499
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Use of crospovidone as pelletization aid as alternative to microcrystalline cellulose: effects on pellet properties

, &
Pages 1325-1332 | Received 07 Oct 2008, Accepted 17 Mar 2009, Published online: 16 Oct 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Udit Arora, Vaishali Thakkar, Lalji Baldaniya & Mukesh C. Gohel. (2020) Fabrication and evaluation of fast disintegrating pellets of cilostazol. Drug Development and Industrial Pharmacy 46:12, pages 1927-1946.
Read now
Hadi Afrasiabi Garekani, Seyede Fatemeh Aftabi, Fatemeh Fahimi Nia, Mohammad Javidi, Ali Nokhodchi & Fatemeh Sadeghi. (2019) Synergistic effect of polyethylene glycol and superdisintegrant on dissolution rate enhancement of simvastatin in pellet formulation. Pharmaceutical Development and Technology 24:6, pages 720-728.
Read now
Nikhil C. Loka, Kalyan K. Saripella, Colin A. Pinto & Steven H. Neau. (2018) Use of extrusion aids for successful production of Kollidon® CL-SF pellets by extrusion–spheronization. Drug Development and Industrial Pharmacy 44:4, pages 632-642.
Read now
Matteo Cerea, Franco Pattarino, Andrea Foglio Bonda, Luca Palugan, Lorena Segale & Carlo Vecchio. (2016) Preparation of multiparticulate systems for oral delivery of a micronized or nanosized poorly soluble drug. Drug Development and Industrial Pharmacy 42:9, pages 1466-1475.
Read now
Sin Yee Puah, Hsiu Ni Yap & Cheng Shu Chaw. (2014) Production and characterization of pellets using Avicel CL611 as spheronization aid. Drug Development and Industrial Pharmacy 40:3, pages 418-424.
Read now
N. Vijayakumar, E. Subramanian & D. Pathinettam Padiyan. (2013) Cross-Linked Poly(Vinyl Pyrrolidone) Hard-Template and Polymerization Method in Controlling Nanostructures and Properties of Polyaniline Composites. Polymer-Plastics Technology and Engineering 52:12, pages 1220-1227.
Read now
Hadi Afrasiabi Garekani, Ali Nokhodchi, Mohammad Amirpour Rayeni & Fatemeh Sadeghi. (2013) Preparation and characterization and release properties of Eudragit RS based ibuprofen pellets prepared by extrusion spheronization: effect of binder type and concentration. Drug Development and Industrial Pharmacy 39:8, pages 1238-1246.
Read now
Srimanta Sarkar, Paul W. S. Heng & Celine V. Liew. (2013) Insights into the functionality of pelletization aid in pelletization by extrusion-spheronization. Pharmaceutical Development and Technology 18:1, pages 61-72.
Read now
Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2011) A comparison of chitosan-silica and sodium starch glycolate as disintegrants for spheronized extruded microcrystalline cellulose pellets. Drug Development and Industrial Pharmacy 37:7, pages 825-831.
Read now

Articles from other publishers (21)

Daniel Robin Thio, Paul Wan Sia Heng & Lai Wah Chan. (2022) MUPS Tableting—Comparison between Crospovidone and Microcrystalline Cellulose Core Pellets. Pharmaceutics 14:12, pages 2812.
Crossref
Alberto Berardi, Pauline H.M. Janssen & Bastiaan H.J. DickhoffPhDPhD. (2022) Technical insight into potential functional-related characteristics (FRCs) of sodium starch glycolate, croscarmellose sodium and crospovidone. Journal of Drug Delivery Science and Technology 70, pages 103261.
Crossref
Surendra Agrawal, Joneth Fernandes, Fuzail Shaikh & Vishwa Patel. (2022) Quality aspects in the development of pelletized dosage forms. Heliyon 8:2, pages e08956.
Crossref
Fan Yongbo, Qiao Jiyan, Li Shihai & Feng Chun. (2021) Micron-sized ore powder production by propulsion and rapid unloading of high-pressure gas. Journal of the Australian Ceramic Society 57:5, pages 1489-1497.
Crossref
Ramy N. Elsergany, Lai Wah Chan & Paul Wan Sia Heng. (2020) Cushioning pellets based on microcrystalline cellulose – Crospovidone blends for MUPS tableting. International Journal of Pharmaceutics 586, pages 119573.
Crossref
Ramy N. Elsergany, Vincent Lenhart & Peter Kleinebudde. (2020) Influence of the surface tension of wet massing liquid on the functionality of microcrystalline cellulose as pelletization aid. European Journal of Pharmaceutics and Biopharmaceutics 153, pages 285-296.
Crossref
Hiroomi Sakurai, Yuri Ikeuchi-Takahashi, Ayaka Kobayashi, Nobuyoshi Yoshimura, Chizuko Ishihara, Tohru Aomori & Hiraku Onishi. (2020) Formulation Development of Mucoadhesive Microparticle-Laden Gels for Oral Mucositis: An In Vitro and In Vivo Study. Pharmaceutics 12:7, pages 603.
Crossref
Adrian Szewczyk & Magdalena Prokopowicz. (2020) Mesoporous silica pellets – A promising oral drug delivery system?. Journal of Drug Delivery Science and Technology 56, pages 101491.
Crossref
Katrina M. Hatch, Jana Hlavatá, Katherine Paulett, Tatsiana Liavitskaya, Sergey Vyazovkin & Andrei V. Stanishevsky. (2019) Nanocrystalline Cellulose/Polyvinylpyrrolidone Fibrous Composites Prepared by Electrospinning and Thermal Crosslinking. International Journal of Polymer Science 2019, pages 1-12.
Crossref
Jens Wesholowski, Helmut Podhaisky & Markus Thommes. (2019) Comparison of residence time models for pharmaceutical twin-screw-extrusion processes. Powder Technology 341, pages 85-93.
Crossref
Jana M. Kobeissi, Ghandi F. Hassan & Pierre Karam. (2018) Silver-Modified Cross-Linked Polyvinylpyrrolidone and Its Antibacterial Activity. ACS Applied Bio Materials 1:6, pages 1864-1870.
Crossref
Oisin N. Kavanagh, Ahmad B. Albadarin, Denise M. Croker, Anne Marie Healy & Gavin M. Walker. (2018) Maximising success in multidrug formulation development: A review. Journal of Controlled Release 283, pages 1-19.
Crossref
G. Verstraete, W. De Jaeghere, J. Vercruysse, W. Grymonpr?V. Vanhoorne, F. Stauffer, T. De Beer, A. Bezuijen, J.P. Remon & C. Vervaet. (2017) The use of partially hydrolysed polyvinyl alcohol for the production of high drug-loaded sustained release pellets via extrusion-spheronisation and coating: In vitro and in vivo evaluation. International Journal of Pharmaceutics 517:1-2, pages 88-95.
Crossref
Markus Thommes & Peter Kleinebudde. 2017. Multiparticulate Drug Delivery. Multiparticulate Drug Delivery 37 63 .
Oluwabukola Mustafa & Cheng Shu Chaw. (2016) Silicified microcrystalline cellulose based pellets and their physicochemical properties. Journal of Applied Polymer Science 133:33.
Crossref
Kalyan K. Saripella, Nikhil C. Loka, Rama Mallipeddi, Anuja M. Rane & Steven H. Neau. (2015) A Quality by Experimental Design Approach to Assess the Effect of Formulation and Process Variables on the Extrusion and Spheronization of Drug-Loaded Pellets Containing Polyplasdone® XL-10. AAPS PharmSciTech 17:2, pages 368-379.
Crossref
Srimanta Sarkar, Bee Hwee Ang & Celine Valeria Liew. (2013) Influence of Starting Material Particle Size on Pellet Surface Roughness. AAPS PharmSciTech 15:1, pages 131-139.
Crossref
Srimanta Sarkar, Tin Wui Wong & Celine Valeria Liew. (2013) Importance of Wet Packability of Component Particles in Pellet Formation. AAPS PharmSciTech 14:3, pages 1267-1277.
Crossref
Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2011) Co-processed MCC-Eudragit® E excipients for extrusion–spheronization. European Journal of Pharmaceutics and Biopharmaceutics 79:3, pages 658-663.
Crossref
Peter Kleinebudde. (2011) Pharmazeutisches Produktdesign: Gezielte Freisetzung von Wirkstoffen durch unterschiedliche Extrusionstechniken. Chemie Ingenieur Technik 83:5, pages 589-597.
Crossref
F.J. Otero-Espinar, A. Luzardo-Alvarez & J. Blanco-Méndez. (2010) Non-MCC materials as extrusion-spheronization aids in pellets production. Journal of Drug Delivery Science and Technology 20:4, pages 303-318.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.