Advanced search
Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 38, 2014 - Issue 3
Submit an article Journal homepage
279
Views
11
CrossRef citations to date
0
Altmetric
Research Article

A Study of δ-Globin Gene Mutations in the UK Population: Identification of Three Novel Variants and Development of a Novel DNA Test for Hb A′2

Mohamed S. M. KhalilDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUK
,
Samy MaroufDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUK
,
David ElementDepartment of Haematology, St. George’s Hospital LondonUK
,
Adele TimbsDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUK
,
Alice GallienneDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUK
,
Anna SchuhDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUK
,
John M. OldDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUKCorrespondence[email protected] [email protected]
&
Shirley HendersonDepartment of Haematology, National Haemoglobinopathy Reference Laboratory, Oxford Molecular Diagnostic Centre, John Radcliffe Hospital Oxford, OxfordshireUK
 show all
Pages 201-206 | Received 20 Jul 2013, Accepted 25 Oct 2013, Published online: 06 Mar 2014

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Ida Stangerup, Jesper Petersen & Andreas Glenthøj. (2021) Hb A2-Calderdale [δ2(NA2)His→Asn; HBD: c.7C>A] and Misdiagnosis of Type 2 Diabetes Mellitus Due to Interference with Hb A1c When Using Cation Exchange High Performance Liquid Chromatography: A Case Report. Hemoglobin 45:3, pages 207-209.
Read now
Lina Guo, Anika Kausar, John M. Old, Shirley J. Henderson & Alice E. Gallienne. (2015) Characterization of Hb Lepore Variants in the UK Population. Hemoglobin 39:1, pages 58-61.
Read now

Articles from other publishers (9)

Chulikon Hanart, Kritsada Singha, Yotsombat Changtrakul, Supan Fucharoen & Hataichanok Srivorakun. (2023) Prospective screening for δ-hemoglobinopathies associated with decreased hemoglobin A2 levels or hemoglobin A2 variants: A single center experience. Clinica Chimica Acta 547, pages 117417.
Crossref
Amphai Phasit, Sitthichai Panyasai, Monthon Mayoon, Niphawan Jettawan & Surada Satthakarn. (2022) Phenotypic Expression of Known and Novel Hemoglobin A2-Variants, Hemoglobin A2-Mae Phrik [Delta 52(D3) Asp > Gly, HBD:c.158A > G], Associated with Hemoglobin E [Beta 26(B8) Glu > Lys, HBB:c.79G > A] in Thailand. Genes 13:6, pages 959.
Crossref
Noraesah Mahmud, Massimo Maffei, Massimo Mogni, Gian Luca Forni, Valeria Maria Pinto, Giuseppina Barberio, Silvana Ungari, Antonella Maffè, Cristina Curcio, Francesco Zanolli, Raffaella Paventa, Mariarosa Carta, Alberta Caleffi, Mariella Mercadanti, Sauro Maoggi, Giovanni Ivaldi & Domenico Coviello. (2021) Hemoglobin A2 and Heterogeneous Diagnostic Relevance Observed in Eight New Variants of the Delta Globin Gene. Genes 12:11, pages 1821.
Crossref
Kritsada Singha, Goonnapa Fucharoen & Supan Fucharoen. (2021) δ-Hemoglobinopathies in Thailand: screening, molecular basis, genotype-phenotype interaction, and implication for prevention and control of thalassemia. Annals of Hematology 100:8, pages 1953-1963.
Crossref
Thanet Prajantasen, Patcharawadee Prayalaw, Sitthichai PanyasaiSukanya Binlee & Supang Nongnuan. (2021) Development of a High Resolution Melting Curve Analysis for the Detection of Hemoglobin δ-Chain Variants in Thailand and Identification of Hb A2-Walsgrave [codon 52 (GAT>CAT), Asp→His; HBD:c.157G>C] in a Pregnant Woman from Southern Thailand. Genetic Testing and Molecular Biomarkers 25:6, pages 426-433.
Crossref
Jie Zhang, Yang Yang, Peng Li, Yuanlong Yan, Tao Lv, Tingting Zhao, Xiaohong Zeng, Dongmei Li, Xiaoyan Zhou, Hong Chen, Jie Su, Tonghua Yang, Jing He & Baosheng Zhu. (2019) Analysis of deletional hereditary persistence of fetal hemoglobin/δβ‐thalassemia and δ‐globin gene mutations in Southerwestern China. Molecular Genetics & Genomic Medicine 7:6.
Crossref
Anita H. Nadkarni, Ajit C. Gorakshakar, Pratibha M. Sawant, Khushnooma Y. Italia, Dipti S. Upadhye, Manju S. Gorivale, Pallavi R. Mehta, Priya Hariharan, Kanjaksha Ghosh & Roshan B. Colah. (2018) The phenotypic and molecular diversity of hemoglobinopathies in India: A review of 15 years at a referral center. International Journal of Laboratory Hematology 41:2, pages 218-226.
Crossref
Ana Villegas, Fernando Ataúlfo González, Jorge M Nieto, Félix de la Fuente-Gonzalo, Rafael Martínez, María Josefa Torrejón & Paloma Ropero. (2017) Haemoglobinopathies that occur with decreased HbA 2 levels: a gene mutation set involving the δ gene at a Spanish centre . Journal of Clinical Pathology 70:1, pages 75-80.
Crossref
P. Hariharan, S. Colaco, R. Colah, K. Ghosh & A. Nadkarni. (2016) Delta globin gene variations leading to reduction in HbA 2 levels . International Journal of Laboratory Hematology 38:6, pages 610-615.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.