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Drug Development and Industrial Pharmacy Volume 40, 2014 - Issue 8
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Research Article

Effect of polymers and media type on extending the dissolution of amorphous pioglitazone and inhibiting the recrystallization from a supersaturated state

Nian-Qiu ShiThe State Key Laboratories of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research TianjinP.R. China
,
Jing YaoThe State Key Laboratories of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research TianjinP.R. China;College of Pharmacy, Henan University, Kaifeng Henan ProvinceP.R. China
&
Xing-Lin WangThe State Key Laboratories of Drug Delivery Technology and Pharmacokinetics, Tianjin Institute of Pharmaceutical Research TianjinP.R. ChinaCorrespondence[email protected]
Pages 1112-1122 | Received 28 Feb 2013, Accepted 21 May 2013, Published online: 28 Jun 2013

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Nian-Qiu Shi, Hong-Wei Lai, Yong Zhang, Bo Feng, Xiao Xiao, Hong-Mei Zhang, Zheng-Qiang Li & Xian-Rong Qi. (2018) On the inherent properties of Soluplus and its application in ibuprofen solid dispersions generated by microwave-quench cooling technology. Pharmaceutical Development and Technology 23:6, pages 573-586.
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Yang Guo, Ting Zhong, Xiao-Chuan Duan, Shuang Zhang, Xin Yao, Yi-Fan Yin, Dan Huang, Wei Ren, Qiang Zhang & Xuan Zhang. (2017) Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix. Drug Delivery 24:1, pages 270-277.
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Anna Penkina, Kristian Semjonov, Maija Hakola, Sirpa Vuorinen, Timo Repo, Jouko Yliruusi, Jaan Aruväli, Karin Kogermann, Peep Veski & Jyrki Heinämäki. (2016) Towards improved solubility of poorly water-soluble drugs: cryogenic co-grinding of piroxicam with carrier polymers. Drug Development and Industrial Pharmacy 42:3, pages 378-388.
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Articles from other publishers (7)

Huan Yu, Yanfei Zhang, Yinghui Ma, Huifeng Zhang, Chengyi Hao, Yong Zhang, Zhengqiang Li, Xianrong Qi & Nianqiu Shi. (2022) Hot Melt Extrusion-Triggered Amorphization as a Continuous Process for Inducing Extended Supersaturable Drug Immediate-Release from saSMSDs Systems. Pharmaceutics 14:4, pages 765.
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Ya-Wei Li, Hong-Mei Zhang, Bai-Ji Cui, Cheng-Yi Hao, He-Yun Zhu, Jiao Guan, Dan Wang, Ying Jin, Bo Feng, Jian-Hui Cai, Xian-Rong Qi & Nian-Qiu Shi. (2021) “Felodipine-indomethacin” co-amorphous supersaturating drug delivery systems: “Spring-parachute” process, stability, in vivo bioavailability, and underlying molecular mechanisms. European Journal of Pharmaceutics and Biopharmaceutics 166, pages 111-125.
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Khan Viet Nguyen, Ivo Laidmäe, Karin Kogermann, Andres Lust, Andres Meos, Duc Viet Ho, Ain Raal, Jyrki Heinämäki & Hoai Thi Nguyen. (2019) Preformulation Study of Electrospun Haemanthamine-Loaded Amphiphilic Nanofibers Intended for a Solid Template for Self-Assembled Liposomes. Pharmaceutics 11:10, pages 499.
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Sang Yeob Park, Zion Kang, Prakash Thapa, Yong Suk Jin, Joo Won Park, Hye Jung Lim, Jae Young Lee, Sa-Won Lee, Min-Hyo Seo, Min-Soo Kim & Seong Hoon Jeong. (2019) Development of sorafenib loaded nanoparticles to improve oral bioavailability using a quality by design approach. International Journal of Pharmaceutics 566, pages 229-238.
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Nian-Qiu Shi, Shu-Ran Wang, Yong Zhang, Jun-Shuang Huo, Li-Na Wang, Jian-Hui Cai, Zheng-Qiang Li, Bai Xiang & Xian-Rong Qi. (2019) Hot melt extrusion technology for improved dissolution, solubility and “spring-parachute” processes of amorphous self-micellizing solid dispersions containing BCS II drugs indomethacin and fenofibrate: Profiles and mechanisms. European Journal of Pharmaceutical Sciences 130, pages 78-90.
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Nian-Qiu Shi, Yong Zhang, Yan Li, Hong-Wei Lai, Xiao Xiao, Bo Feng & Xian-Rong Qi. (2017) Self-micellizing solid dispersions enhance the properties and therapeutic potential of fenofibrate: Advantages, profiles and mechanisms. International Journal of Pharmaceutics 528:1-2, pages 563-577.
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Niraj S. Trasi & Lynne S. Taylor. (2015) Dissolution performance of binary amorphous drug combinations—Impact of a second drug on the maximum achievable supersaturation. International Journal of Pharmaceutics 496:2, pages 282-290.
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