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Research Article

Buccoadhesive films for once-a-day administration of rivastigmine: systematic formulation development and pharmacokinetic evaluation

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Pages 466-480 | Received 22 Nov 2011, Accepted 06 Feb 2012, Published online: 12 Mar 2012

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Javier Avendaño-Godoy, Arnoldo Miranda, Sigrid Mennickent & Carolina Gómez-Gaete. (2023) Intramuscularly Administered PLGA Microparticles for Sustained Release of Rivastigmine: In Vitro, In Vivo and Histological Evaluation. Journal of Pharmaceutical Sciences 112:12, pages 3175-3184.
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Salwa & Lalit Kumar. (2023) Quality-by-design driven analytical method (AQbD) development and validation of HPLC–UV technique to quantify rivastigmine hydrogen tartrate in lipidic nanocarriers: Forced degradation, and assessment of drug content and in vitro release studies. Microchemical Journal 193, pages 108944.
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Dalia A. Farghaly, Samar A. Afifi, Ahmed A. Aboelwafa & Magdy I. Mohamed. (2023) Oral Dissolving Film of Rivastigmine: Optimization Using Factorial Design. Journal of Pharmaceutical Innovation.
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Mohamed Haider, Ibrahim Elsayed, Iman S. Ahmed & Ahmed R. Fares. (2021) In Situ-Forming Microparticles for Controlled Release of Rivastigmine: In Vitro Optimization and In Vivo Evaluation. Pharmaceuticals 14:1, pages 66.
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Yi-gong Guo & Anubhav Pratap Singh. (2019) Emerging strategies for enhancing buccal and sublingual administration of nutraceuticals and pharamaceuticals. Journal of Drug Delivery Science and Technology 52, pages 440-451.
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Bruno Fonseca-Santos & Marlus Chorilli. (2018) An overview of polymeric dosage forms in buccal drug delivery: State of art, design of formulations and their in vivo performance evaluation. Materials Science and Engineering: C 86, pages 129-143.
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Mario Jug, Anita Hafner, Jasmina Lovrić, Maja Lusina Kregar, Ivan Pepić, Željka Vanić, Biserka Cetina-Čižmek & Jelena Filipović-Grčić. (2018) An overview of in vitro dissolution/release methods for novel mucosal drug delivery systems. Journal of Pharmaceutical and Biomedical Analysis 147, pages 350-366.
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Emil Meng-Lund, Jette Jacobsen, Anette Müllertz, Erling B. Jørgensen & René Holm. (2016) Buccal absorption of diazepam is improved when administered in bioadhesive tablets—An in vivo study in conscious Göttingen mini-pigs. International Journal of Pharmaceutics 515:1-2, pages 125-131.
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Sanjay Bansal, Sarwar Beg, Babita Garg, Abhay Asthana, Gyati S. Asthana & Bhupinder Singh. (2015) QbD-Oriented Development and Characterization of Effervescent Floating-Bioadhesive Tablets of Cefuroxime Axetil. AAPS PharmSciTech 17:5, pages 1086-1099.
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Alice Simon, Maria Inês Amaro, Lucio Mendes Cabral, Anne Marie Healy & Valeria Pereira de Sousa. (2016) Development of a novel dry powder inhalation formulation for the delivery of rivastigmine hydrogen tartrate. International Journal of Pharmaceutics 501:1-2, pages 124-138.
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Maria Inês Amaro, Alice Simon, Lúcio Mendes Cabral, Valéria Pereira de Sousa & Anne Marie Healy. (2015) Rivastigmine hydrogen tartrate polymorphs: Solid-state characterisation of transition and polymorphic conversion via milling. Solid State Sciences 49, pages 29-36.
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Emil Meng-Lund, Eva Marxen, Anne Marie L. Pedersen, Anette Müllertz, Birgitte Hyrup, Rene Holm & Jette Jacobsen. (2014) Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa. Journal of Pharmaceutical Sciences 103:7, pages 2053-2061.
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Emil Meng-Lund, Jette Jacobsen, Liang Jin, Christian Janfelt, René Holm, Anette Müllertz & Joseph A. Nicolazzo. (2014) Azone® Decreases the Buccal Mucosal Permeation of Diazepam in a Concentration-Dependent Manner via a Reservoir Effect. Journal of Pharmaceutical Sciences 103:4, pages 1133-1141.
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Viralkumar F. Patel, Fang Liu & Marc B. Brown. (2012) Modeling the oral cavity: In vitro and in vivo evaluations of buccal drug delivery systems. Journal of Controlled Release 161:3, pages 746-756.
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