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Research Article

A comparison of chitosan-silica and sodium starch glycolate as disintegrants for spheronized extruded microcrystalline cellulose pellets

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Pages 825-831 | Received 10 Jun 2010, Accepted 01 Dec 2010, Published online: 15 Mar 2011

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Hadi Afrasiabi Garekani, Seyede Fatemeh Aftabi, Fatemeh Fahimi Nia, Mohammad Javidi, Ali Nokhodchi & Fatemeh Sadeghi. (2019) Synergistic effect of polyethylene glycol and superdisintegrant on dissolution rate enhancement of simvastatin in pellet formulation. Pharmaceutical Development and Technology 24:6, pages 720-728.
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Yu Xia, Chun-Yang Shi, Jian-Guo Fang & Wen-Qing Wang. (2018) Approaches to developing fast release pellets via wet extrusion-spheronization. Pharmaceutical Development and Technology 23:5, pages 432-441.
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Ihatanderson Alves-Silva, Ricardo N. Marreto, Guilherme M. Gelfuso, Lívia C. L. Sá-Barreto, Eliana M. Lima & Marcílio S. S. Cunha-Filho. (2017) Preparation of benznidazole pellets for immediate drug delivery using the extrusion spheronization technique. Drug Development and Industrial Pharmacy 43:5, pages 762-769.
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Matteo Cerea, Franco Pattarino, Andrea Foglio Bonda, Luca Palugan, Lorena Segale & Carlo Vecchio. (2016) Preparation of multiparticulate systems for oral delivery of a micronized or nanosized poorly soluble drug. Drug Development and Industrial Pharmacy 42:9, pages 1466-1475.
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Mozhgan Sadeghi, Salar Hemmati & Hamed Hamishehkar. (2016) Synthesis of a novel superdisintegrant by starch derivatization with polysuccinimide and its application for the development of Ondansetron fast dissolving tablet. Drug Development and Industrial Pharmacy 42:5, pages 769-775.
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Alvaro Goyanes & Ramón Martínez-Pacheco. (2015) New co-processed MCC-based excipient for fast release of low solubility drugs from pellets prepared by extrusion-spheronization. Drug Development and Industrial Pharmacy 41:3, pages 362-368.
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Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2013) Chitosan–kaolin coprecipitate as disintegrant in microcrystalline cellulose-based pellets elaborated by extrusion–spheronization. Pharmaceutical Development and Technology 18:1, pages 137-145.
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Articles from other publishers (6)

Hardika Rana, Mansi Dholakia, Mukesh Gohel, Abdelwahab Omri, Vaishali Thakkar & Tejal Gandhi. (2021) Demonstration of Advanced Data Mining Tools for Optimization of Pellets Employing Modified Extrusion-pelletization Technique. Current Drug Therapy 16:2, pages 154-169.
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Hardik Rana, Vaishali Thakkar, Kalpana Mudgal, Mukesh Gohel, Lalji Baldania, Mansi Dholakia & Tejal Gandhi. (2019) Systematic Scrutinisation of Vital Factors for Fabrication and Evaluation of PGS-MCC Based Drug Loaded Pellets by Extrusion Spheronization Technique. Current Drug Therapy 14:2, pages 168-182.
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Hetal Patel, Hiral Patel, Mukesh Gohel & Sanjay Tiwari. (2016) Dissolution rate improvement of telmisartan through modified MCC pellets using 32 full factorial design. Saudi Pharmaceutical Journal 24:5, pages 579-587.
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Thanh Huong Hoang Thi, Siham Lhafidi, Simone Pinto Carneiro & Marie-Pierre Flament. (2015) Feasability of a new process to produce fast disintegrating pellets as novel multiparticulate dosage form for pediatric use. International Journal of Pharmaceutics 496:2, pages 842-849.
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Marlies Kubbinga, Peter Langguth & Dirk Barends. (2013) Risk analysis in bioequivalence and biowaiver decisions. Biopharmaceutics & Drug Disposition 34:5, pages 254-261.
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Alvaro Goyanes, Consuelo Souto & Ramón Martínez-Pacheco. (2011) Co-processed MCC-Eudragit® E excipients for extrusion–spheronization. European Journal of Pharmaceutics and Biopharmaceutics 79:3, pages 658-663.
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