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Drug Development and Industrial Pharmacy Volume 40, 2014 - Issue 6
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Research Article

Sildenafil vaginal suppositories: preparation, characterization, in vitro and in vivo evaluation

Srinivasan ShanmugamPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth Korea
,
Young-Hun KimPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth Korea
,
Jeong-Hee ParkPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth Korea
,
Ho Taek ImPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth Korea
,
Young Taek SohnCollege of Pharmacy, Duksung Women’s University Dobong-Gu, SeoulSouth Korea
,
Kyeong Soo KimPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth Korea
,
Yong-Il KimPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth Korea
,
Chul Soon YongCollege of Pharmacy, Yeungnam University GyongsanSouth Korea
,
Jong Oh KimCollege of Pharmacy, Yeungnam University GyongsanSouth Korea
,
Han-Gon ChoiCollege of Pharmacy, Hanyang University AnsanRepublic of KoreaCorrespondence[email protected]
&
Jong Soo WooPharm. R&D Institute, Hanmi Pharm. Co., Ltd. Hwasung, GyeonggiSouth KoreaCorrespondence[email protected]
 show all
Pages 803-812 | Received 06 Dec 2012, Accepted 16 Mar 2013, Published online: 19 Jun 2013

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Heba M. Aboud, Amira H. Hassan, Adel A. Ali & Abdel-Razik H. Abdel-Razik. (2018) Novel in situ gelling vaginal sponges of sildenafil citrate-based cubosomes for uterine targeting. Drug Delivery 25:1, pages 1328-1339.
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Ghareb M. Soliman, Gihan Fetih & Ahmed M. Abbas. (2017) Thermosensitive bioadhesive gels for the vaginal delivery of sildenafil citrate: in vitro characterization and clinical evaluation in women using clomiphene citrate for induction of ovulation. Drug Development and Industrial Pharmacy 43:3, pages 399-408.
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Articles from other publishers (11)

Mohammadreza Abbaspour, Hoda Hoseini, Zahra Sobhani, Seyed Ahmad Emami, Bibi Sedigheh Fazly Bazzaz & Behjat Javadi. (2022) Development and Evaluation of Vaginal Suppository Containing Althaea officinalis L. Polysaccharide Extract. Brazilian Journal of Pharmaceutical Sciences 58.
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Awais Mushtaq, Abdul Baseer, Syed Saoud Zaidi, Muhammad Waseem Khan, Sajiha Batool, Ehsan Elahi, Waqar Aman, Muhammad Naeem & Fakhar ud Din. (2022) Fluconazole-loaded thermosensitive system: In vitro release, pharmacokinetics and safety study. Journal of Drug Delivery Science and Technology 67, pages 102972.
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Mohammed Ghazwani, Umme Hani, Riyaz Ali M. Osmani, Mohamed Rahamathulla, M. Yasmin Begum, Shadma Wahab, D. V. Gowda, Akhila Akkihebbal Ravikumar, Honnavalli Yogish kumar, Hissana Ather & Afrasim Moin. (2021) An Efficient Herbal Approach for Treating Fungal Infection in Cervical Cancer Patients by Developing and Optimizing a Vaginal Suppository. International Journal of Polymer Science 2021, pages 1-11.
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Monika Kniotek, Michał Zych, Aleksander Roszczyk, Monika Szafarowska & Małgorzata Maria Jerzak. (2021) Decreased Production of TNF-α and IL-6 Inflammatory Cytokines in Non-Pregnant Idiopathic RPL Women Immunomodulatory Effect of Sildenafil Citrate on the Cellular Response of Idiopathic RPL Women. Journal of Clinical Medicine 10:14, pages 3115.
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Jung Suk Kim, Fakhar ud Din, Sang Min Lee, Dong Shik Kim, Yoo Jin Choi, Mi Ran Woo, Jong Oh Kim, Yu Seok Youn, Sung Giu Jin & Han-Gon Choi. (2021) Comparative study between high-pressure homogenisation and Shirasu porous glass membrane technique in sildenafil base-loaded solid SNEDDS: Effects on physicochemical properties and in vivo characteristics. International Journal of Pharmaceutics 592, pages 120039.
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A. Correia, C.P. Costa, V. Silva, R. Silva, J.M. Sousa Lobo & A.C. Silva. (2020) Pessaries containing nanostructured lipid carriers (NLC) for prolonged vaginal delivery of progesterone. European Journal of Pharmaceutical Sciences 153, pages 105475.
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Deepa Negi, Amandeep Singh, Navin Joshi & Neeraj Mishra. (2020) Cisplatin and Probiotic Biomass Loaded Pessaries for the Management of Cervical Cancer. Anti-Cancer Agents in Medicinal Chemistry 20:5, pages 589-598.
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Ci Ren, Xiaomin Li, Lu Mao, Jinfeng Xiong, Chun Gao, Hui Shen, Liming Wang, Da Zhu, Wencheng Ding & Hui Wang. (2019) An effective and biocompatible polyethylenimine based vaginal suppository for gene delivery. Nanomedicine: Nanotechnology, Biology and Medicine 20, pages 101994.
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Eman Gomaa, Amr S. Abu Lila, Azza A. Hasan & Fakhr-eldin S. Ghazy. (2018) Preparation and characterization of intravaginal vardenafil suppositories targeting a complementary treatment to boost in vitro fertilization process. European Journal of Pharmaceutical Sciences 111, pages 113-120.
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Fohona S. Coulibaly, Miezan J. M. Ezoulin, Sudhaunshu S. Purohit, Navid J. Ayon, Nathan A. Oyler & Bi-Botti C. Youan. (2017) Layer-by-Layer Engineered Microbicide Drug Delivery System Targeting HIV-1 gp120: Physicochemical and Biological Properties. Molecular Pharmaceutics 14:10, pages 3512-3527.
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Sanjida Mahjabeen, Manolya K. Hatipoglu, Vishal Chandra, Doris M. Benbrook & Lucila Garcia-Contreras. (2017) Optimization of a Vaginal Suppository Formulation to Deliver SHetA2 as a Novel Treatment for Cervical Dysplasia. Journal of Pharmaceutical Sciences.
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