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Drug Development and Industrial Pharmacy Volume 40, 2014 - Issue 10
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Research Article

A simple pharmacokinetic model of alendronate developed using plasma concentration and urine excretion data from healthy men

Jung-woo ChaeCollege of Pharmacy, Chungnam National University DaejeonKorea
,
Jeong-won SeoNew Drug Research Team, NiFDS Chungcheongbuk-doKorea
,
Bimit MahatCollege of Pharmacy, Chungnam National University DaejeonKorea
,
Hwi-yeol YunUppsala Pharmacometrics, Uppsala University UppsalaSweden
,
In-hwan BaekCollege of Pharmacy, Chungnam National University DaejeonKorea
,
Byung-yo LeeCollege of Pharmacy, Chungnam National University DaejeonKorea
,
Dong-hyun KimHanmi Research Center Hwaseong-siKorea
&
Kwang-il KwonCollege of Pharmacy, Chungnam National University DaejeonKoreaCorrespondence[email protected]
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Pages 1325-1329 | Received 02 Oct 2012, Accepted 17 Jun 2013, Published online: 25 Jul 2013

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Yu Wang, Jing Yang, Yanfang Guo, Haipeng Wang, Yalan Liu, Huiming Huang & Baogang Xie. (2016) A novel HPLC-UV method for determining alendronate in rat plasma through precolumn derivatization with phenyl isothiocyanate: Application to pharmacokinetics. Journal of Liquid Chromatography & Related Technologies 39:17-18, pages 815-820.
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Articles from other publishers (9)

Anna Di Vito, Emanuela Chiarella, Jessica Sovereto, Jessica Bria, Ida Daniela Perrotta, Alessandro Salatino, Francesco Baudi, Alessandro Sacco, Alessandro Antonelli, Flavia Biamonte, Tullio Barni & Amerigo Giudice. (2023) Novel insights into the pharmacological modulation of human periodontal ligament stem cells by the amino-bisphosphonate Alendronate. European Journal of Cell Biology 102:4, pages 151354.
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Wladimir Gushiken de Campos, Rita Araújo, Celso Augusto Lemos Júnior & Pedro de Sousa Gomes. (2023) Alendronate induces skeletal alterations in the chicken embryonic development model. Toxicology and Applied Pharmacology, pages 116673.
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Hideaki Ishii, Mariko Shibuya, Gary Ngai‐Wa Leung, Shozo Yamashita, Shun‐ichi Nagata, Asuka Kushiro, Satoshi Sakai, Kota Toju, Jun Okada, Kazumi Kawasaki, Kanichi Kusano & Isao Kijima‐Suda. (2022) Additional studies on nicotine exposure in horses: Accurate quantification and elimination profiles of potential biomarkers in plasma and urine. Rapid Communications in Mass Spectrometry 36:23.
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Somying Patntirapong. (2022) Duration and timing of bisphosphonate treatment as factors determining osteoblast mineralization. Journal of Oral Biology and Craniofacial Research 12:5, pages 575-579.
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José L. Calvo-Gallego, Peter Pivonka, Rocío Ruiz-Lozano & Javier Martínez-Reina. (2022) Mechanistic PK-PD model of alendronate treatment of postmenopausal osteoporosis predicts bone site-specific response. Frontiers in Bioengineering and Biotechnology 10.
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Somying Patntirapong, Pawinee Phupunporn, Daranee Vanichtantiphong & Watcharawee Thanetchaloempong. (2019) Inhibition of macrophage viability by bound and free bisphosphonates. Acta Histochemica 121:4, pages 400-406.
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Somying Patntirapong & Mahatana Poolgesorn. (2018) Alteration of macrophage viability, differentiation, and function by bisphosphonates. Oral Diseases 24:7, pages 1294-1302.
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Miho Yamada, Xiao-Pen Lee, Masaya Fujishiro, Ken Iseri, Makoto Watanabe, Hiroshi Sakamaki, Naoki Uchida, Takaaki Matsuyama, Takeshi Kumazawa, Haruo Takahashi, Akira Ishii & Keizo Sato. (2018) Highly sensitive determination of alendronate in human plasma and dialysate using metal-free HPLC-MS/MS. Legal Medicine 30, pages 14-20.
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Isaac Zentner, Hans P. Schlecht, Lorna Khensouvann, Neo Tamuhla, Michele Kutzler, Vijay Ivaturi, Jotam G. Pasipanodya, Tawanda Gumbo, Charles A. Peloquin, Gregory P. Bisson & Christopher Vinnard. (2016) Urine colorimetry to detect Low rifampin exposure during tuberculosis therapy: a proof-of-concept study. BMC Infectious Diseases 16:1.
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