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Drug Development and Industrial Pharmacy Volume 39, 2013 - Issue 9
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Research Article

Pharmacokinetics and tissue distribution of amphotericin B following oral administration of three lipid-based formulations to rats

Fady IbrahimFaculty of pharmaceutical sciences, the University of British Columbia, Vancouver, BC, CanadaCorrespondence[email protected]
,
Pavel GershkovichFaculty of pharmaceutical sciences, the University of British Columbia, Vancouver, BC, Canada
,
Olena SivakFaculty of pharmaceutical sciences, the University of British Columbia, Vancouver, BC, Canada
,
Ellen K. Wasan
&
Kishor M. WasanFaculty of pharmaceutical sciences, the University of British Columbia, Vancouver, BC, Canada
Pages 1277-1283 | Received 25 Jun 2012, Accepted 06 Aug 2012, Published online: 18 Sep 2012

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Read on this site (4)

Tian Fu, Jinglin Yi, Songyi Lv & Bing Zhang. (2017) Ocular amphotericin B delivery by chitosan-modified nanostructured lipid carriers for fungal keratitis-targeted therapy. Journal of Liposome Research 27:3, pages 228-233.
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Guo Shan-Bin, Tian Yue & Jian Ling-Yan. (2015) Long-term sustained-released in situ gels of a water-insoluble drug amphotericin B for mycotic arthritis intra-articular administration: preparation, in vitro and in vivo evaluation. Drug Development and Industrial Pharmacy 41:4, pages 573-582.
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Tao Li, Ya-Jun Shu, Jia-Yin Cheng, Run-Cheng Liang, Shao-Na Dian, Xiao-Xun Lv, Meng-Qi Yang, Shu-Ling Huang, Gang Chen & Fan Yang. (2015) Pharmacokinetics and efficiency of brain targeting of ginsenosides Rg1 and Rb1 given as Nao-Qing microemulsion. Drug Development and Industrial Pharmacy 41:2, pages 224-231.
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Shyam Sundar & Jaya Chakravarty. (2015) Investigational drugs for visceral leishmaniasis. Expert Opinion on Investigational Drugs 24:1, pages 43-59.
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Articles from other publishers (11)

Erfan Abdollahizad, Simin Dadashzadeh, Shima Bahri, Zahra Abbasian & Elham Rezaee. (2023) Amphotericin B Pharmacokinetics: Inter-strain Differences in Rats Following Intravenous Administration of the Most Commonly Marketed Formulations of the Drug. Iranian Journal of Pharmaceutical Research 22:1.
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Roohi Kesharwani, Pankaj Jaiswal, Dilip Kumar Patel & Pankaj Kumar Yadav. (2022) Lipid-Based Drug Delivery System (LBDDS): An Emerging Paradigm to Enhance Oral Bioavailability of Poorly Soluble Drugs. Biomedical Materials & Devices.
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Garrett Davis, Anjali Kurse, Anupam Agarwal, David Sheikh-Hamad & M.N.V.Ravi Kumar. (2022) Nano-encapsulation strategies to circumvent drug-induced kidney injury and targeted nanomedicines to treat kidney diseases. Current Opinion in Toxicology 31, pages 100346.
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Priyanka Mazire, Vartika Agarwal & Amit Roy. (2021) Road‐map of pre‐clinical treatment for Visceral Leishmaniasis. Drug Development Research 83:2, pages 317-327.
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Sandra Elisa Haas, Tamara Ramos Maciel & Marcelo Gomes de Gomes. 2021. Applications of Nanobiotechnology for Neglected Tropical Diseases. Applications of Nanobiotechnology for Neglected Tropical Diseases 243 252 .
Kishor M. Wasan. (2020) Development of an Oral Amphotericin B Formulation as an Alternative Approach to Parenteral Amphotericin B Administration in the Treatment of Blood-Borne Fungal Infections. Current Pharmaceutical Design 26:14, pages 1521-1523.
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Wioleta Cieslik, Joanna Szczepaniak, Anna Krasowska & Robert Musiol. (2020) Antifungal Styryloquinolines as Candida albicans Efflux Pump Inhibitors: Styryloquinolines are ABC Transporter Inhibitors. Molecules 25:2, pages 345.
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A. Wu, E. Grela, K. Wójtowicz, N. Filipczak, Y. Hamon, R. Luchowski, W. Grudziński, O. Raducka-Jaszul, M. Gagoś, A. Szczepaniak, G. Chimini, W. I. Gruszecki & T. Trombik. (2019) ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells. Cellular and Molecular Life Sciences 76:24, pages 4979-4994.
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Aline de Souza, Débora Soares Souza Marins, Samir Leite Mathias, Lis Marie Monteiro, Megumi Nishitani Yukuyama, Cauê Benito Scarim, Raimar Löbenberg & Nádia Araci Bou-Chacra. (2018) Promising nanotherapy in treating leishmaniasis. International Journal of Pharmaceutics 547:1-2, pages 421-431.
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Shyam Sundar & Anup Singh. (2016) Recent developments and future prospects in the treatment of visceral leishmaniasis. Therapeutic Advances in Infectious Disease 3:3-4, pages 98-109.
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Paloma Benito-Gallo, Alessandro Franceschetto, Jonathan C.M. Wong, Maria Marlow, Vanessa Zann, Peter Scholes & Pavel Gershkovich. (2015) Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis. European Journal of Pharmaceutics and Biopharmaceutics 93, pages 353-362.
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