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Original Article

Preparation, characterization, and in vivo evaluation of insulin-loaded PLA–PEG microspheres for controlled parenteral drug delivery

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Pages 1364-1374 | Received 28 Dec 2008, Accepted 01 Apr 2009, Published online: 16 Oct 2009

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Read on this site (7)

Chen Li, Long Wan, Jie Luo, Mingyan Jiang & Keke Wang. (2021) Advances in Subcutaneous Delivery Systems of Biomacromolecular Agents for Diabetes Treatment. International Journal of Nanomedicine 16, pages 1261-1280.
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Articles from other publishers (16)

Tovi Shapira‐Furman & Abraham J. Domb. (2023) Insulin Extended Release from PLA‐PEG Stereocomplex Nanoparticles. Macromolecular Bioscience.
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Kumar Kulldeep Niloy & Tao L. Lowe. (2023) Injectable systems for long-lasting insulin therapy. Advanced Drug Delivery Reviews 203, pages 115121.
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Mohammed Ajebli, Haroun Khan & Mohamed Eddouks. (2021) Natural Alkaloids and Diabetes Mellitus: A Review. Endocrine, Metabolic & Immune Disorders - Drug Targets 21:1, pages 111-130.
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Miljana Bacevic, Eric Rompen, Regis Radermecker, Pierre Drion & France Lambert. (2020) Practical considerations for reducing mortality rates in alloxan-induced diabetic rabbits. Heliyon 6:6, pages e04103.
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Lukas Gritsch, Gioacchino Conoscenti, Vincenzo La Carrubba, Patcharakamon Nooeaid & Aldo R. Boccaccini. (2019) Polylactide-based materials science strategies to improve tissue-material interface without the use of growth factors or other biological molecules. Materials Science and Engineering: C 94, pages 1083-1101.
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D. A. Tur, O. B. Shevelev, M. В. Sharapova, M. A. Zolotykh & A. E. Akulov. (2018) The effect of a single administration of streptozotocin on hippocampus metabolites in NODSCID mice. Vavilov Journal of Genetics and Breeding 22:5, pages 600-605.
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B. Mutaliyeva, D. Grigoriev, G. Madybekova, A. Sharipova, S. Aidarova, A. Saparbekova & R. Miller. (2017) Microencapsulation of insulin and its release using w/o/w double emulsion method. Colloids and Surfaces A: Physicochemical and Engineering Aspects 521, pages 147-152.
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Jiannan Li, Jianxun Ding, Tongjun Liu, Jessica F. Liu, Lesan Yan & Xuesi Chen. 2018. Industrial Applications of Poly(lactic acid). Industrial Applications of Poly(lactic acid) 109 138 .
Alexandre Monnier, Charlotte Rombouts, Dania Kouider, Imad About, Hatem Fessi & Nida Sheibat-Othman. (2016) Preparation and characterization of biodegradable polyhydroxybutyrate-co-hydroxyvalerate/polyethylene glycol-based microspheres. International Journal of Pharmaceutics 513:1-2, pages 49-61.
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Yusuf Haggag, Yasser Abdel-Wahab, Opeolu Ojo, Mohamed Osman, Sanaa El-Gizawy, Mohamed El-Tanani, Ahmed Faheem & Paul McCarron. (2016) Preparation and in vivo evaluation of insulin-loaded biodegradable nanoparticles prepared from diblock copolymers of PLGA and PEG. International Journal of Pharmaceutics 499:1-2, pages 236-246.
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Jessica Stukel, Susan Thompson, Laurent Simon & Rebecca Willits. (2015) Polyethlyene glycol microgels to deliver bioactive nerve growth factor. Journal of Biomedical Materials Research Part A 103:2, pages 604-613.
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Tapan Kumar Giri, Chhatrapal Choudhary, Ajazuddin, Amit Alexander, Hemant Badwaik & Dulal Krishna Tripathi. (2013) Prospects of pharmaceuticals and biopharmaceuticals loaded microparticles prepared by double emulsion technique for controlled delivery. Saudi Pharmaceutical Journal 21:2, pages 125-141.
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Aileen JF King. (2012) The use of animal models in diabetes research. British Journal of Pharmacology 166:3, pages 877-894.
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Lin Bi, Lei Yang, Ganesan Narsimhan, Arun K. Bhunia & Yuan Yao. (2011) Designing carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide. Journal of Controlled Release 150:2, pages 150-156.
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