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Research Article

Influence of alkalizers on dissolution properties of telmisartan in solid dispersions prepared by cogrinding

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Pages 1660-1669 | Received 14 May 2013, Accepted 28 Aug 2013, Published online: 07 Oct 2013

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Read on this site (3)

Mehmet Birer & Füsun Acartürk. (2021) Electrospun orally disintegrating film formulation of telmisartan. Pharmaceutical Development and Technology 26:6, pages 661-672.
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Alaa Y. Bazeed, Ebtessam A. Essa, Ahmed Nouh & Gamal M. El Maghraby. (2020) Co-processing of nateglinide with meglumine for enhanced dissolution rate: in vitro and in vivo evaluation. Drug Development and Industrial Pharmacy 46:10, pages 1676-1683.
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Anna Penkina, Kristian Semjonov, Maija Hakola, Sirpa Vuorinen, Timo Repo, Jouko Yliruusi, Jaan Aruväli, Karin Kogermann, Peep Veski & Jyrki Heinämäki. (2016) Towards improved solubility of poorly water-soluble drugs: cryogenic co-grinding of piroxicam with carrier polymers. Drug Development and Industrial Pharmacy 42:3, pages 378-388.
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Articles from other publishers (13)

Manami Dhibar, Santanu Chakraborty, Souvik Basak, Paramita Pattanayak, Tanmay Chatterjee, Balaram Ghosh, Mohamed Raafat & Mohammed A. S. Abourehab. (2023) Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment. Pharmaceuticals 16:2, pages 284.
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Ahmed Almotairy, Mashan Almutairi, Abdulmajeed Althobaiti, Mohammed Alyahya, Sandeep Sarabu, Abdullah Alzahrani, Feng Zhang, Suresh Bandari & Michael A. Repka. (2021) Effect of pH modifiers on the solubility, dissolution rate, and stability of telmisartan solid dispersions produced by hot-melt extrusion technology. Journal of Drug Delivery Science and Technology 65, pages 102674.
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Nitin Kumar Bhatt, Jamshed Haneef, Manish Vyas & Gopal L. Khatik. (2021) Development of L-Lysine Amino Acid-Based Co-Crystal of Telmisartan Using Crystal Engineering Approach to Improve Solubility, Dissolution, and Micrometric Properties. Current Drug Delivery 18:5, pages 596-606.
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Xiangjun Shi, Xiyue Zhou, Shuimei Shen, Qifeng Chen, Shengjie Song, Chenru Gu & Chao Wang. (2021) Improved in vitro and in vivo properties of telmisartan in the co-amorphous system with hydrochlorothiazide: A potential drug-drug interaction mechanism prediction. European Journal of Pharmaceutical Sciences 161, pages 105773.
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Khater A. S. Al-Japairai, Hala M. Alkhalidi, Syed Mahmood, Samah H. Almurisi, Abd Almonem Doolaanea, Taha A. Al-Sindi & Bappaditya Chatterjee. (2020) Lyophilized Amorphous Dispersion of Telmisartan in a Combined Carrier–Alkalizer System: Formulation Development and In Vivo Study . ACS Omega 5:50, pages 32466-32480.
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Zhi Wang, Bei-Ni Ye, Yong-Tai Zhang, Jian-Xu Xie, Wan-Si Li, Hong-Tao Zhang, Ying Liu & Nian-Ping Feng. (2019) Exploring the Potential of Mesoporous Silica as a Carrier for Puerarin: Characterization, Physical Stability, and In Vivo Pharmacokinetics. AAPS PharmSciTech 20:7.
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Mani Ganesh, Udhumansha Ubaidulla, Grace Rathnam & Hyun Tae Jang. (2019) Chitosan-telmisartan polymeric cocrystals for improving oral absorption: In vitro and in vivo evaluation. International Journal of Biological Macromolecules 131, pages 879-885.
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Xiangjun Shi, Tiantian Xu, Wan Huang, Baibai Fan & Xiaoxia Sheng. (2019) Stability and Bioavailability Enhancement of Telmisartan Ternary Solid Dispersions: the Synergistic Effect of Polymers and Drug-Polymer(s) Interactions. AAPS PharmSciTech 20:4.
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Jun Soo Chae, Bo Ram Chae, Dong Jun Shin, Yoon Tae Goo, Eun Seok Lee, Ho Yub Yoon, Chang Hyun Kim & Young Wook Choi. (2018) Tablet Formulation of a Polymeric Solid Dispersion Containing Amorphous Alkalinized Telmisartan. AAPS PharmSciTech 19:7, pages 2990-2999.
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Monica R. P. Rao, Jagruti Chaudhari, Francesco Trotta & Fabrizio Caldera. (2018) Investigation of Cyclodextrin-Based Nanosponges for Solubility and Bioavailability Enhancement of Rilpivirine. AAPS PharmSciTech 19:5, pages 2358-2369.
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Wenhao Xu, Ying Sun, Liping Du, Yulia S. Chistyachenko, Alexandr V. Dushkin & Weike Su. (2018) Investigations on solid dispersions of valsartan with alkalizing agents: Preparation, characterization and physicochemical properties. Journal of Drug Delivery Science and Technology 44, pages 399-405.
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Enikő Borbás, Zsombor K. Nagy, Brigitta Nagy, Attila Balogh, Balázs Farkas, Oksana Tsinman, Konstantin Tsinman & Bálint Sinkó. (2018) The effect of formulation additives on in vitro dissolution-absorption profile and in vivo bioavailability of telmisartan from brand and generic formulations. European Journal of Pharmaceutical Sciences 114, pages 310-317.
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Jaywant N. Pawar, Harita R. Desai, Kailas K. Moravkar, Deepak K. Khanna & Purnima D. Amin. (2016) Exploring the potential of porous silicas as a carrier system for dissolution rate enhancement of artemether. Asian Journal of Pharmaceutical Sciences 11:6, pages 760-770.
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