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Drug Development and Industrial Pharmacy Volume 39, 2013 - Issue 10
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Research Article

Investigation for the amorphous state of ER-34122, a dual 5-lipoxygenase/cyclooxygenase inhibitor with poor aqueous solubility, in HPMC solid dispersion prepared by the solvent evaporation method

Ikuo KushidaAnalytical Research, CMC Japan, Pharmaceutical Science & Technology Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Tokodai, Tsukuba, Ibaraki, JapanCorrespondence[email protected]
&
Masaharu GotodaAnalytical Research, CMC Japan, Pharmaceutical Science & Technology Core Function Unit, Eisai Product Creation Systems, Eisai Co., Ltd., Tokodai, Tsukuba, Ibaraki, Japan
Pages 1582-1588 | Received 01 Feb 2012, Accepted 16 Mar 2012, Published online: 20 Apr 2012

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Read on this site (2)

Sumit Kumar Saha, Amita Joshi, Romi Singh & Kiran Dubey. (2023) Review of industrially recognized polymers and manufacturing processes for amorphous solid dispersion based formulations. Pharmaceutical Development and Technology 28:7, pages 678-696.
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Fan Meng, Urvi Gala & Harsh Chauhan. (2015) Classification of solid dispersions: correlation to (i) stability and solubility (ii) preparation and characterization techniques. Drug Development and Industrial Pharmacy 41:9, pages 1401-1415.
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Articles from other publishers (6)

Uttom Nandi, Adejumoke Lara Ajiboye, Preksha Patel, Dennis Douroumis & Vivek Trivedi. (2021) Preparation of Solid Dispersions of Simvastatin and Soluplus Using a Single-Step Organic Solvent-Free Supercritical Fluid Process for the Drug Solubility and Dissolution Rate Enhancement. Pharmaceuticals 14:9, pages 846.
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Mridul Majumder, Saeid Rajabnezhad, Ali Nokhodchi & Mohammed Maniruzzaman. (2018) Chemico-calorimetric analysis of amorphous granules manufactured via continuous granulation process. Drug Delivery and Translational Research 8:6, pages 1658-1669.
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Khadijah Edueng, Denny Mahlin & Christel A. S. Bergström. (2017) The Need for Restructuring the Disordered Science of Amorphous Drug Formulations. Pharmaceutical Research 34:9, pages 1754-1772.
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Zheng Lu, Yonglai Yang, Rae-Ann Covington, Yunxia (Vivian) Bi, Thomas Dürig, Marc A. Ilies & Reza Fassihi. (2016) Supersaturated controlled release matrix using amorphous dispersions of glipizide. International Journal of Pharmaceutics 511:2, pages 957-968.
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M. Maniruzzaman, A. Nair, N. Scoutaris, Michael S.A. Bradley, M.J. Snowden & D. Douroumis. (2015) One-step continuous extrusion process for the manufacturing of solid dispersions. International Journal of Pharmaceutics 496:1, pages 42-51.
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Mohammed Maniruzzaman, Muhammad T. Islam, Hiren G. Moradiya, Sheelagh A. Halsey, Ian J. Slipper, Baburz Chowdhry, Martin J. Snowden & Dennis Douroumis. (2014) Prediction of Polymorphic Transformations of Paracetamol in Solid Dispersions. Journal of Pharmaceutical Sciences 103:6, pages 1819-1828.
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