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Hemoglobin
international journal for hemoglobin research
Volume 36, 2012 - Issue 4
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Original Article

The XmnI and BCL11A Single Nucleotide Polymorphisms May Help Predict Hydroxyurea Response in Iranian β-Thalassemia Patients

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Pages 371-380 | Received 28 Dec 2011, Accepted 24 Feb 2012, Published online: 11 Jun 2012

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Read on this site (9)

Alexandra Kolliopoulou, Stavroula Siamoglou, Anne John, Argyro Sgourou, Alexandra Kourakli, Argiris Symeonidis, Efthymia Vlachaki, Panagiota Chalkia, Stamatia Theodoridou, Bassam R. Ali, Theodora Katsila, George P. Patrinos & Adamantia Papachatzopoulou. (2019) Role of Genomic Biomarkers in Increasing Fetal Hemoglobin Levels Upon Hydroxyurea Therapy and in β-Thalassemia Intermedia: A Validation Cohort Study. Hemoglobin 43:1, pages 27-33.
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Florinda Listì, Serena Sclafani, Veronica Agrigento, Rita Barone, Aurelio Maggio & Elena D’Alcamo. (2018) Study on the Role of Polymorphisms of the SOX-6 and MYB Genes and Fetal Hemoglobin Levels in Sicilian Patients with β-Thalassemia and Sickle Cell Disease. Hemoglobin 42:2, pages 103-107.
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Joanne Traeger-Synodinos & Cornelis L. Harteveld. (2017) Preconception carrier screening and prenatal diagnosis in thalassemia and hemoglobinopathies: challenges and future perspectives. Expert Review of Molecular Diagnostics 17:3, pages 281-291.
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Mehran Karimi, Parisa Jooya, Sezaneh Haghpanah, Maral Mokhtari, Narges Rezaei, Maede Fath & Shirin Parand. (2016) Evaluation of the Relationship Between Hb F Levels and Nucleated Red Blood Cells with Morbidity in Non Transfusion-Dependent Thalassemia Patients. Hemoglobin 40:4, pages 250-256.
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Alessia Finotti, Monica Borgatti, Nicoletta Bianchi, Cristina Zuccato, Ilaria Lampronti & Roberto Gambari. (2016) Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations. Expert Opinion on Orphan Drugs 4:3, pages 299-315.
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Giulia Breveglieri, Alessia Finotti, Monica Borgatti & Roberto Gambari. (2015) Recent patents and technology transfer for molecular diagnosis of β-thalassemia and other hemoglobinopathies. Expert Opinion on Therapeutic Patents 25:12, pages 1453-1476.
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Raffaella Origa, Alessandro Baldan, Maria Marsella & Caterina Borgna-Pignatti. (2015) A complicated disease: what can be done to manage thalassemia major more effectively?. Expert Review of Hematology 8:6, pages 851-862.
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Mehrnoush Kosaryan, Mandana Zafari, Abbass Alipur & Akbar Hedayatizadeh-Omran. (2014) The Effect and Side Effect of Hydroxyurea Therapy on Patients With β-Thalassemia: A Systematic Review to December 2012. Hemoglobin 38:4, pages 262-271.
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Mehdi Banan, Hadi Bayat, Pegah Namdar-Aligoodarzi, Azita Azarkeivan, Koorosh Kamali, Parvaneh Daneshmand, Behzad Zaker-Kandjani & Hossein Najmabadi. (2013) Utility Of The Multivariate Approach In Predicting β-Thalassemia Intermedia Or β-Thalassemia Major Types In Iranian Patients. Hemoglobin 37:5, pages 413-422.
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Urmimala Bhattacharjee, Alka Khadwal, Nusrat Shafiq, Deepesh Lad, Prashant Sharma, Reena Das, Prateek Shukla, Arihant Jain, Gaurav Prakash & Pankaj Malhotra. (2023) A Phase 2 Randomized Controlled Trial of Single-Agent Hydroxyurea Versus Thalidomide Among Adult Transfusion Dependent β Thalassemia Patients. Indian Journal of Hematology and Blood Transfusion.
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Kongtana Trakarnsanga, Nontaphat Thongsin, Chanatip Metheetrairut, Chartsiam Tipgomut, Saiphon Poldee & Methichit Wattanapanitch. (2022) Genetic correction of haemoglobin E in an immortalised haemoglobin E/beta-thalassaemia cell line using the CRISPR/Cas9 system. Scientific Reports 12:1.
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Saqib H. Ansari, Zeeshan Hussain, Muhammad Zohaib, Sadia Parveen, Bushra Kaleem, Hina Qamar, Omair Adil, Muhammad T. Khan & Tahir S. Shamsi. (2022) A Pragmatic Scoring Tool to Predict Hydroxyurea Response Among β-Thalassemia Major Patients in Pakistan. Journal of Pediatric Hematology/Oncology 44:1, pages e77-e83.
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Mehran Karimi, Tahereh Zarei, Ardeshir Bahmanimehr, Azam Aramesh, Saeed Daryanoush & Sezaneh Haghpanah. (2021) Long-term safety and efficacy of hydroxyurea in patients with non-transfusion-dependent β-thalassemia: a comprehensive single-center experience. Annals of Hematology 100:12, pages 2901-2907.
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Ali Dehshahri, Alessio Biagioni, Hadi Bayat, E. Hui Clarissa Lee, Mohammad Hashemabadi, Hojjat Samareh Fekri, Ali Zarrabi, Reza Mohammadinejad & Alan Prem Kumar. (2021) Editing SOX Genes by CRISPR-Cas: Current Insights and Future Perspectives. International Journal of Molecular Sciences 22:21, pages 11321.
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Kariofyllis Karamperis, Maria T. Tsoumpeli, Fotios Kounelis, Maria Koromina, Christina Mitropoulou, Catia Moutinho & George P. Patrinos. (2021) Genome-based therapeutic interventions for β-type hemoglobinopathies. Human Genomics 15:1.
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Kun Yang, Yi Wu, Yanni Ma, Jian Xiao, Yali Zhou & Xiaolin Yin. (2020) The association of HBG2, BCL11A, and HBS1L-MYB polymorphisms to thalidomide response in Chinese β-thalassemia patients. Blood Cells, Molecules, and Diseases 84, pages 102442.
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Sarah T. Diepstraten & Adam H. Hart. (2019) Modelling human haemoglobin switching. Blood Reviews 33, pages 11-23.
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Nahal Maroofi, Azita Azarkeivan, Soosan Banihashemi, Saeid Mohammadparast, Ali Aghajanirefah & Mehdi Banan. (2017) An enhancer haplotype may influence BCL11A expression levels and the response to hydroxyurea in β-thalassemia patients . Pharmacogenomics 18:10, pages 995-967.
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Serena Sclafani, Alice Pecoraro, Veronica Agrigento, Antonio Troia, Rosario Di Maggio, Massimiliano Sacco, Aurelio Maggio, Elena D'Alcamo & Rosalba Di Marzo. (2016) Study on Hydroxyurea Response in Hemoglobinopathies Patients Using Genetic Markers and Liquid Erythroid Cultures. Hematology Reports 8:4, pages 56-60.
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Lantip Rujito, Muhammad Basalamah, Wahyu Siswandari, Joko Setyono, Gondo Wulandari, Sri Mulatsih, Abdul Salam M. Sofro, Ahmad Hamim Sadewa & Sutaryo Sutaryo. (2016) Modifying effect of XmnI, BCL11A, and HBS1L-MYB on clinical appearances: A study on β-thalassemia and hemoglobin E/β-thalassemia patients in Indonesia. Hematology/Oncology and Stem Cell Therapy 9:2, pages 55-63.
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Khaled M. MusallamAli T. TaherMaria Domenica CappelliniVijay G. Sankaran. (2013) Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia. Blood 121:12, pages 2199-2212.
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Mehdi Banan. (2013) Hydroxyurea treatment in β-thalassemia patients: to respond or not to respond?. Annals of Hematology 92:3, pages 289-299.
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