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Original Article

Formulation development and in vitro evaluation of didanosine-loaded nanostructured lipid carriers for the potential treatment of AIDS dementia complex

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Pages 396-407 | Received 29 Apr 2010, Accepted 11 Aug 2010, Published online: 06 Oct 2010

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Ruchika M. Bondre, Pranita S. Kanojiya, Rita N. Wadetwar & Priya S. Kangali. (2023) Sustained vaginal delivery of in situ gel containing Voriconazole nanostructured lipid carrier: formulation, in vitro and ex vivo evaluation. Journal of Dispersion Science and Technology 44:8, pages 1466-1478.
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Georgia I. Sakellari, Ioanna Zafeiri, Hannah Batchelor & Fotis Spyropoulos. (2021) Formulation design, production and characterisation of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the encapsulation of a model hydrophobic active. Food Hydrocolloids for Health 1, pages 100024.
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Saif Ahmad Khan, Saleha Rehman, Bushra Nabi, Ashif Iqubal, Nida Nehal, Usama A. Fahmy, Sabna Kotta, Sanjula Baboota, Shadab Md & Javed Ali. (2020) Boosting the Brain Delivery of Atazanavir through Nanostructured Lipid Carrier-Based Approach for Mitigating NeuroAIDS. Pharmaceutics 12:11, pages 1059.
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Walid Anwar, Hamdy Dawaba, Mohsen Afouna, Ahmed Samy, Mohammed Rashed & Abdelaziz Abdelaziz. (2020) Enhancing the Oral Bioavailability of Candesartan Cilexetil Loaded Nanostructured Lipid Carriers: In Vitro Characterization and Absorption in Rats after Oral Administration. Pharmaceutics 12:11, pages 1047.
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Gulin Amasya, Buket Aksu, Ulya Badilli, Arzu Onay-Besikci & Nilufer Tarimci. (2019) QbD guided early pharmaceutical development study: Production of lipid nanoparticles by high pressure homogenization for skin cancer treatment. International Journal of Pharmaceutics 563, pages 110-121.
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Bushra Nabi, Saleha Rehman, Sanjula Baboota & Javed Ali. (2019) Insights on Oral Drug Delivery of Lipid Nanocarriers: a Win-Win Solution for Augmenting Bioavailability of Antiretroviral Drugs. AAPS PharmSciTech 20:2.
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Olga Krasodomska, Patrizia Paolicelli, Stefania Cesa, Maria Antonietta Casadei & Christian Jungnickel. (2016) Protection and viability of fruit seeds oils by nanostructured lipid carrier (NLC) nanosuspensions. Journal of Colloid and Interface Science 479, pages 25-33.
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Rendra Tofani, Yeyet Sumirtapura & Sasanti Darijanto. (2016) Formulation, Characterisation, and in Vitro Skin Diffusion of Nanostructured Lipid Carriers for Deoxyarbutin Compared to a Nanoemulsion and Conventional Cream. Scientia Pharmaceutica 84:4, pages 634-645.
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Gulin Amasya, Ulya Badilli, Buket Aksu & Nilufer Tarimci. (2016) Quality by design case study 1: Design of 5-fluorouracil loaded lipid nanoparticles by the W/O/W double emulsion — Solvent evaporation method. European Journal of Pharmaceutical Sciences 84, pages 92-102.
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Ranjita Shegokar. 2015. Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases. Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases 233 249 .
Kuruva Chandra Sekhar, S. K. Thaslim Basha, Cherukupalle Bhuvaneswar, Baki Vijaya Bhaskar, Wudayagiri Rajendra, Chamarthi Naga Raju & S. K. Ghosh. (2014) Didanosine phosphoramidates: synthesis, docking to viral NA, antibacterial and antiviral activity. Medicinal Chemistry Research 24:1, pages 209-219.
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Petra O. Nnamani, Steffi Hansen, Maike Windbergs & Claus-Michael Lehr. (2014) Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application. International Journal of Pharmaceutics 477:1-2, pages 208-217.
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Katia P. Seremeta, María I. Reyes Tur, Sandra Martínez Pérez, Christian Höcht, Carlos Taira, Orestes D. López Hernández & Alejandro Sosnik. (2014) Spray-dried didanosine-loaded polymeric particles for enhanced oral bioavailability. Colloids and Surfaces B: Biointerfaces 123, pages 515-523.
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Kuruva Chandra Sekhar, Avilala Janardhan, Yellapu Nanda Kumar, Golla Narasimha, Chamarthi Naga Raju & S. K. Ghosh. (2014) Amino Acid Esters Substituted Phosphorylated Emtricitabine and Didanosine Derivatives as Antiviral and Anticancer Agents. Applied Biochemistry and Biotechnology 173:6, pages 1303-1318.
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Elsabé Jones, Elizabeth Ojewole, Viness Pillay, Pradeep Kumar, Sanjeev Rambharose & Thirumala Govender. (2013) Monolayered multipolymeric buccal films with drug and polymers of opposing solubilities for ARV therapy: Physico-mechanical evaluation and molecular mechanics modelling. International Journal of Pharmaceutics 455:1-2, pages 197-212.
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Shegokar Ranjita. (2013) Nanosuspensions: a new approach for organ and cellular targeting in infectious diseases. Journal of Pharmaceutical Investigation 43:1, pages 1-26.
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Patrícia Severino, Heloisa Silva, Eliana B. Souto, Maria Helena A. Santana & Teresa Cristina T. Dalla Costa. (2012) Analysis of in vivo absorption of didanosine tablets in male adult dogs by HPLC. Journal of Pharmaceutical Analysis 2:1, pages 29-34.
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W.A. Kasongo, Jana Pardeike, Rainer H. Müller & Roderick B. Walker. (2011) Selection and Characterization of Suitable Lipid Excipients for use in the Manufacture of Didanosine-Loaded Solid Lipid Nanoparticles and Nanostructured Lipid Carriers. Journal of Pharmaceutical Sciences 100:12, pages 5185-5196.
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