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Original Article

A pH-sensitive nanocomposite microsphere based on chitosan and montmorillonite with in vitro reduction of the burst release effect

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Pages 1106-1114 | Received 06 Dec 2009, Accepted 03 Feb 2010, Published online: 05 Nov 2010

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Read on this site (2)

J. Hecq, F. Siepmann, J. Siepmann, K. Amighi & J. Goole. (2015) Development and evaluation of chitosan and chitosan derivative nanoparticles containing insulin for oral administration. Drug Development and Industrial Pharmacy 41:12, pages 2037-2044.
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Chinmayee Saikia, Anowar Hussain, Anand Ramteke, Hemanta K. Sharma & Tarun K. Maji. (2015) Carboxymethyl starch-chitosan-coated iron oxide magnetic nanoparticles for controlled delivery of isoniazid. Journal of Microencapsulation 32:1, pages 29-39.
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Articles from other publishers (18)

Muhammad Wasim, Fei Shi, Jingxiao Liu, Keya Zhu, Junyan Liu & Tian Yan. (2023) Synthesis of a novel multifunctional montmorillonite/L-malic-acid/curcumin/bacterial cellulose hybrid nanofilm with excellent heat insulation, antibacterial activity and cytocompatibility. Colloid and Polymer Science 301:8, pages 893-908.
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S. RANGA RATHNAM, O. SREEKANTH REDDY & S. B. PATWARI. (2023) DEVELOPMENT AND CHARACTERIZATION OF PH-RESPONSIVE POLYMERIC MICROBEADS INTERCALATED WITH MONTMORILLONITE FOR CONTROLLED RELEASE OF DOXORUBICIN. International Journal of Applied Pharmaceutics, pages 247-253.
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Alireza Ghannad Sabzevari & Hossein Sabahi. (2022) Investigating the Cytotoxicity of Montmorillonite Nanoparticles as a Carrier for Oral Drug Delivery Systems. Investigating the Cytotoxicity of Montmorillonite Nanoparticles as a Carrier for Oral Drug Delivery Systems.
Alireza Ghannad Sabzevari, Hossein Sabahi, Mohsen Nikbakht & Steven J.P. McInnes. (2022) Development and characteristics of layered EGCG/Montmorillonite hybrid: An oral controlled-release formulation of EGCG. Journal of Drug Delivery Science and Technology 76, pages 103750.
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Shabnam Haseli, Mehrab Pourmadadi, Amirmasoud Samadi, Fatemeh Yazdian, Majid Abdouss, Hamid Rashedi & Mona Navaei‐Nigjeh. (2022) A novel pH ‐responsive nanoniosomal emulsion for sustained release of curcumin from a chitosan‐based nanocarrier: Emphasis on the concurrent improvement of loading, sustained release, and apoptosis induction . Biotechnology Progress 38:5.
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Yaqi Yang, Na Yang, Chaolun Zheng & Ziqiang Shao. (2021) Preparation of chitosan nanospheres and optimization of process parameters by response surface method. Polymer Engineering & Science 62:1, pages 201-209.
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O. Sreekanth Reddy, M.C.S. Subha, T. Jithendra, C. Madhavi & K. Chowdoji Rao. (2021) Curcumin encapsulated dual cross linked sodium alginate/montmorillonite polymeric composite beads for controlled drug delivery. Journal of Pharmaceutical Analysis 11:2, pages 191-199.
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Sreekanth Reddy Obireddy, Subha Marata Chinna Subbarao, Krishna Rao Kummari Subba Venkata & Wing‐Fu Lai. (2021) Development and Characterization of Montmorillonite‐Based Hybrid Materials for pH‐Responsive Drug Delivery. ChemistrySelect 6:7, pages 1466-1470.
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Su Young Jung, Ju-Hwan Park, Min-Jun Baek, Gyu-Ho Kim, Jaehwan Kim, Hong-Mei Zheng, Jae-Min Kim, Il-Mo Kang, Dae-Duk Kim & Jangik I. Lee. (2020) Development of an oral bentonite-based modified-release freeze-dried powder of vactosertib: Pharmacokinetics and anti-colitis activity in rodent models of ulcerative colitis. International Journal of Pharmaceutics 578, pages 119103.
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Soontaree (Grace) Intasa-ard & Makoto Ogawa. 2018. Mesoporous Silica-based Nanomaterials and Biomedical Applications, Part B. Mesoporous Silica-based Nanomaterials and Biomedical Applications, Part B 117 136 .
Patrícia H. Yassue-Cordeiro, Patrícia Severino, Eliana B. Souto, Eliezer L. Gomes, Cristiana M.P. Yoshida, Mariana A. de Moraes & Classius F. da Silva. 2018. Applications of Nanocomposite Materials in Drug Delivery. Applications of Nanocomposite Materials in Drug Delivery 1 26 .
Ju-Hwan Park, Hyeon-Jong Shin, Min Hwan Kim, Ji-Su Kim, Naewon Kang, Jae-Young Lee, Ki-Taek Kim, Jangik Ike Lee & Dae-Duk Kim. (2016) Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems. Journal of Pharmaceutical Investigation 46:4, pages 363-375.
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Mandip Sarmah, Nibedita Banik, Anowar Hussain, Anand Ramteke, Hemanta K. Sharma & Tarun K. Maji. (2015) Study on crosslinked gelatin–montmorillonite nanoparticles for controlled drug delivery applications. Journal of Materials Science 50:22, pages 7303-7313.
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Chinmayee Saikia, Anowar Hussain, Anand Ramteke, Hemanta K. Sharma, Pritam Deb & Tarun K. Maji. (2015) Carboxymethyl starch-coated iron oxide magnetic nanoparticles: a potential drug delivery system for isoniazid. Iranian Polymer Journal 24:10, pages 815-828.
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B.P. da Costa Neto, A.L.M.L. da Mata, Milene V. Lopes, B. Rossi-Bergmann & M.I. Ré. (2014) Preparation and evaluation of chitosan–hydrophobic silica composite microspheres: Role of hydrophobic silica in modifying their properties. Powder Technology 255, pages 109-119.
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Nibedita Banik, Murshid Iman, Anowar Hussain, Anand Ramteke, Ratan Boruah & Tarun K. Maji. (2013) Soy flour nanoparticles for controlled drug delivery: effect of crosslinker and montmorillonite (MMT). New Journal of Chemistry 37:12, pages 3981.
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Vivek K Garripelli & Seongbong Jo. (2012) Nanocomposite thermogel for controlled release of small proteins. Journal of Bioactive and Compatible Polymers 27:3, pages 198-209.
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Anca Cojocariu, Lenuta Profire, Magdalena Aflori & Cornelia Vasile. (2012) In vitro drug release from chitosan/Cloisite 15A hydrogels. Applied Clay Science 57, pages 1-9.
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