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Research Article

Suitability of various excipients as carrier and coating materials for liquisolid compacts

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Pages 1200-1207 | Received 02 Nov 2010, Accepted 15 Feb 2011, Published online: 31 Mar 2011

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Sung-Up Choi & Seong-Wan Cho. (2013) Formulation of Liquid Choline Alphoscerate as a Solid Dosage Form. Journal of the Korea Academia-Industrial cooperation Society 14:12, pages 6324-6329.
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Angel Tan, Shasha Rao & Clive A. Prestidge. (2013) Transforming Lipid-Based Oral Drug Delivery Systems into Solid Dosage Forms: An Overview of Solid Carriers, Physicochemical Properties, and Biopharmaceutical Performance. Pharmaceutical Research 30:12, pages 2993-3017.
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Suhas G. Gumaste, Damon M. Dalrymple & Abu T. M. Serajuddin. (2013) Development of Solid SEDDS, V: Compaction and Drug Release Properties of Tablets Prepared by Adsorbing Lipid-Based Formulations onto Neusilin® US2. Pharmaceutical Research 30:12, pages 3186-3199.
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Claudia Kutza, Hendrik Metz, Johannes Kutza, Frank Syrowatka & Karsten Mäder. (2013) Toward a detailed characterization of oil adsorbates as “solid liquids”. European Journal of Pharmaceutics and Biopharmaceutics 84:1, pages 172-182.
Crossref
C.M. Hentzschel, M. Alnaief, I. Smirnova, A. Sakmann & C.S. Leopold. (2012) Enhancement of griseofulvin release from liquisolid compacts. European Journal of Pharmaceutics and Biopharmaceutics 80:1, pages 130-135.
Crossref

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