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Hemoglobin
international journal for hemoglobin research
Volume 15, 1991 - Issue 6
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Original Article

The Origin of the Sickle Mutation in Greece; Evidence from βS Globin Gene Cluster Polymorphisms

M. Boussiou Unit for Prenatal Diagnosis, Laikon Hospital, 115 27, Athens, Greece
,
D. Loukopoulos First Department of Medicine, University of Athens Laikon Hospital, 115 27, Athens, Greece
,
J. Christakis First Department of Medicine, University of Thessaloniki “AHEPA” Hospital, Thessaloniki, Greece
&
Ph. Fessas First Department of Medicine, University of Athens Laikon Hospital, 115 27, Athens, Greece
Pages 459-467 | Received 16 Apr 1997, Published online: 07 Jul 2009

Citations (16)

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Fekri Samarah, Suhail Ayesh, Miranda Athanasiou, John Christakis & Norma Vavatsi. (2009) βS-Globin Gene Cluster Haplotypes in the West Bank of Palestine. Hemoglobin 33:2, pages 143-149.
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Andreani R. Kyrri, Xenia Felekis, Eleni Kalogerou, Barbara J. Wild, Loukas Kythreotis, Marios Phylactides & Marina Kleanthous. (2009) Hemoglobin Variants in Cyprus. Hemoglobin 33:2, pages 81-94.
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G. Lacerra, G. Fioretti, A. Hani, D. Duka, M. De Angioletti, L. Pagano, A. Viola, S. Desicato, P. Ferranti, P. Pucci, E. Boletini & C. Carestia. (1993) HB O-Arab [β121(GH4)GLU→LYS]: Association with DNA Polymorphisms of African Ancestry in two Mediterranean Families. Hemoglobin 17:6, pages 523-535.
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Articles from other publishers (13)

Imen Moumni, Maha Ben Mustapha, Sarra Sassi, Amine Zorai, Ikbel Ben Mansour, Kais Douzi, Dorra Chouachi, Fethi Mellouli, Mohamed Bejaoui & Salem Abbes. (2014) Haplotype Map of Sickle Cell Anemia in Tunisia. Disease Markers 2014, pages 1-7.
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Bridget S. Penman, Sunetra Gupta & Caroline O. Buckee. (2012) The emergence and maintenance of sickle cell hotspots in the Mediterranean. Infection, Genetics and Evolution 12:7, pages 1543-1550.
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Moumni Imen, Ben Mansour Mosbehi Ikbel, Chaouch Leila, Mellouli Fethi, Zorai Amine, Bejaoui Mohamed & Abbes Salem. (2011) Restriction mapping of βS locus among tunisian sickle-cell patients. American Journal of Human Biology 23:6, pages 815-819.
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Bridget S. Penman, Oliver G. Pybus, David J. Weatherall & Sunetra Gupta. (2009) Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean. Proceedings of the National Academy of Sciences 106:50, pages 21242-21246.
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George P. Patrinos, Piera Samperi, Luca lo Nigro, Panagoula Kollia, Gino Schiliro & Manoussos N. Papadakis. (2005) Evidence for the molecular heterogeneity of sickle cell anemia chromosomes bearing the β S /Benin haplotype . American Journal of Hematology 80:1, pages 79-80.
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Ronald L. Nagel. (2005) Epistasis and the genetics of human diseases. Comptes Rendus Biologies 328:7, pages 606-615.
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Spyros P Dourakis, Alexandra Alexopoulou, Constantin Papageorgiou, Andreas Kaloterakis & Stephanos J Hadziyannis. (2004) Acute chest syndrome in sickle-cell trait. European Journal of Internal Medicine 15:4, pages 248-250.
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Vassiliki Kalotychou, Panagoula Kollia, Ersi Voskaridou, Theoharis Patargias, Nicholas P. Anagnou & Dimitris Loukopoulos. (2002) Functional Role of the Four Different Types of (AT)XTY Motifs 5′ to the β-Globin Gene and Their Distribution in the Greek Population. Blood Cells, Molecules, and Diseases 28:1, pages 39-46.
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David P. Steensma, James D. Hoyer & Virgil F. Fairbanks. (2001) Hereditary Red Blood Cell Disorders in Middle Eastern Patients. Mayo Clinic Proceedings 76:3, pages 285-293.
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Dimitris Loukopoulos, Ersi Voskaridou, Vassiliki Kalotychou, Maria Schina, Aphrodite Loutradi & Ilias Theodoropoulos. (2000) Reduction of the Clinical Severity of Sickle Cell/β-Thalassemia with Hydroxyurea: The Experience of a Single Center in Greece. Blood Cells, Molecules, and Diseases 26:5, pages 453-466.
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George P. Patrinos, Aphrodite Loutradi-Anagnostou & Manoussos N. Papadakis. (1996) A new base substitution in the 5′ regulatory region of the humanAγ globin gene is linked with the βs gene. Human Genetics 97:3, pages 357-358.
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Ersi Voskaridou, Vassiliki Kalotychou & Dimitris Loukopoulos. (2008) Clinical and laboratory effects of long‐term administration of hydroxyurea to patients with sickle‐cell/β‐thalassaemia. British Journal of Haematology 89:3, pages 479-484.
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Graham R. Serjeant. (1994) The Geography of Sickle Cell Disease: Opportunities for Understanding its Diversity. Annals of Saudi Medicine 14:3, pages 237-246.
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