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Research Article

Novel taste-masked orally disintegrating tablets for a highly soluble drug with an extremely bitter taste: design rationale and evaluation

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Pages 1364-1371 | Received 27 Dec 2011, Accepted 01 Aug 2012, Published online: 20 Sep 2012

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Read on this site (3)

Raphael Wiedey, Marcel Kokott & Jörg Breitkreutz. (2021) Orodispersible tablets for pediatric drug delivery: current challenges and recent advances. Expert Opinion on Drug Delivery 18:12, pages 1873-1890.
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Kai Bin Liew, Yvonne Tze Fung Tan & Kok Khiang Peh. (2015) Taste-masked and affordable donepezil hydrochloride orally disintegrating tablet as promising solution for non-compliance in Alzheimer’s disease patients. Drug Development and Industrial Pharmacy 41:4, pages 583-593.
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Areeg Anwer Ali, Naseem Ahmad Charoo & Daud Baraka Abdallah. (2014) Pediatric drug development: formulation considerations. Drug Development and Industrial Pharmacy 40:10, pages 1283-1299.
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Articles from other publishers (15)

Okhee Yoo, Sam Salman, Britta S. von Ungern-Sternberg & Lee Yong Lim. (2023) Taste-Masked Flucloxacillin Powder Part 1: Optimisation of Fabrication Process Using a Mixture Design Approach. Pharmaceuticals 16:8, pages 1171.
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Khater AL-Japairai, Samah Hamed Almurisi, Abd Almonem Doolaanea, Syed Mahmood, Fawaz Alheibshy, Ahmed Alobaida, Nadiya Abdul-Halim & Bappaditya Chatterjee. (2023) A review on taste masked multiparticulate dosage forms for paediatric. International Journal of Pharmaceutics 632, pages 122571.
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Ji Yu, Jin Xie, Huijuan Xie, Qi Hu, Zhenfeng Wu, Xinfu Cai, Zhiping Guo, Junzhi Lin, Li Han & Dingkun Zhang. (2022) Strategies for Taste Masking of Orodispersible Dosage Forms: Time, Concentration, and Perception. Molecular Pharmaceutics 19:9, pages 3007-3025.
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Kai Bin Liew, Long Chiau Ming, Bey-Hing Goh & Kok Khiang Peh. (2022) Fast Melt Cocoa Butter Tablet: Effect of Waxes, Starch, and PEG 6000 on Physical Properties of the Preparation. Molecules 27:10, pages 3128.
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Kai Bin Liew & Kok Khiang Peh. (2015) Investigation on the effect of polymer and starch on the tablet properties of lyophilized orally disintegrating tablet. Archives of Pharmacal Research 44:8, pages 1-10.
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Sandip Pawar & Pravin Shende. (2021) Design and optimization of cyclodextrin-based nanosponges of antimalarials using central composite design for dry suspension. Journal of Inclusion Phenomena and Macrocyclic Chemistry 99:3-4, pages 169-183.
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Shrestha Prabhat, Shrestha Rajan & Shrestha Sahana. (2021) Formulation and evaluation of orally disintegrating tablet containing taste masked mirtazapine. Journal of Analytical & Pharmaceutical Research 10:2, pages 71-80.
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Miguel Moreira & Mafalda Sarraguça. (2020) How can oral paediatric formulations be improved? A challenge for the XXI century. International Journal of Pharmaceutics 590, pages 119905.
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May Almukainzi, Gabriel L. B. Araujo & Raimar Löbenberg. (2018) Orally disintegrating dosage forms. Journal of Pharmaceutical Investigation 49:2, pages 229-243.
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Alison V. Keating, Jessica Soto, Catherine Tuleu, Claire Forbes, Min Zhao & Duncan Q.M. Craig. (2018) Solid state characterisation and taste masking efficiency evaluation of polymer based extrudates of isoniazid for paediatric administration. International Journal of Pharmaceutics 536:2, pages 536-546.
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S Mansi, Menra Muse, J. S. Dua, M. Singh & D. N. Prasad. (2017) TASTE MASKING TECHNIQUES: A REVIEW. INDIAN DRUGS 54:02, pages 5-19.
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Sara M. Hanning, Felipe L. Lopez, Ian C.K. Wong, Terry B. Ernest, Catherine Tuleu & Mine Orlu Gul. (2016) Patient centric formulations for paediatrics and geriatrics: Similarities and differences. International Journal of Pharmaceutics 512:2, pages 355-359.
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Abeer H.A. Mohamed-Ahmed, Jessica Soto, Terry Ernest & Catherine Tuleu. (2016) Non-human tools for the evaluation of bitter taste in the design and development of medicines: a systematic review. Drug Discovery Today 21:7, pages 1170-1180.
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Wasfy M. Obeidat, Ali Nokhodchi & Hatim Alkhatib. (2015) Evaluation of Matrix Tablets Based on Eudragit®E100/Carbopol®971P Combinations for Controlled Release and Improved Compaction Properties of Water Soluble Model Drug Paracetamol. AAPS PharmSciTech 16:5, pages 1169-1179.
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Kenjirou Higashi, Kazutoshi Yamamoto, Manoj Kumar Pandey, Kamal H. Mroue, Kunikazu Moribe, Keiji Yamamoto & Ayyalusamy Ramamoorthy. (2013) Insights into Atomic-Level Interaction between Mefenamic Acid and Eudragit EPO in a Supersaturated Solution by High-Resolution Magic-Angle Spinning NMR Spectroscopy. Molecular Pharmaceutics 11:1, pages 351-357.
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