparative Efficacy and Safety of Deferoxamine, Deferiprone and Deferasirox on Severe Thalassemia: A Meta-Analysis of 16 Randomized Controlled Trials. PLoS ONE 8:12, pages e82662.
Crossref
Sheila A Fisher, Susan J Brunskill, Carolyn Doree, Onima Chowdhury, Sarah Gooding & David J Roberts. (2013) Oral deferiprone for iron chelation in people with thalassaemia. Cochrane Database of Systematic Reviews.
Crossref
Sheila A Fisher, Susan J Brunskill, Carolyn Doree, Sarah Gooding, Onima Chowdhury & David J Roberts. (2013) Desferrioxamine mesylate for managing transfusional iron overload in people with transfusion-dependent thalassaemia. Cochrane Database of Systematic Reviews.
Crossref
Dennis J. Cada, Terri L. Levien & Danial E. Baker. (2012) Deferiprone. Hospital Pharmacy 47:2, pages 129-136.
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V. S. Nadarajan. (2011) Modern management of thalassemia. ISBT Science Series 6:2, pages 432-437.
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