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Drug Development and Industrial Pharmacy Volume 38, 2012 - Issue 5
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Research Article

Improved initial burst of estradiol organogel as long-term in situ drug delivery implant: formulation, in vitro and in vivo characterization

Yang YangSchool of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR China
,
Lu XuSchool of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR China
,
Yanan GaoSchool of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR China
,
Qifang WangSchool of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR China
,
Xin CheSchool of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR China
&
Sanming LiSchool of Pharmaceutics, Shenyang Pharmaceutical University, Shenyang, Liaoning, PR ChinaCorrespondence[email protected]
Pages 550-556 | Received 12 Jan 2012, Accepted 06 Feb 2012, Published online: 15 Mar 2012

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Song Yang, Mengya Hu, Wenqing Liu, Nuohan Hou, Kaidi Yin, Chen Shen & Qing Shang. (2021) Fabrication of PLGA in situ forming implants and study on their correlation of in vitro release profiles with in vivo performances. Journal of Biomaterials Science, Polymer Edition 32:8, pages 994-1008.
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Beibei Hu, Haipeng Yan, Yanping Sun, Xi Chen, Yujuan Sun, Sanming Li, Yongshuai Jing & Heran Li. (2020) Organogels based on amino acid derivatives and their optimization for drug release using response surface methodology. Artificial Cells, Nanomedicine, and Biotechnology 48:1, pages 266-275.
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Zhen Li, Jinxu Cao, Beibei Hu, Heran Li, Hongzhuo Liu, Fei Han, Zhenyun Liu, Chao Tong & Sanming Li. (2016) Studies on the in vitro and in vivo degradation behavior of amino acid derivative-based organogels. Drug Development and Industrial Pharmacy 42:11, pages 1732-1741.
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Zhen Li, Jinxu Cao, Heran Li, Hongzhuo Liu, Fei Han, Zhenyun Liu, Chao Tong & Sanming Li. (2016) Self-assembled drug delivery system based on low-molecular-weight bis-amide organogelator: synthesis, properties and in vivo evaluation. Drug Delivery 23:8, pages 3168-3178.
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Xiaowei Zhang, Chong Zhang, Wei Zhang, Shu Meng, Danhua Liu, Ping Wang, Jing Guo, Jianxin Li, Yanmin Guan & Dan Yang. (2015) Feasibility of poly (ε-caprolactone-co-DL-lactide) as a biodegradable material for in situ forming implants: evaluation of drug release and in vivo degradation. Drug Development and Industrial Pharmacy 41:2, pages 342-352.
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Wang Lihong, Che Xin, Guo Yongxue, Bian Yiying & Cheng Gang. (2014) Thermoresponsive ophthalmic poloxamer/tween/carbopol in situ gels of a poorly water-soluble drug fluconazole: preparation and in vitro–in vivo evaluation. Drug Development and Industrial Pharmacy 40:10, pages 1402-1410.
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Mahfoozur Rahman, Waleed H. Almalki, Saad Alghamdi, Khalid S. Alharbi, Habibullah Khalilullah, Md. Habban Akhter, Amit K. Keshari, Nisha Sharma, Tanuja Singh, Kriti Soni, Abdul Hafeez & Sarwar Beg. (2021) Three ‘D’s: Design approach, dimensional printing, and drug delivery systems as promising tools in healthcare applications. Drug Discovery Today 26:11, pages 2726-2733.
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Muge Kilicarslan & Ayse Nur Buke. (2021) An Overview: The Evaluation of Formation Mechanisms, Preparation Techniques and Chemical and Analytical Characterization Methods of the In Situ Forming Implants. Current Pharmaceutical Analysis 17:3, pages 375-408.
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Sarwar Beg, Mahfoozur Rahman, S.M. Kawish, Abdul Qadir, Mohamad Taleuzzaman, Rafida Ilyas, Kainat Alam & Rahul Shukla. 2021. Nanoformulation Strategies for Cancer Treatment. Nanoformulation Strategies for Cancer Treatment 353 364 .
Manman Dai, Luyu Bai, Huimin Zhang, Qun Ma, Rui Luo, Fang Lei, Qingsong Fei & Ning He. (2020) A novel flunarizine hydrochloride-loaded organogel for intraocular drug delivery in situ: Design, physicochemical characteristics and inspection. International Journal of Pharmaceutics 576, pages 119027.
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Sarwar Beg, Mahfoozur Rahman & Kanchan Kohli. (2019) Quality-by-design approach as a systematic tool for the development of nanopharmaceutical products. Drug Discovery Today 24:3, pages 717-725.
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Geeta Aggarwal & Manju Nagpal. 2018. Polymer Gels. Polymer Gels 249 284 .
Bhupinder Singh, Sumant Saini, Shikha Lohan & Sarwar Beg. 2017. Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes. Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes 110 148 .
Dipak K. Shah, Sai S. Sagiri, B. Behera, Kunal Pal & Krishna Pramanik. (2013) Development of olive oil based organogels using sorbitan monopalmitate and sorbitan monostearate: A comparative study. Journal of Applied Polymer Science 129:2, pages 793-805.
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Cecile A. Lagadec & David. K. Smith. (2012) Structure?activity effects in peptide self-assembly and gelation ? Dendritic versus linear architectures. Chemical Communications 48:63, pages 7817.
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